Growth Metrics

Legend Biotech (LEGN) Free Cash Flow (2019 - 2025)

Legend Biotech (LEGN) posted Free Cash Flow of -$12.2 million for Q4 2025, down 136.09% on a QoQ basis from $33.8 million in Q3 2025, and up 88.7% year-over-year from -$6.5 million in Q4 2024.

Legend Biotech (LEGN) has 7 years of Free Cash Flow data on file, last reported at -$12.2 million in Q4 2025.

  • In Q4 2025, Free Cash Flow rose 88.7% year-over-year to -$12.2 million; the TTM figure through Dec 2025 stood at -$84.0 million (up 46.91% YoY), while the FY2025 annual figure was -$100.2 million, up 36.62% from the prior year.
  • Free Cash Flow eased to -$12.2 million in Q4 2025, from $33.8 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $33.8 million in Q3 2025 and bottomed at -$156.3 million in Q4 2021.
  • A 5-year average of -$53.3 million and a median of -$49.8 million in 2021 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2023 — Free Cash Flow plunged 8513.94% — and 2025, when it jumped 145.83%.
  • Year by year, Free Cash Flow stood at -$156.3 million in 2021, then soared by 81.56% to -$28.8 million in 2022, then slumped by 356.25% to -$131.5 million in 2023, then gained by 17.9% to -$107.9 million in 2024, then jumped by 88.7% to -$12.2 million in 2025.
  • The last three Free Cash Flow figures came in at -$12.2 million (Q4 2025), $33.8 million (Q3 2025), and -$3.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 48.67 Mn
10 Revolution Medicines 32.39 Bn 32.39 Bn - -354.95 Mn

Historic Data

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DateValue
Dec 31, 2025 -12.20 Mn
Dec 31, 2025 -12.20 Mn
Sep 30, 2025 33.81 Mn
Sep 30, 2025 33.81 Mn
Jun 30, 2025 -3.82 Mn
Jun 30, 2025 -3.82 Mn
Mar 31, 2025 -101.75 Mn
Mar 31, 2025 -101.75 Mn
Dec 31, 2024 -107.93 Mn
Dec 31, 2024 -107.93 Mn
Sep 30, 2024 -73.76 Mn
Sep 30, 2024 -73.76 Mn
Jun 30, 2024 1.77 Mn
Jun 30, 2024 1.77 Mn
Mar 31, 2024 21.76 Mn
Mar 31, 2024 21.76 Mn
Dec 31, 2023 -131.47 Mn
Dec 31, 2023 -131.47 Mn
Sep 30, 2023 -55.47 Mn
Sep 30, 2023 -55.47 Mn
Jun 30, 2023 -91.48 Mn
Jun 30, 2023 -91.48 Mn
Mar 31, 2023 -134.94 Mn
Mar 31, 2023 -134.94 Mn
Dec 31, 2022 -28.82 Mn
Dec 31, 2022 -28.82 Mn
Sep 30, 2022 -69.53 Mn
Sep 30, 2022 -69.53 Mn
Jun 30, 2022 -1.06 Mn
Jun 30, 2022 -1.06 Mn
Mar 31, 2022 -66.57 Mn
Mar 31, 2022 -66.57 Mn
Dec 31, 2021 -156.27 Mn
Dec 31, 2021 -156.27 Mn
Sep 30, 2021 -33.11 Mn
Sep 30, 2021 -33.11 Mn
Jun 30, 2021 -44.09 Mn
Jun 30, 2021 -44.09 Mn
Mar 31, 2021 -11.38 Mn
Mar 31, 2021 -11.38 Mn
Dec 31, 2020 -196.75 Mn
Dec 31, 2020 -196.75 Mn
Sep 30, 2020 -57.28 Mn
Sep 30, 2020 -57.28 Mn
Jun 30, 2020 -56.89 Mn
Jun 30, 2020 -56.89 Mn
Mar 31, 2020 -45.80 Mn
Mar 31, 2020 -45.80 Mn
Dec 31, 2019 -59.99 Mn
Dec 31, 2019 -59.99 Mn
Sep 30, 2019 19.95 Mn
Sep 30, 2019 19.95 Mn
Jun 30, 2019 -38.77 Mn
Jun 30, 2019 -38.77 Mn