Growth Metrics

LeonaBio (LONA) Change in Cash (2019 - 2026)

LeonaBio (LONA) reported Change in Cash of -$36.4 million for Q1 2026, down 65.53% year-over-year from -$105.7 million in Q1 2025, and down 175.29% on a QoQ basis from $48.4 million in Q4 2025.

LeonaBio (LONA) has 8 years of Change in Cash data on file, last reported at -$36.4 million in Q1 2026.

  • Quarterly Change in Cash fell 65.53% year-over-year to -$36.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $6.4 million (up 112.47% YoY) and the FY2025 annual result came in at $20.8 million, up 149.44% from the prior year.
  • Change in Cash slipped to -$36.4 million in Q1 2026 per LONA's latest filing, from $48.4 million in the prior quarter.
  • Across five years, Change in Cash topped out at $48.4 million in Q4 2025 and bottomed at -$36.4 million in Q1 2026.
  • The 5-year median for Change in Cash is -$5.0 million (2024), against an average of -$4.5 million.
  • The widest annual swing landed in 2022, when Change in Cash sank 686.75%; it then surged 268.12% in 2025.
  • Tracing LONA's Change in Cash over 5 years: stood at $9.1 million in 2022, then plunged by 316.39% to -$19.8 million in 2023, then tumbled by 45.78% to -$28.8 million in 2024, then surged by 268.12% to $48.4 million in 2025, then sank by 175.29% to -$36.4 million in 2026.
  • Per Business Quant, the three latest LONA Change in Cash figures stand at -$36.4 million (Q1 2026), $48.4 million (Q4 2025), and $986000.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 2.44 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 53.61 Mn
10 LeonaBio 181.52 Mn 113.84 Mn - -36.44 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -36.44 Mn
Dec 31, 2025 48.40 Mn
Sep 30, 2025 986,000.00
Jun 30, 2025 -6.53 Mn
Mar 31, 2025 -22.02 Mn
Dec 31, 2024 -28.79 Mn
Sep 30, 2024 -4.97 Mn
Jun 30, 2024 4.38 Mn
Mar 31, 2024 -12.76 Mn
Dec 31, 2023 -19.75 Mn
Sep 30, 2023 -3.29 Mn
Jun 30, 2023 8.45 Mn
Mar 31, 2023 9.43 Mn
Dec 31, 2022 9.13 Mn
Sep 30, 2022 -8.01 Mn
Jun 30, 2022 -22.75 Mn
Mar 31, 2022 7.48 Mn
Dec 31, 2021 3.21 Mn
Sep 30, 2021 -24.37 Mn
Jun 30, 2021 3.88 Mn
Mar 31, 2021 67.20 Mn
Dec 31, 2020 -105.10 Mn
Sep 30, 2020 80.56 Mn
Jun 30, 2020 82.44 Mn
Mar 31, 2020 666,000.00
Dec 31, 2019 -224,000.00