Krystal Biotech KRYS Institutional Ownership

NASDAQ KRYS

$357.99 -13.48 (-3.63%)

As of: Sep 4, 2026 · 3:59 PM EDT

Institutions by Trading Activity

423 Institutions

Increased 272 64.3%

Unchanged 45 10.6%

Reduced 106 25.1%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

103.31%

▲+5.61 pp QoQ

Shares Held by Institutions

30.51Mn

of 29.53Mn outstanding

▲+9.33% QoQ

Shares Outstanding

29.53Mn

-978.40K held outside 13F filers

Institutional Investors

423

filed 13F for Jun 2026

▲+57 vs prior quarter

Net Shares Added (QoQ)

+2.60Mn

accumulated since last quarter

Value of Holdings

$11.33Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Krystal Biotech, Inc. (NASDAQ:KRYS) has 423 institutional investors that have filed 13F reports for the period ending June 2026.

These investors collectively held 103.3% of Krystal Biotech's outstanding shares in June 2026, up from 97.7% in March 2026.
They increased total shares held in Krystal Biotech by 9.33% from the prior quarter, while the number of investors in KRYS increased 54.38% year over year.
Among the 423 funds, 272 bought more Krystal Biotech shares, 106 sold down, and 45 held their ground.
The aggregate institutional position in Krystal Biotech amounted to 30.51Mn shares as of June 2026, up by 2.6Mn shares quarter on quarter, and up 2.86Mn shares year over year.
FMR LLC holds the largest position in KRYS at 4.42Mn shares as of June 30, 2026, or 14.96% of shares outstanding.
The biggest buyers of Krystal Biotech for the quarter ending June 2026 included VESTOR CAPITAL, LLC (700.71K), NORGES BANK (259.03K), Jupiter Topco LLC (256.67K), Sixth Street Partners Management Company, L.P. (254.83K), BlackRock, Inc. (240.98K).
The largest sales of KRYS for the quarter ending June 2026 came from Bellevue Group AG (404.26K), Soleus Capital Management, L.P. (213.83K), S SQUARED TECHNOLOGY, LLC (94.88K), BRAIDWELL LP (53.45K), Capital World Investors (46.88K).
Business Quant data shows the 10 biggest positions in Krystal Biotech as of June 2026 are held by FMR LLC (4.42Mn), BlackRock, Inc. (4.18Mn), Avoro Capital Advisors LLC (2.89Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (1.57Mn), State Street Corp (1.35Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.24Mn), Soleus Capital Management, L.P. (939.25K), Capital World Investors (777.84K), VESTOR CAPITAL, LLC (700.91K), GEODE CAPITAL MANAGEMENT, LLC (698.99K).

Form 13F Holdings

423 Institutional Holders

Report period 30 Jun, 2026

Total shares held 30.51Mn

Of outstanding 103.31%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	4,418,197	14.96%	▲44,210	+1.01%	$1.64Bn
2	BlackRock, Inc.	0002012383	4,181,432	14.16%	▲240,976	+6.12%	$1.55Bn
3	Avoro Capital Advisors LLC	0001633313	2,888,888	9.78%	0	0.00%	$1.07Bn
4	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	1,574,905	5.33%	▲118,178	+8.11%	$585.34Mn
5	State Street Corp	0000093751	1,351,158	4.58%	▲36,724	+2.79%	$502.20Mn
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	1,240,567	4.20%	▲75,243	+6.46%	$461.08Mn
7	Soleus Capital Management, L.P.	0001802630	939,254	3.18%	▼213,833	-18.54%	$349.09Mn
8	Capital World Investors	0001422849	777,843	2.63%	▼46,877	-5.68%	$289.10Mn
9	VESTOR CAPITAL, LLC	0001132699	700,914	2.37%	▲700,714	+350,357.00%	$78.19K
10	GEODE CAPITAL MANAGEMENT, LLC	0001214717	698,993	2.37%	▲55,018	+8.54%	$259.84Mn
11	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	687,400	2.33%	▲202,326	+41.71%	$255.49K
12	Hood River Capital Management LLC	0001578177	663,375	2.25%	▲43,789	+7.07%	$246.56Mn
13	Redmile Group, LLC	0001425738	632,005	2.14%	▼41,500	-6.16%	$234.90Mn
14	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0001644956	570,153	1.93%	▲162,975	+40.03%	$211.91Mn
15	Frazier Life Sciences Management, L.P.	0001892134	481,307	1.63%	0	0.00%	$178.89Mn
16	DIMENSIONAL FUND ADVISORS LP	0000354204	476,038	1.61%	▲7,048	+1.50%	$176.94Mn
17	FIRST TRUST ADVISORS LP	0001125816	324,900	1.10%	▼25,621	-7.31%	$120.76Mn
18	Invesco Ltd.	0000914208	324,755	1.10%	▲73,382	+29.19%	$120.70Mn
19	Goldman Sachs Group Inc	0000886982	298,841	1.01%	▲83,892	+39.03%	$111.07Mn
20	Northern Trust Corp	0000073124	283,784	0.96%	▲31,321	+12.41%	$105.47Mn

Showing 1 to 20 of 423 holders