Growth Metrics

Krystal Biotech (KRYS) Return on Sales (2021 - 2025)

Krystal Biotech's Return on Sales history spans 4 years, with the latest figure at 0.48% for Q4 2025.

  • For Q4 2025, Return on Sales fell 2.0% year-over-year to 0.48%; the TTM value through Dec 2025 reached 0.53%, up 22.0%, while the annual FY2025 figure was 0.53%, 22.0% up from the prior year.
  • Return on Sales for Q4 2025 was 0.48% at Krystal Biotech, down from 0.81% in the prior quarter.
  • Across five years, Return on Sales topped out at 46.63% in Q4 2021 and bottomed at 0.02% in Q1 2024.
  • The 4-year median for Return on Sales is 0.44% (2025), against an average of 5.84%.
  • The largest annual shift saw Return on Sales crashed -911bps in 2024 before it soared 49bps in 2025.
  • A 4-year view of Return on Sales shows it stood at 46.63% in 2021, then plummeted by -100bps to 0.21% in 2023, then skyrocketed by 142bps to 0.5% in 2024, then fell by -4bps to 0.48% in 2025.
  • Per Business Quant, the three most recent readings for KRYS's Return on Sales are 0.48% (Q4 2025), 0.81% (Q3 2025), and 0.4% (Q2 2025).