Lexeo Therapeutics, Inc. (LXEO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

54,001,214Shares Outstanding

10,373,767Shares held by institutions

$101,351,704Value of institutional holdings

91.35%Institutional ownership %

25.42%Shares Changed QoQ

109No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Lexeo Therapeutics, Inc. (NASDAQ:LXEO) currently has 109 active institutional owners and shareholders as of today (September 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Lexeo Therapeutics saw its institutional ownership percentage fell to 91.4% in September 2025 from 116.5% in June 2025.
Quarterly data indicates a 25.42% shift in institutional share volume, and the annual owner count reflects an increase of 57.97%.
During the quarter, 76 institutions bought more Lexeo Therapeutics shares, 16 sold shares, and 17 of the 109 total investors held their position steady.
The aggregate institutional position in Lexeo Therapeutics now stands at 49.33Mn shares as of September 2025, after investors increased their holdings (up by 10.00Mn shares quarter on quarter which is up 19.57Mn shares year over year).
JANUS HENDERSON GROUP PLC continues to be the largest institutional holder of Lexeo Therapeutics as of September 30, 2025, with a position of 6.11Mn shares, representing 11.31% of the company's outstanding stock.
Among the most significant buyers of Lexeo Therapeutics during September 2025 were JANUS HENDERSON GROUP PLC (2.42Mn), ADAR1 Capital Management, LLC (1.39Mn), Point72 Asset Management, L.P. (1.29Mn), CITADEL ADVISORS LLC (995.68K), 683 Capital Management, LLC (922.66K).
Leading sellers of Lexeo Therapeutics stock in September 2025 included MILLENNIUM MANAGEMENT LLC (522.65K), BALYASNY ASSET MANAGEMENT L.P. (95.35K), UBS Group AG (22.00K), DAFNA Capital Management LLC (20.00K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (19.08K).
The top 10 institutional holders of Lexeo Therapeutics for the quarter ending September 2025 included JANUS HENDERSON GROUP PLC (6.11Mn), Frazier Life Sciences Management, L.P. (4.42Mn), BALYASNY ASSET MANAGEMENT L.P. (3.91Mn), Affinity Asset Advisors, LLC (3.87Mn), CITADEL ADVISORS LLC (3.72Mn), Vestal Point Capital, LP (3.25Mn), Woodline Partners LP (2.57Mn), MILLENNIUM MANAGEMENT LLC (2.31Mn), VANGUARD GROUP INC (2.23Mn), BlackRock, Inc. (2.17Mn).

109 Institutional Holders

10,373,767 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JANUS HENDERSON GROUP PLC	30 Sep, 2025	6,105,527	2,421,144	65.71%	$40,492,761.00
Frazier Life Sciences Management, L.P.	30 Sep, 2025	4,424,725	0	0.00%	$29,380,174.00
BALYASNY ASSET MANAGEMENT L.P.	30 Sep, 2025	3,913,788	-95,349	-2.38%	$25,987,552.00
Affinity Asset Advisors, LLC	30 Sep, 2025	3,870,527	281,172	7.83%	$25,700,299.00
CITADEL ADVISORS LLC	30 Sep, 2025	3,719,043	995,680	36.56%	$24,694,446.00
Vestal Point Capital, LP	30 Sep, 2025	3,250,000	21,839	0.68%	$21,580,000.00
Woodline Partners LP	30 Sep, 2025	2,572,162	0	0.00%	$17,079,156.00
MILLENNIUM MANAGEMENT LLC	30 Sep, 2025	2,313,642	-522,650	-18.43%	$15,362,583.00
VANGUARD GROUP INC	30 Sep, 2025	2,226,290	223,424	11.16%	$14,782,566.00
BlackRock, Inc.	30 Sep, 2025	2,171,092	343,128	18.77%	$14,416,051.00
Point72 Asset Management, L.P.	30 Sep, 2025	1,941,849	1,293,969	199.72%	$12,893,875.00
ADAR1 Capital Management, LLC	30 Sep, 2025	1,531,953	1,386,844	955.73%	$10,172,168.00
Blackstone Inc.	30 Sep, 2025	1,124,922	0	0.00%	$7,469,482.00
D1 Capital Partners L.P.	30 Sep, 2025	978,652	0	0.00%	$6,498,249.00
683 Capital Management, LLC	30 Sep, 2025	922,662	922,662	0.00%	$6,126,476.00
DIMENSIONAL FUND ADVISORS LP	30 Sep, 2025	912,533	865,510	1,840.61%	$6,059,280.00
SILVERARC CAPITAL MANAGEMENT, LLC	30 Sep, 2025	778,611	778,611	0.00%	$5,169,977.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	721,881	143,800	24.88%	$4,794,441.00
Siren, L.L.C.	30 Sep, 2025	603,435	0	0.00%	$4,006,808.00
Ikarian Capital, LLC	30 Sep, 2025	567,601	17,572	3.19%	$3,768,870.00

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Lexeo Therapeutics, Inc. (LXEO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

109 Institutional Holders

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