Keros Therapeutics (KROS) EBITDA (2019 - 2025)

Keros Therapeutics (KROS) posted EBITDA of -$29.3 million for Q4 2025, down 90.26% on a QoQ basis from -$15.4 million in Q3 2025, and up 45.04% year-over-year from -$20.2 million in Q4 2024.

Keros Therapeutics (KROS) EBITDA (2019 - 2025) Analysis & Trends

Keros Therapeutics' EBITDA history runs 7 years deep, the most recent figure standing at -$29.3 million for Q4 2025.

  • Quarterly EBITDA rose 45.04% year-over-year to -$29.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $67.6 million (up 132.05% YoY) and the FY2025 annual result came in at $67.6 million, up 132.05% from the prior year.
  • EBITDA was -$29.3 million for Q4 2025 at Keros Therapeutics, down from -$15.4 million in the prior quarter.
  • Across five years, EBITDA topped out at $152.0 million in Q1 2025 and bottomed at -$58.7 million in Q3 2024.
  • A 5-year average of -$24.2 million and a median of -$31.3 million in 2022 frame the typical range for EBITDA.
  • Annual changes were most pronounced in 2022 — EBITDA plunged 556.8% — and 2025, when it surged 413.59%.
  • Keros Therapeutics' EBITDA stood at -$4.9 million in 2021, then plunged by 556.8% to -$32.0 million in 2022, then plunged by 45.35% to -$46.5 million in 2023, then slipped by 14.64% to -$53.3 million in 2024, then surged by 45.04% to -$29.3 million in 2025.
  • Business Quant data shows KROS's EBITDA at -$29.3 million in Q4 2025, -$15.4 million in Q3 2025, and -$39.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Keros Therapeutics 374.82 Mn 87.42 Mn - -29.27 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -29.27 Mn
Sep 30, 2025 -15.38 Mn
Jun 30, 2025 -39.82 Mn
Mar 31, 2025 152.04 Mn
Dec 31, 2024 -53.25 Mn
Sep 30, 2024 -58.66 Mn
Jun 30, 2024 -50.44 Mn
Mar 31, 2024 -48.48 Mn
Dec 31, 2023 -46.46 Mn
Sep 30, 2023 -43.28 Mn
Jun 30, 2023 -41.34 Mn
Mar 31, 2023 -38.87 Mn
Dec 31, 2022 -31.96 Mn
Sep 30, 2022 -27.98 Mn
Jun 30, 2022 -30.73 Mn
Mar 31, 2022 -24.13 Mn
Dec 31, 2021 -4.87 Mn
Sep 30, 2021 -20.20 Mn
Jun 30, 2021 -15.54 Mn
Mar 31, 2021 -15.77 Mn