Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.65 -0.04 (-2.37%)
As of: Sep 10, 2026 · 9:31 AM EDT

Karyopharm Therapeutics (KPTI) Price to Book (2013 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Price to Book came in at 0.86 in Q2 2026, down 448.97% on a YoY basis from 0.25 in Q2 2025, and down 211.67% quarter-over-quarter from 0.27 in Q4 2025.

Analysis

Karyopharm Therapeutics (KPTI) Price to Book (2013 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has reported Price to Book for 14 consecutive years, with 0.86 the latest figure, recorded in Q2 2026.

  • For the quarter ending Q2 2026, Price to Book fell 448.97% year-over-year to 0.86; the trailing twelve-month figure through Jun 2026 stood at 0.86 (down 448.97% YoY), and the FY2025 full-year result was 0.27, up 40.1% from the prior year.
  • Price to Book retreated to 0.86 in Q2 2026 per KPTI's latest filing, from 0.27 in the prior quarter.
  • Across five years, Price to Book topped out at 0.16 in Q1 2025 and bottomed at 16.71 in Q4 2022.
  • Historically, Price to Book has averaged 2.92 across 5 years, with a median of 0.86 in 2026.
  • The sharpest annual moves came in 2023 and 2026: Price to Book soared 95.63% in 2023, then sank 448.97% in 2026.
  • Over 5 years, Price to Book stood at 16.71 in 2022, then jumped by 95.63% to 0.73 in 2023, then jumped by 37.18% to 0.46 in 2024, then surged by 40.1% to 0.27 in 2025, then sank by 211.67% to 0.86 in 2026.
  • According to Business Quant data, Price to Book over the past three periods registered 0.86, 0.27, and 0.21 for Q2 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Johnson & Johnson 663.08 Bn 642.33 Bn 17.26 Bn
2 AbbVie 453.04 Bn 446.51 Bn 12.70 Bn
3 Merck 370.87 Bn 363.78 Bn 12.21 Bn
4 Novartis Ag 305.29 Bn 298.00 Bn 11.24 Bn
5 Pfizer 162.10 Bn 150.70 Bn 10.94 Bn
6 Sanofi 53.95 Bn 46.98 Bn 10.79 Bn
7 Revolution Medicines 45.00 Bn 45.00 Bn -
8 Incyte 25.47 Bn 20.94 Bn 1.57 Bn
9 United Therapeutics 20.81 Bn 18.15 Bn 683.80 Mn
10 Karyopharm Therapeutics 51.80 Mn -13.31 Mn 32.35 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.86
Dec 31, 2025 -0.27
Sep 30, 2025 -0.21
Jun 30, 2025 -0.16
Mar 31, 2025 -0.16
Dec 31, 2024 -0.46
Sep 30, 2024 -0.65
Jun 30, 2024 -0.82
Mar 31, 2024 -1.04
Dec 31, 2023 -0.73
Sep 30, 2023 -1.53
Jun 30, 2023 -2.87
Mar 31, 2023 -9.81
Dec 31, 2022 -16.71
Sep 30, 2022 -3.15
Jun 30, 2022 -3.09
Mar 31, 2022 -7.05
Dec 31, 2021 -6.11
Sep 30, 2021 -3.49
Jun 30, 2021 -9.35