Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.61 -0.08 (-4.73%)
As of: Sep 10, 2026 · 12:50 PM EDT

Karyopharm Therapeutics (KPTI) Net Shares Issued and Repurchased (2013 - 2025)

Karyopharm Therapeutics' (KPTI) quarterly Net Shares Issued and Repurchased came in at $271787.0 in Q4 2025, down 89.83% on a YoY basis from $2.7 million in Q4 2024, and down 89.83% quarter-over-quarter from $2.7 million in Q4 2024.

Analysis

Karyopharm Therapeutics (KPTI) Net Shares Issued and Repurchased (2013 - 2025) Analysis & Trends

Karyopharm Therapeutics (KPTI) has reported Net Shares Issued and Repurchased for 11 consecutive years, with $271787.0 the latest figure, recorded in Q4 2025.

  • For the quarter ending Q4 2025, Net Shares Issued and Repurchased fell 89.83% year-over-year to $271787.0; the trailing twelve-month figure through Dec 2025 stood at $271787.0 (down 89.83% YoY), and the FY2025 full-year result was $271787.0, down 89.83% from the prior year.
  • Net Shares Issued and Repurchased slipped to $271787.0 in Q4 2025 per KPTI's latest filing, from $2.7 million in the prior quarter.
  • Across five years, Net Shares Issued and Repurchased topped out at $722.9 million in Q4 2022 and bottomed at $271787.0 in Q4 2025.
  • Historically, Net Shares Issued and Repurchased has averaged $146.6 million across 5 years, with a median of $3.6 million in 2021.
  • The sharpest annual moves came in 2022 and 2023: Net Shares Issued and Repurchased jumped 20117.2% in 2022, then plunged 99.51% in 2023.
  • Over 5 years, Net Shares Issued and Repurchased stood at $3.6 million in 2021, then surged by 20117.2% to $722.9 million in 2022, then slumped by 99.51% to $3.6 million in 2023, then fell by 25.34% to $2.7 million in 2024, then slumped by 89.83% to $271787.0 in 2025.
  • According to Business Quant data, Net Shares Issued and Repurchased over the past three periods registered $271787.0, $2.7 million, and $3.6 million for Q4 2025, Q4 2024, and Q4 2023 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Shares Issued and Repurchased (Qtr)
1 Johnson & Johnson 641.48 Bn 620.72 Bn 17.26 Bn -
2 AbbVie 446.50 Bn 439.93 Bn 12.70 Bn -
3 Merck 357.72 Bn 350.58 Bn 12.21 Bn -
4 Novartis Ag 267.52 Bn 259.83 Bn 11.24 Bn -3.07 Bn
5 Pfizer 156.69 Bn 145.00 Bn 10.94 Bn -
6 Sanofi 52.17 Bn 44.78 Bn 10.79 Bn -
7 Revolution Medicines 43.04 Bn 43.04 Bn - -
8 Incyte 24.60 Bn 20.07 Bn 1.57 Bn -
9 United Therapeutics 21.27 Bn 18.61 Bn 683.80 Mn -
10 Karyopharm Therapeutics 47.02 Mn -18.08 Mn 32.35 Mn -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 271,787.00
Dec 31, 2024 2.67 Mn
Dec 31, 2023 3.58 Mn
Dec 31, 2022 722.90 Mn
Dec 31, 2021 3.58 Mn
Mar 31, 2018 2.18 Mn
Dec 31, 2017 2.61 Mn
Mar 31, 2017 1.50 Mn
Dec 31, 2016 57,375.00
Mar 31, 2016 1.09 Mn
Dec 31, 2015 3,000.00
Mar 31, 2015 1.10 Mn
Dec 31, 2014 900,200.00
Mar 31, 2014 104,000.00
Dec 31, 2013 1.91 Mn