Keros Therapeutics (KROS) Return on Sales (2019 - 2025)
Keros Therapeutics posted quarterly Return on Sales of 0.41% for Q4 2025, down 131.0% year-on-year from 1.31% in Q4 2024, and down 7865.62% on a QoQ basis from 0.01% in Q3 2025.
Keros Therapeutics (KROS) has 7 years of Return on Sales data on file, last reported at 0.41% in Q4 2025.
- For the quarter ending Q4 2025, Return on Sales fell 131.0% year-over-year to 0.41%; the trailing twelve-month figure through Dec 2025 stood at 0.0% (down 1561.0% YoY), and the FY2025 full-year result was 0.0%, changed N/A from the prior year.
- Return on Sales for Q4 2025 stood at 0.41%, down from 0.01% in the prior quarter.
- Across five years, Return on Sales topped out at 0.91% in Q4 2024 and bottomed at 54.1% in Q3 2023.
- The 5-year median for Return on Sales is 0.06% (2022), against an average of 5.26%.
- The widest annual swing landed in 2023, when Return on Sales tumbled 5408 bps; it then jumped 5274 bps in 2024.
- A 5-year view of Return on Sales shows it stood at 0.0% in 2021, then slumped by 1400 bps to 0.06% in 2022, then plunged by 5486 bps to 3.25% in 2023, then soared by 128 bps to 0.91% in 2024, then plunged by 145 bps to 0.41% in 2025.
- The last three Return on Sales figures came in at 0.41% (Q4 2025), 0.01% (Q3 2025), and 0.02% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.00% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 0.00% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 0.00% |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 0.00% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 0.00% |
| 10 | Keros Therapeutics | 403.85 Mn | 116.45 Mn | - | -0.41% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -0.41% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | -0.02% |
| Mar 31, 2025 | 0.01% |
| Dec 31, 2024 | 0.91% |
| Sep 30, 2024 | -1.36% |
| Jun 30, 2024 | -11.80% |
| Mar 31, 2024 | -11.54% |
| Dec 31, 2023 | -3.25% |
| Sep 30, 2023 | -54.10% |
| Dec 31, 2022 | -0.06% |
| Sep 30, 2022 | -0.02% |
| Jun 30, 2022 | -0.02% |
| Mar 31, 2022 | -0.01% |
| Dec 31, 2021 | 0.00% |
| Sep 30, 2021 | -6.25% |
| Jun 30, 2021 | -1.56% |
| Sep 30, 2020 | -0.15% |
| Jun 30, 2020 | -0.06% |
| Mar 31, 2020 | -0.03% |
| Dec 31, 2019 | -0.01% |
| Sep 30, 2019 | -0.01% |
| Jun 30, 2019 | -0.01% |
| Mar 31, 2019 | -0.01% |