Growth Metrics

Lexeo Therapeutics (LXEO) Operating Income (2022 - 2026)

Lexeo Therapeutics recorded quarterly Operating Income of -$22.3 million in Q1 2026, up 3.39% quarter-over-quarter from -$23.1 million in Q4 2025, and up 33.94% year-over-year from -$16.7 million in Q1 2025.

Lexeo Therapeutics' Operating Income history runs 5 years deep, the most recent figure standing at -$22.3 million for Q1 2026.

  • In Q1 2026, Operating Income rose 33.94% year-over-year to -$22.3 million; the TTM figure through Mar 2026 stood at -$97.8 million (down 213.56% YoY), while the FY2025 annual figure was -$109.3 million, down 428.55% from the prior year.
  • Operating Income came in at -$22.3 million for Q1 2026 at Lexeo Therapeutics, up from -$23.1 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $57.7 million in Q4 2024 to a low of -$33.8 million in Q1 2025.
  • A 5-year average of -$16.9 million and a median of -$21.6 million in 2025 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income soared 485.42% in 2024 and plunged 140.05% in 2025, its largest moves.
  • Lexeo Therapeutics' Operating Income stood at -$15.2 million in 2022, then advanced by 1.47% to -$15.0 million in 2023, then jumped by 485.42% to $57.7 million in 2024, then slumped by 140.05% to -$23.1 million in 2025, then increased by 3.39% to -$22.3 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$22.3 million, -$23.1 million, and -$21.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Lexeo Therapeutics 392.12 Mn 199.07 Mn - -22.33 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -22.33 Mn
Dec 31, 2025 -23.12 Mn
Sep 30, 2025 -21.65 Mn
Jun 30, 2025 -30.69 Mn
Mar 31, 2025 -33.81 Mn
Dec 31, 2024 57.71 Mn
Sep 30, 2024 -31.54 Mn
Jun 30, 2024 -23.55 Mn
Mar 31, 2024 -23.29 Mn
Dec 31, 2023 -14.97 Mn
Sep 30, 2023 -20.27 Mn
Jun 30, 2023 -13.98 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.20 Mn
Sep 30, 2022 -17.48 Mn