Growth Metrics

Legend Biotech (LEGN) Net Cash Flow (2019 - 2025)

Legend Biotech (LEGN) posted Net Cash Flow of $625.7 million for Q4 2025, up 6507.18% on a QoQ basis from $9.5 million in Q3 2025, and up 467.41% year-over-year from $110.3 million in Q4 2024.

Legend Biotech (LEGN) has 7 years of Net Cash Flow data on file, last reported at $625.7 million in Q4 2025.

  • In Q4 2025, Net Cash Flow rose 467.41% year-over-year to $625.7 million; the TTM figure through Dec 2025 stood at $609.2 million (up 161.6% YoY), while the FY2025 annual figure was $609.1 million, up 161.59% from the prior year.
  • Net Cash Flow climbed to $625.7 million in Q4 2025, from $9.5 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $625.7 million in Q4 2025 and bottomed at -$696.3 million in Q2 2024.
  • A 5-year average of -$4.0 million and a median of -$56.8 million in 2021 frame the typical range for Net Cash Flow.
  • Annual changes were most pronounced in 2022 — Net Cash Flow slumped 611.55% — and 2023, when it soared 19899.89%.
  • Year by year, Net Cash Flow stood at -$69.9 million in 2021, then slumped by 84.4% to -$128.9 million in 2022, then soared by 342.72% to $312.8 million in 2023, then plunged by 154.45% to -$170.3 million in 2024, then surged by 467.41% to $625.7 million in 2025.
  • The last three Net Cash Flow figures came in at $625.7 million (Q4 2025), $9.5 million (Q3 2025), and -$179.6 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 457.40 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -152.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 60.68 Mn
10 Revolution Medicines 32.39 Bn 32.39 Bn - 57.19 Mn

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 625.70 Mn
Dec 31, 2025 625.70 Mn
Sep 30, 2025 9.47 Mn
Sep 30, 2025 9.47 Mn
Jun 30, 2025 -179.56 Mn
Jun 30, 2025 -179.56 Mn
Mar 31, 2025 153.55 Mn
Mar 31, 2025 153.55 Mn
Dec 31, 2024 -170.30 Mn
Dec 31, 2024 -170.30 Mn
Sep 30, 2024 257.50 Mn
Sep 30, 2024 257.50 Mn
Jun 30, 2024 -696.33 Mn
Jun 30, 2024 -696.33 Mn
Mar 31, 2024 -379.80 Mn
Mar 31, 2024 -379.80 Mn
Dec 31, 2023 312.79 Mn
Dec 31, 2023 312.79 Mn
Sep 30, 2023 -268.96 Mn
Sep 30, 2023 -268.96 Mn
Jun 30, 2023 570.80 Mn
Jun 30, 2023 570.80 Mn
Mar 31, 2023 -123.63 Mn
Mar 31, 2023 -123.63 Mn
Dec 31, 2022 -128.87 Mn
Dec 31, 2022 -128.87 Mn
Sep 30, 2022 433.50 Mn
Sep 30, 2022 433.50 Mn
Jun 30, 2022 2.85 Mn
Jun 30, 2022 2.85 Mn
Mar 31, 2022 -311.16 Mn
Mar 31, 2022 -311.16 Mn
Dec 31, 2021 -69.89 Mn
Dec 31, 2021 -69.89 Mn
Sep 30, 2021 -149.12 Mn
Sep 30, 2021 -149.12 Mn
Jun 30, 2021 75.47 Mn
Jun 30, 2021 75.47 Mn
Mar 31, 2021 -43.73 Mn
Mar 31, 2021 -43.73 Mn
Dec 31, 2020 -246.51 Mn
Dec 31, 2020 -246.51 Mn
Sep 30, 2020 -113.34 Mn
Sep 30, 2020 -113.34 Mn
Jun 30, 2020 393.71 Mn
Jun 30, 2020 393.71 Mn
Mar 31, 2020 85.46 Mn
Mar 31, 2020 85.46 Mn
Dec 31, 2019 46.78 Mn
Dec 31, 2019 46.78 Mn
Sep 30, 2019 -1.40 Mn
Sep 30, 2019 -1.40 Mn
Jun 30, 2019 -81.97 Mn
Jun 30, 2019 -81.97 Mn