Karyopharm Therapeutics (KPTI) Return on Assets [ROA] (2013 - 2026)
Karyopharm Therapeutics' Return on Assets [ROA] was -218.08% in Q2 2026, down 111.83 percentage points from -106.25% a year earlier.
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Analysis
Karyopharm Therapeutics (KPTI) Return on Assets [ROA] (2013 - 2026) Analysis & Trends
For FY2025, Return on Assets [ROA] at Karyopharm Therapeutics came in at -143.71%, down 105.95 percentage points from FY2024.
- Return on Assets [ROA] shows a five-year change of -79.14 percentage points (FY2020 to FY2025).
- In earlier years, Return on Assets [ROA] was -37.75% in FY2024 (+10.06 pp), -47.81% in FY2023 (+2.02 pp), -49.84% in FY2022 (-9.69 pp) and -40.15% in FY2021 (+24.42 pp).
- The Q2 2026 figure marks the lowest quarterly Return on Assets [ROA] in data going back to Q4 2013.
- Compared with a year earlier, Return on Assets [ROA] was higher in three of the last seven quarters, with an average year-over-year change of -51.76 percentage points.
- The best year-over-year quarter for Return on Assets [ROA] over five years was Q3 2022 (a gain of 40.16 percentage points); the worst was Q4 2025 (a drop of 148.40 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,137.66 Bn | 1,106.24 Bn | 19.71 Bn | 20.64% |
| 2 | Johnson & Johnson | 636.13 Bn | 556.00 Bn | 17.30 Bn | 8.08% |
| 3 | AbbVie | 505.28 Bn | 478.39 Bn | 12.70 Bn | 4.65% |
| 4 | Merck | 358.10 Bn | 312.48 Bn | 12.21 Bn | 2.45% |
| 5 | Novartis Ag | 292.59 Bn | 256.58 Bn | 11.24 Bn | 10.60% |
| 6 | Astrazeneca | 265.81 Bn | 239.50 Bn | 12.86 Bn | 9.10% |
| 7 | Amgen | 237.53 Bn | 192.93 Bn | 7.24 Bn | 9.29% |
| 8 | Gilead Sciences | 194.67 Bn | 168.86 Bn | 6.22 Bn | -6.13% |
| 9 | Pfizer | 171.17 Bn | 117.82 Bn | 10.94 Bn | 2.14% |
| 10 | Karyopharm Therapeutics | 14.83 Mn | -211.60 Mn | 32.35 Mn | -218.08% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -218.08% |
| Dec 31, 2025 | -191.59% |
| Sep 30, 2025 | -123.93% |
| Jun 30, 2025 | -106.25% |
| Mar 31, 2025 | -42.80% |
| Dec 31, 2024 | -43.19% |
| Sep 30, 2024 | -43.37% |
| Jun 30, 2024 | -42.98% |
| Mar 31, 2024 | -65.78% |
| Dec 31, 2023 | -56.07% |
| Sep 30, 2023 | -49.24% |
| Jun 30, 2023 | -45.42% |
| Mar 31, 2023 | -46.22% |
| Dec 31, 2022 | -56.10% |
| Sep 30, 2022 | -36.13% |
| Jun 30, 2022 | -37.63% |
| Mar 31, 2022 | -36.07% |
| Dec 31, 2021 | -44.38% |
| Sep 30, 2021 | -76.29% |
| Jun 30, 2021 | -74.06% |
API Access
Karyopharm Therapeutics Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();