Growth Metrics

Krystal Biotech (KRYS) EBITDA (2016 - 2026)

Krystal Biotech recorded quarterly EBITDA of $53.2 million in Q1 2026, up 3.38% quarter-over-quarter from $51.4 million in Q4 2025, and up 46.43% year-over-year from $36.3 million in Q1 2025.

Krystal Biotech's EBITDA history runs 11 years deep, the most recent figure standing at $53.2 million for Q1 2026.

  • In Q1 2026, EBITDA rose 46.43% year-over-year to $53.2 million; the TTM figure through Mar 2026 stood at $223.0 million (up 78.92% YoY), while the FY2025 annual figure was $206.2 million, up 133.39% from the prior year.
  • EBITDA came in at $53.2 million for Q1 2026 at Krystal Biotech, up from $51.4 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $80.6 million in Q3 2023 to a low of -$51.0 million in Q1 2022.
  • A 5-year average of $12.9 million and a median of $15.2 million in 2024 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA sank 222.47% in 2022 and jumped 726360.0% in 2025, its largest moves.
  • Krystal Biotech's EBITDA stood at -$31.3 million in 2022, then soared by 131.02% to $9.7 million in 2023, then surged by 350.75% to $43.8 million in 2024, then increased by 17.5% to $51.4 million in 2025, then increased by 3.38% to $53.2 million in 2026.
  • According to Business Quant data, EBITDA over the past three periods registered $53.2 million, $51.4 million, and $79.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 Krystal Biotech 9.05 Bn 8.23 Bn 110.03 Mn 53.17 Mn

Historic Data

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DateValue
Mar 31, 2026 53.17 Mn
Dec 31, 2025 51.44 Mn
Sep 30, 2025 79.31 Mn
Jun 30, 2025 39.10 Mn
Mar 31, 2025 36.31 Mn
Dec 31, 2024 43.78 Mn
Sep 30, 2024 29.33 Mn
Jun 30, 2024 15.23 Mn
Mar 31, 2024 -5,000.00
Dec 31, 2023 9.71 Mn
Sep 30, 2023 80.60 Mn
Jun 30, 2023 -33.29 Mn
Mar 31, 2023 -44.72 Mn
Dec 31, 2022 -31.31 Mn
Sep 30, 2022 -29.78 Mn
Jun 30, 2022 -28.46 Mn
Mar 31, 2022 -51.00 Mn
Dec 31, 2021 -21.96 Mn
Sep 30, 2021 -15.58 Mn
Jun 30, 2021 -16.39 Mn
Mar 31, 2021 -15.82 Mn
Dec 31, 2020 -10.40 Mn
Sep 30, 2020 -9.63 Mn
Jun 30, 2020 -6.82 Mn
Mar 31, 2020 -5.33 Mn
Dec 31, 2019 -5.36 Mn
Sep 30, 2019 -4.28 Mn
Jun 30, 2019 -5.35 Mn
Mar 31, 2019 -4.10 Mn
Dec 31, 2018 -3.71 Mn
Sep 30, 2018 -2.75 Mn
Jun 30, 2018 -2.28 Mn
Mar 31, 2018 -2.15 Mn
Dec 31, 2017 -1.50 Mn
Sep 30, 2017 -5.27 Mn
Jun 30, 2017 -759,000.00
Mar 31, 2017 -465,000.00
Dec 31, 2016 -620,000.00
Sep 30, 2016 -322,000.00