International Stem Cell (ISCO) EBIT Margin (2010 - 2026)
International Stem Cell's (ISCO) quarterly EBIT Margin came in at 1.31% in Q2 2026, down 813.0% year-over-year from 0.18% in Q2 2025, and up 90.99% quarter-over-quarter from 14.52% in Q4 2025.
Analysis
International Stem Cell (ISCO) EBIT Margin (2010 - 2026) Analysis & Trends
International Stem Cell (ISCO) has reported EBIT Margin for 17 consecutive years, with 1.31% the latest figure, recorded in Q2 2026.
- On a quarterly basis, EBIT Margin fell 813.0% year-over-year to 1.31% in Q2 2026; TTM through Jun 2026 was 0.9%, a 4.0% increase from a year earlier, with the FY2025 full-year figure at 2.93%, down 219.0% from the prior year.
- EBIT Margin was 1.31% for Q2 2026 at International Stem Cell, up from 14.52% in the prior quarter.
- Over five years, EBIT Margin peaked at 6.82% in Q2 2025 and troughed at 22.45% in Q4 2023.
- A 5-year average of 3.92% and a median of 1.31% in 2026 frame the typical range for EBIT Margin.
- Across the five-year window, EBIT Margin soared 3544 bps in 2022 and plunged 2496 bps in 2023, its largest moves.
- Over 5 years, EBIT Margin stood at 2.51% in 2022, then slumped by 994 bps to 22.45% in 2023, then surged by 109 bps to 2.09% in 2024, then slumped by 797 bps to 14.52% in 2025, then jumped by 91 bps to 1.31% in 2026.
- The last three EBIT Margin figures came in at 1.31% (Q2 2026), 14.52% (Q4 2025), and 3.97% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Krystal Biotech | 10.27 Bn | 9.43 Bn | 112.79 Mn | 49.00% |
| 2 | CRISPR Therapeutics AG | 5.17 Bn | 5.17 Bn | - | -1,151.84% |
| 3 | Iovance Biotherapeutics | 3.79 Bn | 3.49 Bn | 55.72 Mn | -52.26% |
| 4 | Legend Biotech | 3.68 Bn | 2.71 Bn | 251.50 Mn | 14.89% |
| 5 | uniQure | 3.05 Bn | 3.05 Bn | 5.49 Mn | -893.73% |
| 6 | Beam Therapeutics | 2.65 Bn | 2.65 Bn | - | -25,827.14% |
| 7 | Precigen | 2.44 Bn | 2.44 Bn | 52.17 Mn | 41.18% |
| 8 | Sarepta Therapeutics | 2.33 Bn | 1.53 Bn | 251.87 Mn | 3.31% |
| 9 | Vericel | 1.99 Bn | 1.83 Bn | 56.40 Mn | 0.56% |
| 10 | International Stem Cell | 2.84 Mn | 1.75 Mn | 1.46 Mn | -1.31% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1.31% |
| Dec 31, 2025 | -14.52% |
| Sep 30, 2025 | 3.97% |
| Jun 30, 2025 | 6.82% |
| Mar 31, 2025 | -10.10% |
| Dec 31, 2024 | 2.09% |
| Sep 30, 2024 | -4.13% |
| Jun 30, 2024 | 6.39% |
| Mar 31, 2024 | -8.36% |
| Dec 31, 2023 | -22.45% |
| Sep 30, 2023 | -4.92% |
| Jun 30, 2023 | -7.82% |
| Mar 31, 2023 | 0.10% |
| Dec 31, 2022 | 2.51% |
| Sep 30, 2022 | -17.62% |
| Jun 30, 2022 | 1.53% |
| Mar 31, 2022 | 1.24% |
| Dec 31, 2021 | -17.53% |
| Sep 30, 2021 | -33.82% |
| Jun 30, 2021 | -22.15% |