Krystal Biotech (KRYS) Return on Capital Employed (2017 - 2026)

Krystal Biotech (KRYS) reported Return on Capital Employed of 14.21% for Q1 2026, up 318.0% on a YoY basis from 3.4% in Q1 2025, and up 4.33% sequentially from 13.62% in Q4 2025.

Krystal Biotech (KRYS) Return on Capital Employed (2017 - 2026) Analysis & Trends

Krystal Biotech (KRYS) has 10 years of Return on Capital Employed data on file, last reported at 14.21% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed rose 318.0% year-over-year to 14.21%; the trailing twelve-month figure through Mar 2026 stood at 14.21% (up 318.0% YoY), and the FY2025 full-year result was 14.77%, up 690.0% from the prior year.
  • Return on Capital Employed advanced to 14.21% in Q1 2026, from 13.62% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 14.42% in Q3 2025 to a low of 28.19% in Q1 2023.
  • A 5-year average of 6.62% and a median of 8.56% in 2024 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed plunged 1365 bps in 2022 and soared 2401 bps in 2024, its largest moves.
  • Tracing KRYS's Return on Capital Employed over 5 years: stood at 26.96% in 2022, then soared by 47 bps to 14.21% in 2023, then surged by 150 bps to 7.17% in 2024, then surged by 90 bps to 13.62% in 2025, then increased by 4 bps to 14.21% in 2026.
  • Business Quant data shows KRYS's Return on Capital Employed at 14.21% in Q1 2026, 13.62% in Q4 2025, and 14.42% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -31.80%
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -107.40%
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 10.46%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 10.19%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -68.84%
10 Krystal Biotech 9.84 Bn 9.02 Bn 110.08 Mn 14.21%

Historic Data

Download Data
DateValue
Mar 31, 2026 14.21%
Dec 31, 2025 13.62%
Sep 30, 2025 14.42%
Jun 30, 2025 13.67%
Mar 31, 2025 11.02%
Dec 31, 2024 7.17%
Sep 30, 2024 3.21%
Jun 30, 2024 -2.56%
Mar 31, 2024 -8.56%
Dec 31, 2023 -14.21%
Sep 30, 2023 -20.81%
Jun 30, 2023 -26.21%
Mar 31, 2023 -28.19%
Dec 31, 2022 -26.96%
Sep 30, 2022 -23.59%
Jun 30, 2022 -20.27%
Mar 31, 2022 -18.56%
Dec 31, 2021 -13.31%
Sep 30, 2021 -13.81%
Jun 30, 2021 -11.96%