LENZ Therapeutics LENZ
NASDAQ LENZ
$4.71 +0.05 (+1.07%)
As of: Aug 21, 2026 · 3:51 PM EDT

LENZ Therapeutics (LENZ) Return on Capital Employed (2021 - 2026)

LENZ Therapeutics (LENZ) posted quarterly Return on Capital Employed of 44.93% for Q1 2026, down 1516.0% year-over-year from 3.17% in Q1 2025, and down 16.89% quarter-over-quarter from 38.44% in Q4 2025.

LENZ Therapeutics (LENZ) Return on Capital Employed (2021 - 2026) Analysis & Trends

LENZ Therapeutics (LENZ) has reported Return on Capital Employed for 6 consecutive years, with 44.93% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Capital Employed fell 1516.0% year-over-year to 44.93%; the TTM figure through Mar 2026 stood at 44.93% (down 1516.0% YoY), while the FY2025 annual figure was 38.07%, up 619.0% from the prior year.
  • Return on Capital Employed fell to 44.93% in Q1 2026 per LENZ's latest filing, from 38.44% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 20.4% in Q1 2022 and bottomed at 60.74% in Q1 2024.
  • Historically, Return on Capital Employed has averaged 34.18% across 5 years, with a median of 31.15% in 2025.
  • Annual changes were most pronounced in 2024 — Return on Capital Employed slumped 3014 bps — and 2025, when it soared 3097 bps.
  • LENZ Therapeutics' Return on Capital Employed stood at 33.5% in 2022, then tumbled by 44 bps to 48.35% in 2023, then jumped by 42 bps to 28.01% in 2024, then sank by 37 bps to 38.44% in 2025, then fell by 17 bps to 44.93% in 2026.
  • Business Quant data shows LENZ's Return on Capital Employed at 44.93% in Q1 2026, 38.44% in Q4 2025, and 34.34% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 139.03 Bn 131.18 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 85.64 Bn 77.64 Bn 3.93 Bn 10.74%
3 Argenx Se 64.93 Bn 59.75 Bn 1.37 Bn -
4 Moderna 57.93 Bn 52.80 Bn 52.00 Mn -38.20%
5 BeOne Medicines 41.95 Bn 36.86 Bn 1.53 Bn 13.68%
6 Alnylam Pharmaceuticals 31.51 Bn 28.20 Bn 992.69 Mn 26.09%
7 BioNTech SE 28.00 Bn 9.60 Bn 668.28 Mn -6.85%
8 Insmed 27.42 Bn 26.26 Bn 358.27 Mn -50.93%
9 Royalty Pharma 27.29 Bn 26.45 Bn - 7.88%
10 LENZ Therapeutics 147.46 Mn 147.46 Mn 5.21 Mn -57.15%

Historic Data

Download Data
DateValue
Jun 30, 2026 -57.15%
Mar 31, 2026 -44.93%
Dec 31, 2025 -38.44%
Sep 30, 2025 -34.34%
Jun 30, 2025 -31.15%
Mar 31, 2025 -29.77%
Dec 31, 2024 -28.01%
Sep 30, 2024 -33.25%
Jun 30, 2024 -37.39%
Mar 31, 2024 -60.74%
Dec 31, 2023 -48.35%
Sep 30, 2023 -28.09%
Jun 30, 2023 -28.12%
Mar 31, 2023 -30.60%
Dec 31, 2022 -33.50%
Sep 30, 2022 -29.57%
Jun 30, 2022 -24.36%
Mar 31, 2022 -20.40%
Dec 31, 2021 -15.23%
Sep 30, 2021 -12.76%