International Stem Cell (ISCO) EBIT Margin (2010 - 2026)
International Stem Cell (ISCO) posted EBIT Margin of -1.31% for Q2 2026, down 8.13 percentage points from 6.82% a year earlier.
International Stem Cell (ISCO) EBIT Margin (2010 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBIT Margin at International Stem Cell was -0.90%, up 0.04 percentage points year-over-year; for FY2025, it came in at -2.93%, down 2.19 percentage points from FY2024.
- Annual EBIT Margin shows a five-year change of +36.60 percentage points (FY2020 to FY2025).
- In prior years, International Stem Cell's EBIT Margin was -0.75% in FY2024 (+7.76 pp), -8.51% in FY2023 (-6.27 pp), -2.24% in FY2022 (+24.53 pp) and -26.77% in FY2021 (+12.76 pp).
- Quarterly EBIT Margin has run from a low of -33.82% in Q3 2021 to a high of 6.82% in Q2 2025 over five years.
- On a year-over-year basis, EBIT Margin increased in four of the last seven quarters, with an average year-over-year change of +1.05 percentage points.
- The strongest year-over-year quarter for EBIT Margin in the past five years was Q1 2022, with a gain of 35.44 percentage points; the weakest was Q4 2023, with a drop of 24.96 percentage points.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | International Stem Cell | 2.80 Mn | -1.17 Mn | 1.46 Mn | -1.31% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1.31% |
| Dec 31, 2025 | -14.52% |
| Sep 30, 2025 | 3.97% |
| Jun 30, 2025 | 6.82% |
| Mar 31, 2025 | -10.10% |
| Dec 31, 2024 | 2.09% |
| Sep 30, 2024 | -4.13% |
| Jun 30, 2024 | 6.39% |
| Mar 31, 2024 | -8.36% |
| Dec 31, 2023 | -22.45% |
| Sep 30, 2023 | -4.92% |
| Jun 30, 2023 | -7.82% |
| Mar 31, 2023 | 0.10% |
| Dec 31, 2022 | 2.51% |
| Sep 30, 2022 | -17.62% |
| Jun 30, 2022 | 1.53% |
| Mar 31, 2022 | 1.24% |
| Dec 31, 2021 | -17.53% |
| Sep 30, 2021 | -33.82% |
| Jun 30, 2021 | -22.15% |
International Stem Cell EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "ISCO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();