Growth Metrics

Legend Biotech (LEGN) EBT Margin (2019 - 2025)

Legend Biotech (LEGN) posted EBT Margin of 6.4% for Q4 2025, up 55.4% on a QoQ basis from 14.35% in Q3 2025, and down 2817.0% year-over-year from 0.24% in Q4 2024.

Legend Biotech (LEGN) has 7 years of EBT Margin data on file, last reported at 6.4% in Q4 2025.

  • In Q4 2025, EBT Margin fell 2817.0% year-over-year to 6.4%; the TTM figure through Dec 2025 stood at 27.47% (down 2134.0% YoY), while the FY2025 annual figure was 27.47%, down 226.0% from the prior year.
  • EBT Margin grew to 6.4% in Q4 2025, from 14.35% in the prior quarter.
  • Across five years, EBT Margin topped out at 63.61% in Q1 2024 and bottomed at 1612.82% in Q2 2022.
  • A 5-year average of 233.09% and a median of 64.65% in 2023 frame the typical range for EBT Margin.
  • Annual changes were most pronounced in 2022 — EBT Margin tumbled 116018 bps — and 2023, when it soared 134167 bps.
  • Year by year, EBT Margin stood at 226.53% in 2021, then slumped by 117 bps to 491.16% in 2022, then surged by 100 bps to 0.18% in 2023, then soared by 11883 bps to 21.77% in 2024, then sank by 129 bps to 6.4% in 2025.
  • The last three EBT Margin figures came in at 6.4% (Q4 2025), 14.35% (Q3 2025), and 48.93% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.40%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 41.95%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 23.05%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 18.99%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -6.43%
Sep 30, 2025 -14.35%
Jun 30, 2025 -48.93%
Mar 31, 2025 50.82%
Dec 31, 2024 21.77%
Sep 30, 2024 -75.46%
Jun 30, 2024 -9.63%
Mar 31, 2024 63.61%
Dec 31, 2023 0.00%
Sep 30, 2023 -65.09%
Jun 30, 2023 -271.16%
Mar 31, 2023 308.16%
Dec 31, 2022 -491.16%
Sep 30, 2022 -309.94%
Jun 30, 2022 -1,612.82%
Mar 31, 2022 -64.20%
Dec 31, 2021 -226.53%
Sep 30, 2021 -738.96%
Jun 30, 2021 -452.64%
Mar 31, 2021 -0.69%
Dec 31, 2020 -141.62%
Sep 30, 2020 -570.82%
Jun 30, 2020 -1,162.72%
Mar 31, 2020 -415.18%
Dec 31, 2019 -317.13%
Sep 30, 2019 -157.25%
Jun 30, 2019 -282.20%