Lexeo Therapeutics (LXEO) Operating Income (2022 - 2026)

Lexeo Therapeutics (LXEO) posted Operating Income of -$22.3 million for Q1 2026, up 3.39% sequentially from -$23.1 million in Q4 2025, and up 33.94% YoY from -$16.7 million in Q1 2025.

Lexeo Therapeutics (LXEO) Operating Income (2022 - 2026) Analysis & Trends

Lexeo Therapeutics has reported Operating Income for 5 years, with the latest figure at -$22.3 million in Q1 2026.

  • Quarterly Operating Income rose 33.94% year-over-year to -$22.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$97.8 million (up 15.91% YoY) and the FY2025 annual result came in at -$109.3 million, down 3.3% from the prior year.
  • Operating Income climbed to -$22.3 million in Q1 2026 per LXEO's latest filing, from -$23.1 million in the prior quarter.
  • Over five years, Operating Income peaked at -$14.0 million in Q2 2023 and troughed at -$33.8 million in Q1 2025.
  • A 5-year average of -$22.6 million and a median of -$22.3 million in 2026 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2024 and 2026: Operating Income plunged 82.86% in 2024, then surged 33.94% in 2026.
  • Over 5 years, Operating Income stood at -$15.2 million in 2022, then climbed by 1.47% to -$15.0 million in 2023, then slumped by 82.86% to -$27.4 million in 2024, then advanced by 15.58% to -$23.1 million in 2025, then rose by 3.39% to -$22.3 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$22.3 million, -$23.1 million, and -$21.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Lexeo Therapeutics 397.10 Mn 397.10 Mn - -28.02 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -28.02 Mn
Mar 31, 2026 -22.33 Mn
Dec 31, 2025 -23.12 Mn
Sep 30, 2025 -21.65 Mn
Jun 30, 2025 -30.69 Mn
Mar 31, 2025 -33.81 Mn
Dec 31, 2024 -27.38 Mn
Sep 30, 2024 -31.54 Mn
Jun 30, 2024 -23.55 Mn
Mar 31, 2024 -23.29 Mn
Dec 31, 2023 -14.97 Mn
Sep 30, 2023 -20.27 Mn
Jun 30, 2023 -13.98 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.20 Mn
Sep 30, 2022 -17.48 Mn