Growth Metrics

Krystal Biotech (KRYS) Return on Sales (2021 - 2025)

Krystal Biotech (KRYS) has disclosed Return on Sales for 4 consecutive years, with 0.48% as the latest value for Q4 2025.

  • Quarterly Return on Sales fell 2.0% to 0.48% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 0.53% through Dec 2025, up 22.0% year-over-year, with the annual reading at 0.53% for FY2025, 22.0% up from the prior year.
  • Return on Sales hit 0.48% in Q4 2025 for Krystal Biotech, down from 0.81% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 46.63% in Q4 2021 to a low of 0.02% in Q1 2024.
  • Historically, Return on Sales has averaged 5.84% across 4 years, with a median of 0.44% in 2025.
  • Biggest five-year swings in Return on Sales: plummeted -911bps in 2024 and later skyrocketed 49bps in 2025.
  • Year by year, Return on Sales stood at 46.63% in 2021, then crashed by -100bps to 0.21% in 2023, then surged by 142bps to 0.5% in 2024, then dropped by -4bps to 0.48% in 2025.
  • Business Quant data shows Return on Sales for KRYS at 0.48% in Q4 2025, 0.81% in Q3 2025, and 0.4% in Q2 2025.