Lexeo Therapeutics, Inc. (LXEO) Institutional Ownership

Institutions by Trading Activity

38,876,296Shares Outstanding

226Shares held by institutions

$2,382Value of institutional holdings

0.05%Institutional ownership %

8,269.91%Shares Changed QoQ

3No. of institutional investors

The institutional landscape for Lexeo Therapeutics, Inc. (NASDAQ:LXEO) includes 3 filers as of the latest reporting cycle ending December 2025.

The percentage of Lexeo Therapeutics owned by institutions changed from 126.9% in September 2025 to 0.0% in December 2025, marking a slight down trend.
Quarterly data indicates a 8269.91% shift in institutional share volume, and the annual owner count reflects a decrease of 96.67%.
Of these 3 institutional investors, 2 increased their holdings in Lexeo Therapeutics, while 0 of them reduced positions, and 1 investors maintained their exposure.
The total number of shares held by institutions in Lexeo Therapeutics increased to 18.92K as of December 2025, a net change of up by 18.69K shares quarter on quarter, and down 29.50Mn shares year over year.
The top institutional stake in Lexeo Therapeutics as of December 31, 2025 belongs to SG Americas Securities, LLC, which owns 18.64K shares, or 0.05% of the company.
Among the most significant buyers of Lexeo Therapeutics during December 2025 were SG Americas Securities, LLC (18.64K), GAMMA Investing LLC (50).
The top 3 institutional holders of Lexeo Therapeutics for the quarter ending December 2025 included SG Americas Securities, LLC (18.64K), True Wealth Design, LLC (226), GAMMA Investing LLC (50).

226 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JANUS HENDERSON GROUP PLC	30 Sep, 2025	6,105,527	2,421,144	65.71%	$40,492,761.00
Frazier Life Sciences Management, L.P.	30 Sep, 2025	4,424,725	0	0.00%	$29,380,174.00
BALYASNY ASSET MANAGEMENT L.P.	30 Sep, 2025	3,913,788	-95,349	-2.38%	$25,987,552.00
Affinity Asset Advisors, LLC	30 Sep, 2025	3,870,527	281,172	7.83%	$25,700,299.00
CITADEL ADVISORS LLC	30 Sep, 2025	3,719,043	3,719,043	0.00%	$24,694,446.00
Vestal Point Capital, LP	30 Sep, 2025	3,250,000	21,839	0.68%	$21,580,000.00
Woodline Partners LP	30 Sep, 2025	2,572,162	0	0.00%	$17,079,156.00
MILLENNIUM MANAGEMENT LLC	30 Sep, 2025	2,313,642	-522,650	-18.43%	$15,362,583.00
VANGUARD GROUP INC	30 Sep, 2025	2,226,290	223,424	11.16%	$14,782,566.00
BlackRock, Inc.	30 Sep, 2025	2,171,092	343,128	18.77%	$14,416,051.00
Point72 Asset Management, L.P.	30 Sep, 2025	1,941,849	1,293,969	199.72%	$12,893,875.00
ADAR1 Capital Management, LLC	30 Sep, 2025	1,531,953	1,386,844	955.73%	$10,172,168.00
Blackstone Inc.	30 Sep, 2025	1,124,922	0	0.00%	$7,469,482.00
D1 Capital Partners L.P.	30 Sep, 2025	978,652	0	0.00%	$6,498,249.00
683 Capital Management, LLC	30 Sep, 2025	922,662	922,662	0.00%	$6,126,476.00
DIMENSIONAL FUND ADVISORS LP	30 Sep, 2025	912,533	865,510	1,840.61%	$6,059,280.00
SILVERARC CAPITAL MANAGEMENT, LLC	30 Sep, 2025	778,611	778,611	0.00%	$5,169,977.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	721,881	143,800	24.88%	$4,794,441.00
Siren, L.L.C.	30 Sep, 2025	603,435	0	0.00%	$4,006,808.00
Ikarian Capital, LLC	30 Sep, 2025	567,601	17,572	3.19%	$3,768,870.00

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