Ironwood Pharmaceuticals (IRWD) Operating Margin (2010 - 2026)

Ironwood Pharmaceuticals' (IRWD) quarterly Operating Margin came in at 68.14% in Q1 2026, up 13889.0% year-on-year from N/an in Q1 2025, and up 142.22% quarter-over-quarter from 161.38% in Q4 2025.

Ironwood Pharmaceuticals (IRWD) Operating Margin (2010 - 2026) Analysis & Trends

Ironwood Pharmaceuticals has disclosed Operating Margin across 17 years of filings, most recently posting 68.14% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 68.14%, up 13889.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 32.19% (up 1551.0% YoY), and the FY2025 annual result was 4.97%, down 2153.0% from the prior year.
  • Operating Margin came in at 68.14% for Q1 2026 at Ironwood Pharmaceuticals, up from 161.38% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 68.14% in Q1 2026 to a low of 1008.68% in Q2 2023.
  • The 5-year median for Operating Margin is 34.78% (2024), against an average of 45.27%.
  • Across the five-year window, Operating Margin plunged 106592 bps in 2023 and jumped 103514 bps in 2024, its largest moves.
  • Ironwood Pharmaceuticals' Operating Margin stood at 120.3% in 2022, then jumped by 127 bps to 31.98% in 2023, then gained by 9 bps to 34.78% in 2024, then tumbled by 564 bps to 161.38% in 2025, then surged by 142 bps to 68.14% in 2026.
  • The last three Operating Margin figures came in at 68.14% (Q1 2026), 161.38% (Q4 2025), and 61.84% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn 16.37%
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn 36.83%
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn 41.69%
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn 20.77%
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn 23.74%
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn 22.39%
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn -122.23%
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -12.88%
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn 21.55%
10 Ironwood Pharmaceuticals 526.31 Mn 305.84 Mn - 68.14%

Historic Data

Download Data
DateValue
Mar 31, 2026 68.14%
Dec 31, 2025 -161.38%
Sep 30, 2025 61.84%
Jun 30, 2025 53.17%
Mar 31, 2025 -70.75%
Dec 31, 2024 34.78%
Sep 30, 2024 27.99%
Jun 30, 2024 26.46%
Mar 31, 2024 14.72%
Dec 31, 2023 31.98%
Sep 30, 2023 35.19%
Jun 30, 2023 -1,008.68%
Mar 31, 2023 57.75%
Dec 31, 2022 -120.30%
Sep 30, 2022 63.03%
Jun 30, 2022 57.24%
Mar 31, 2022 59.31%
Dec 31, 2021 -114.00%
Sep 30, 2021 62.82%
Jun 30, 2021 62.58%