Krystal Biotech (KRYS) Return on Capital Employed (2017 - 2026)

Krystal Biotech's (KRYS) quarterly Return on Capital Employed came in at 14.21% in Q1 2026, up 318.0% year-on-year from 3.4% in Q1 2025, and up 4.33% quarter-over-quarter from 13.62% in Q4 2025.

Krystal Biotech (KRYS) Return on Capital Employed (2017 - 2026) Analysis & Trends

Krystal Biotech has disclosed Return on Capital Employed across 10 years of filings, most recently posting 14.21% for Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 14.21%, up 318.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 14.21% (up 318.0% YoY), and the FY2025 annual result was 14.77%, up 690.0% from the prior year.
  • Return on Capital Employed came in at 14.21% for Q1 2026 at Krystal Biotech, up from 13.62% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 14.42% in Q3 2025 to a low of 28.19% in Q1 2023.
  • The 5-year median for Return on Capital Employed is 8.56% (2024), against an average of 6.62%.
  • Across the five-year window, Return on Capital Employed slumped 1365 bps in 2022 and soared 2401 bps in 2024, its largest moves.
  • Krystal Biotech's Return on Capital Employed stood at 26.96% in 2022, then jumped by 47 bps to 14.21% in 2023, then soared by 150 bps to 7.17% in 2024, then soared by 90 bps to 13.62% in 2025, then rose by 4 bps to 14.21% in 2026.
  • The last three Return on Capital Employed figures came in at 14.21% (Q1 2026), 13.62% (Q4 2025), and 14.42% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 14.21%

Historic Data

Download Data
DateValue
Mar 31, 2026 14.21%
Dec 31, 2025 13.62%
Sep 30, 2025 14.42%
Jun 30, 2025 13.67%
Mar 31, 2025 11.02%
Dec 31, 2024 7.17%
Sep 30, 2024 3.21%
Jun 30, 2024 -2.56%
Mar 31, 2024 -8.56%
Dec 31, 2023 -14.21%
Sep 30, 2023 -20.81%
Jun 30, 2023 -26.21%
Mar 31, 2023 -28.19%
Dec 31, 2022 -26.96%
Sep 30, 2022 -23.59%
Jun 30, 2022 -20.27%
Mar 31, 2022 -18.56%
Dec 31, 2021 -13.31%
Sep 30, 2021 -13.81%
Jun 30, 2021 -11.96%