International Stem Cell (ISCO) FCF Margin (2010 - 2025)
International Stem Cell (ISCO) posted FCF Margin of 1.35% for Q4 2025, up 4.41 percentage points from -3.07% a year earlier but down 0.60 percentage points from the prior quarter.
Powered by 
Analysis
International Stem Cell (ISCO) FCF Margin (2010 - 2025) Analysis & Trends
For FY2025, International Stem Cell's FCF Margin came in at -0.38%, up 1.30 percentage points from FY2024.
- Annual FCF Margin shows a five-year change of +4.79 percentage points (FY2020 to FY2025).
- In prior years, International Stem Cell's FCF Margin was -1.68% in FY2024 (-12.58 pp), 10.90% in FY2023 (+6.85 pp), 4.05% in FY2022 (+22.44 pp) and -18.39% in FY2021 (-13.22 pp).
- Quarterly FCF Margin has run from a low of -23.76% in Q1 2021 to a high of 23.85% in Q2 2023 over five years.
- On a year-over-year basis, FCF Margin increased in three of the last eight quarters, with an average year-over-year change of -5.54 percentage points.
- The strongest year-over-year quarter for FCF Margin in the past five years was Q2 2022, with a gain of 29.28 percentage points; the weakest was Q1 2021, with a drop of 34.87 percentage points.
- According to Business Quant data, FCF Margin for the three prior quarters was 1.94% (Q3 2025), -13.57% (Q2 2025) and 10.43% (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 33.76% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 28.82% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 18.33% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | 26.96% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 38.60% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 6.55% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 34.70% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | 44.00% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 2.01% |
| 10 | International Stem Cell | 1.36 Mn | -2.61 Mn | 1.46 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 1.35% |
| Sep 30, 2025 | 1.94% |
| Jun 30, 2025 | -13.57% |
| Mar 31, 2025 | 10.43% |
| Dec 31, 2024 | -3.07% |
| Sep 30, 2024 | 10.10% |
| Jun 30, 2024 | -4.16% |
| Mar 31, 2024 | -9.44% |
| Dec 31, 2023 | 8.52% |
| Sep 30, 2023 | 2.43% |
| Jun 30, 2023 | 23.85% |
| Mar 31, 2023 | 9.64% |
| Dec 31, 2022 | 3.25% |
| Sep 30, 2022 | 4.93% |
| Jun 30, 2022 | 9.47% |
| Mar 31, 2022 | -1.14% |
| Dec 31, 2021 | -17.69% |
| Sep 30, 2021 | -12.16% |
| Jun 30, 2021 | -19.80% |
| Mar 31, 2021 | -23.76% |
API Access
International Stem Cell FCF Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=fcf-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "fcf-margin", "ticker": "ISCO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=fcf-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();