Keros Therapeutics (KROS) Return on Capital Employed (2020 - 2025)

Keros Therapeutics (KROS) posted Return on Capital Employed of 12.99% for Q4 2025, up 116.41% on a QoQ basis from 6.0% in Q3 2025, and up 4997.0% year-over-year from 0.25% in Q4 2024.

Keros Therapeutics (KROS) Return on Capital Employed (2020 - 2025) Analysis & Trends

Keros Therapeutics' Return on Capital Employed history runs 6 years deep, the most recent figure standing at 12.99% for Q4 2025.

  • Quarterly Return on Capital Employed rose 4997.0% year-over-year to 12.99% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 12.99% (up 4997.0% YoY) and the FY2025 annual result came in at 14.8%, up 6009.0% from the prior year.
  • Return on Capital Employed was 12.99% for Q4 2025 at Keros Therapeutics, up from 6.0% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 12.99% in Q4 2025 and bottomed at 52.49% in Q4 2023.
  • A 5-year average of 28.5% and a median of 37.04% in 2022 frame the typical range for Return on Capital Employed.
  • Annual changes were most pronounced in 2022 — Return on Capital Employed slumped 1920 bps — and 2025, when it surged 4997 bps.
  • Keros Therapeutics' Return on Capital Employed stood at 24.43% in 2021, then tumbled by 79 bps to 43.63% in 2022, then declined by 20 bps to 52.49% in 2023, then climbed by 30 bps to 36.98% in 2024, then surged by 135 bps to 12.99% in 2025.
  • Business Quant data shows KROS's Return on Capital Employed at 12.99% in Q4 2025, 6.0% in Q3 2025, and 0.04% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Keros Therapeutics 377.42 Mn 90.02 Mn - 12.99%

Historic Data

Download Data
DateValue
Dec 31, 2025 12.99%
Sep 30, 2025 6.00%
Jun 30, 2025 0.04%
Mar 31, 2025 -1.56%
Dec 31, 2024 -36.98%
Sep 30, 2024 -41.80%
Jun 30, 2024 -42.00%
Mar 31, 2024 -43.88%
Dec 31, 2023 -52.49%
Sep 30, 2023 -47.89%
Jun 30, 2023 -39.56%
Mar 31, 2023 -39.23%
Dec 31, 2022 -43.63%
Sep 30, 2022 -38.45%
Jun 30, 2022 -37.09%
Mar 31, 2022 -27.72%
Dec 31, 2021 -24.43%
Sep 30, 2021 -28.71%
Jun 30, 2021 -23.27%
Mar 31, 2021 -20.39%