Growth Metrics

Legend Biotech (LEGN) Net Margin (2019 - 2025)

Legend Biotech (LEGN) posted Net Margin of 0.82% for Q4 2025, up 105.78% on a QoQ basis from 14.12% in Q3 2025, and down 3082.0% year-over-year from 0.03% in Q4 2024.

Legend Biotech (LEGN) has 7 years of Net Margin data on file, last reported at 0.82% in Q4 2025.

  • In Q4 2025, Net Margin fell 3082.0% year-over-year to 0.82%; the TTM figure through Dec 2025 stood at 25.38% (up 3413.0% YoY), while the FY2025 annual figure was 3.22%, down 2688.0% from the prior year.
  • Net Margin climbed to 0.82% in Q4 2025, from 14.12% in the prior quarter.
  • Across five years, Net Margin topped out at 31.64% in Q4 2024 and bottomed at 1614.13% in Q2 2022.
  • A 5-year average of 246.31% and a median of 92.49% in 2024 frame the typical range for Net Margin.
  • Annual changes were most pronounced in 2022 — Net Margin tumbled 116149 bps — and 2023, when it soared 134258 bps.
  • Year by year, Net Margin stood at 226.53% in 2021, then slumped by 117 bps to 491.72% in 2022, then surged by 100 bps to 0.0% in 2023, then surged by 17358954 bps to 31.64% in 2024, then sank by 97 bps to 0.82% in 2025.
  • The last three Net Margin figures came in at 0.82% (Q4 2025), 14.12% (Q3 2025), and 48.7% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.82%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 34.53%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 20.17%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.65%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 0.82%
Sep 30, 2025 -14.12%
Jun 30, 2025 -48.70%
Mar 31, 2025 -51.74%
Dec 31, 2024 31.64%
Sep 30, 2024 -78.23%
Jun 30, 2024 -106.76%
Mar 31, 2024 -114.68%
Dec 31, 2023 0.00%
Sep 30, 2023 -64.79%
Jun 30, 2023 -271.55%
Mar 31, 2023 -308.51%
Dec 31, 2022 -491.72%
Sep 30, 2022 -310.50%
Jun 30, 2022 -1,614.13%
Mar 31, 2022 -64.53%
Dec 31, 2021 -226.53%
Sep 30, 2021 -738.96%
Jun 30, 2021 -452.65%
Mar 31, 2021 -0.66%
Dec 31, 2020 -141.79%
Sep 30, 2020 -566.49%
Jun 30, 2020 -1,162.72%
Mar 31, 2020 -383.06%
Dec 31, 2019 -328.76%
Sep 30, 2019 -157.28%
Jun 30, 2019 -285.54%