Legend Biotech (LEGN) Net Margin (2019 - 2025)
Legend Biotech (LEGN) posted Net Margin of 10.09% for Q4 2025, up 28.56% on a QoQ basis from 14.12% in Q3 2025, and up 2159.0% year-over-year from 0.45% in Q4 2024.
Legend Biotech (LEGN) Net Margin (2019 - 2025) Analysis & Trends
Legend Biotech's Net Margin history runs 7 years deep, the most recent figure standing at 10.09% for Q4 2025.
- Quarterly Net Margin rose 2159.0% year-over-year to 10.09% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 28.63% (up 1321.0% YoY) and the FY2025 annual result came in at 28.85%, up 125.0% from the prior year.
- Net Margin was 10.09% for Q4 2025 at Legend Biotech, up from 14.12% in the prior quarter.
- Across five years, Net Margin topped out at 852.93% in Q2 2021 and bottomed at 1614.13% in Q2 2022.
- A 5-year average of 177.35% and a median of 64.07% in 2022 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2021 — Net Margin soared 201566 bps — and 2022, when it plunged 246707 bps.
- Legend Biotech's Net Margin stood at 226.53% in 2021, then sank by 117 bps to 491.72% in 2022, then soared by 100 bps to 0.11% in 2023, then sank by 28331 bps to 31.68% in 2024, then soared by 68 bps to 10.09% in 2025.
- Business Quant data shows LEGN's Net Margin at 10.09% in Q4 2025, 14.12% in Q3 2025, and 48.7% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 15.02% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 28.20% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Legend Biotech | 8.26 Bn | 7.36 Bn | - | -10.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -10.09% |
| Sep 30, 2025 | -14.12% |
| Jun 30, 2025 | -48.70% |
| Mar 31, 2025 | -51.74% |
| Dec 31, 2024 | -31.68% |
| Sep 30, 2024 | -78.23% |
| Jun 30, 2024 | -9.76% |
| Mar 31, 2024 | -63.62% |
| Dec 31, 2023 | -0.11% |
| Sep 30, 2023 | -64.79% |
| Jun 30, 2023 | -271.55% |
| Mar 31, 2023 | -308.51% |
| Dec 31, 2022 | -491.72% |
| Sep 30, 2022 | -310.50% |
| Jun 30, 2022 | -1,614.13% |
| Mar 31, 2022 | -64.53% |
| Dec 31, 2021 | -226.53% |
| Sep 30, 2021 | -738.96% |
| Jun 30, 2021 | 852.93% |
| Mar 31, 2021 | -0.66% |