Krystal Biotech (KRYS) EBITDA (2016 - 2026)

Krystal Biotech's (KRYS) quarterly EBITDA came in at $53.2 million in Q1 2026, up 46.43% year-on-year from $36.3 million in Q1 2025, and up 3.38% quarter-over-quarter from $51.4 million in Q4 2025.

Krystal Biotech (KRYS) EBITDA (2016 - 2026) Analysis & Trends

Krystal Biotech has disclosed EBITDA across 11 years of filings, most recently posting $53.2 million for Q1 2026.

  • EBITDA for Q1 2026 came in at $53.2 million, up 46.43% year-over-year; the trailing twelve-month figure through Mar 2026 was $223.0 million (up 78.92% YoY), and the FY2025 annual result was $206.2 million, up 133.39% from the prior year.
  • EBITDA came in at $53.2 million for Q1 2026 at Krystal Biotech, up from $51.4 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $80.6 million in Q3 2023 to a low of -$51.0 million in Q1 2022.
  • The 5-year median for EBITDA is $15.2 million (2024), against an average of $12.9 million.
  • Across the five-year window, EBITDA slumped 222.47% in 2022 and soared 726360.0% in 2025, its largest moves.
  • Krystal Biotech's EBITDA stood at -$31.3 million in 2022, then surged by 131.02% to $9.7 million in 2023, then jumped by 350.75% to $43.8 million in 2024, then grew by 17.5% to $51.4 million in 2025, then grew by 3.38% to $53.2 million in 2026.
  • The last three EBITDA figures came in at $53.2 million (Q1 2026), $51.4 million (Q4 2025), and $79.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 53.17 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 53.17 Mn
Dec 31, 2025 51.44 Mn
Sep 30, 2025 79.31 Mn
Jun 30, 2025 39.10 Mn
Mar 31, 2025 36.31 Mn
Dec 31, 2024 43.78 Mn
Sep 30, 2024 29.33 Mn
Jun 30, 2024 15.23 Mn
Mar 31, 2024 -5,000.00
Dec 31, 2023 9.71 Mn
Sep 30, 2023 80.60 Mn
Jun 30, 2023 -33.29 Mn
Mar 31, 2023 -44.72 Mn
Dec 31, 2022 -31.31 Mn
Sep 30, 2022 -29.78 Mn
Jun 30, 2022 -28.46 Mn
Mar 31, 2022 -51.00 Mn
Dec 31, 2021 -21.96 Mn
Sep 30, 2021 -15.58 Mn
Jun 30, 2021 -16.39 Mn