International Stem Cell (ISCO) Net Margin (2010 - 2026)
International Stem Cell's (ISCO) quarterly Net Margin came in at 2.65% in Q2 2026, down 539.0% year-over-year from 0.6% in Q2 2025, and up 83.56% quarter-over-quarter from 16.15% in Q4 2025.
Analysis
International Stem Cell (ISCO) Net Margin (2010 - 2026) Analysis & Trends
International Stem Cell (ISCO) has reported Net Margin for 17 consecutive years, with 2.65% the latest figure, recorded in Q2 2026.
- On a quarterly basis, Net Margin fell 539.0% year-over-year to 2.65% in Q2 2026; TTM through Jun 2026 was 3.35%, a 7.0% decrease from a year earlier, with the FY2025 full-year figure at 4.59%, down 225.0% from the prior year.
- Net Margin was 2.65% for Q2 2026 at International Stem Cell, up from 16.15% in the prior quarter.
- Over five years, Net Margin peaked at 14.07% in Q2 2023 and troughed at 24.25% in Q4 2023.
- A 5-year average of 4.56% and a median of 1.63% in 2023 frame the typical range for Net Margin.
- Across the five-year window, Net Margin jumped 3568 bps in 2022 and slumped 2540 bps in 2023, its largest moves.
- Over 5 years, Net Margin stood at 1.15% in 2022, then sank by 2204 bps to 24.25% in 2023, then surged by 102 bps to 0.49% in 2024, then plunged by 3392 bps to 16.15% in 2025, then soared by 84 bps to 2.65% in 2026.
- The last three Net Margin figures came in at 2.65% (Q2 2026), 16.15% (Q4 2025), and 1.22% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Krystal Biotech | 10.27 Bn | 9.43 Bn | 112.79 Mn | 45.94% |
| 2 | CRISPR Therapeutics AG | 5.17 Bn | 5.17 Bn | - | -895.73% |
| 3 | Iovance Biotherapeutics | 3.79 Bn | 3.49 Bn | 55.72 Mn | -47.62% |
| 4 | Legend Biotech | 3.68 Bn | 2.71 Bn | 251.50 Mn | 20.08% |
| 5 | uniQure | 3.05 Bn | 3.05 Bn | 5.49 Mn | -1,387.76% |
| 6 | Beam Therapeutics | 2.65 Bn | 2.65 Bn | - | -25,036.33% |
| 7 | Precigen | 2.44 Bn | 2.44 Bn | 52.17 Mn | 36.51% |
| 8 | Sarepta Therapeutics | 2.33 Bn | 1.53 Bn | 251.87 Mn | -1.22% |
| 9 | Vericel | 1.99 Bn | 1.83 Bn | 56.40 Mn | 2.88% |
| 10 | International Stem Cell | 2.84 Mn | 1.75 Mn | 1.46 Mn | -2.65% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -2.65% |
| Dec 31, 2025 | -16.15% |
| Sep 30, 2025 | 1.22% |
| Jun 30, 2025 | 2.74% |
| Mar 31, 2025 | -12.02% |
| Dec 31, 2024 | 0.49% |
| Sep 30, 2024 | -5.74% |
| Jun 30, 2024 | 2.66% |
| Mar 31, 2024 | -10.05% |
| Dec 31, 2023 | -24.25% |
| Sep 30, 2023 | -6.64% |
| Jun 30, 2023 | 14.07% |
| Mar 31, 2023 | -1.63% |
| Dec 31, 2022 | 1.15% |
| Sep 30, 2022 | -20.14% |
| Jun 30, 2022 | -0.10% |
| Mar 31, 2022 | -0.45% |
| Dec 31, 2021 | -19.75% |
| Sep 30, 2021 | -34.80% |
| Jun 30, 2021 | -24.28% |