Keros Therapeutics (KROS) Return on Sales (2019 - 2025)
Keros Therapeutics (KROS) posted Return on Sales of 1.25% for Q4 2025, down 24111.13% on a QoQ basis from 0.01% in Q3 2025, and down 110.0% year-over-year from 12.48% in Q4 2024.
Keros Therapeutics (KROS) Return on Sales (2019 - 2025) Analysis & Trends
Keros Therapeutics' Return on Sales history runs 7 years deep, the most recent figure standing at 1.25% for Q4 2025.
- Quarterly Return on Sales fell 110.0% year-over-year to 1.25% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.0% (up 54.0% YoY) and the FY2025 annual result came in at 0.0%, up 53.0% from the prior year.
- Return on Sales was 1.25% for Q4 2025 at Keros Therapeutics, down from 0.01% in the prior quarter.
- Across five years, Return on Sales topped out at 0.01% in Q1 2025 and bottomed at 96.1% in Q3 2023.
- A 5-year average of 7.31% and a median of 0.15% in 2024 frame the typical range for Return on Sales.
- Annual changes were most pronounced in 2023 — Return on Sales slumped 9608 bps — and 2024, when it jumped 9474 bps.
- Keros Therapeutics' Return on Sales stood at 0.0% in 2021, then sank by 1400 bps to 0.06% in 2022, then plunged by 5380 bps to 3.19% in 2023, then surged by 95 bps to 0.15% in 2024, then slumped by 725 bps to 1.25% in 2025.
- Business Quant data shows KROS's Return on Sales at 1.25% in Q4 2025, 0.01% in Q3 2025, and 0.02% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 0.00% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 0.00% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 0.00% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 0.00% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Keros Therapeutics | 374.82 Mn | 87.42 Mn | - | -1.25% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -1.25% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | -0.02% |
| Mar 31, 2025 | 0.01% |
| Dec 31, 2024 | -0.15% |
| Sep 30, 2024 | -1.36% |
| Jun 30, 2024 | -9.01% |
| Mar 31, 2024 | -5.19% |
| Dec 31, 2023 | -3.19% |
| Sep 30, 2023 | -96.10% |
| Dec 31, 2022 | -0.06% |
| Sep 30, 2022 | -0.02% |
| Jun 30, 2022 | -0.02% |
| Mar 31, 2022 | -0.01% |
| Dec 31, 2021 | 0.00% |
| Sep 30, 2021 | -6.25% |
| Jun 30, 2021 | -1.56% |
| Sep 30, 2020 | -0.15% |
| Jun 30, 2020 | -0.06% |
| Mar 31, 2020 | -0.03% |