Legend Biotech (LEGN) Research & Development (2019 - 2025)
Legend Biotech (LEGN) posted Research & Development of -$101.3 million for Q4 2025, up 10.47% on a QoQ basis from -$113.1 million in Q3 2025, and up 2.97% year-over-year from -$98.4 million in Q4 2024.
Legend Biotech (LEGN) Research & Development (2019 - 2025) Analysis & Trends
Legend Biotech's Research & Development history runs 7 years deep, the most recent figure standing at -$101.3 million for Q4 2025.
- Quarterly Research & Development rose 2.97% year-over-year to -$101.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$414.7 million (changed 0.28% YoY) and the FY2025 annual result came in at -$414.7 million, changed 0.29% from the prior year.
- Research & Development was -$101.3 million for Q4 2025 at Legend Biotech, up from -$113.1 million in the prior quarter.
- Across five years, Research & Development topped out at -$71072.0 in Q1 2021 and bottomed at -$154.5 million in Q2 2021.
- A 5-year average of -$87.7 million and a median of -$95.8 million in 2023 frame the typical range for Research & Development.
- Annual changes were most pronounced in 2022 — Research & Development plunged 114639.98% — and 2023, when it jumped 99.87%.
- Legend Biotech's Research & Development stood at -$86.5 million in 2021, then increased by 6.64% to -$80.8 million in 2022, then soared by 99.87% to -$105683.0 in 2023, then plunged by 98685.99% to -$104.4 million in 2024, then grew by 2.97% to -$101.3 million in 2025.
- Business Quant data shows LEGN's Research & Development at -$101.3 million in Q4 2025, -$113.1 million in Q3 2025, and -$98.3 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -17.94 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 1.46 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 541.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 961.60 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 1.54 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 15.66 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -443.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 343.97 Mn |
| 10 | Legend Biotech | 8.26 Bn | 7.36 Bn | - | -101.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -101.30 Mn |
| Sep 30, 2025 | -113.15 Mn |
| Jun 30, 2025 | -98.30 Mn |
| Mar 31, 2025 | -101.92 Mn |
| Dec 31, 2024 | -104.40 Mn |
| Sep 30, 2024 | -95.52 Mn |
| Jun 30, 2024 | -112.63 Mn |
| Mar 31, 2024 | -100.96 Mn |
| Dec 31, 2023 | -105,683.00 |
| Sep 30, 2023 | -95.86 Mn |
| Jun 30, 2023 | -95.79 Mn |
| Mar 31, 2023 | -84.89 Mn |
| Dec 31, 2022 | -80.76 Mn |
| Sep 30, 2022 | -104.52 Mn |
| Jun 30, 2022 | -68.83 Mn |
| Mar 31, 2022 | -81.55 Mn |
| Dec 31, 2021 | -86.50 Mn |
| Sep 30, 2021 | -72.31 Mn |
| Jun 30, 2021 | -154.46 Mn |
| Mar 31, 2021 | -71,072.00 |