Growth Metrics

Ironwood Pharmaceuticals (IRWD) Operating Margin (2016 - 2026)

Ironwood Pharmaceuticals' Operating Margin history spans 16 years, with the latest figure at 161.38% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 19616.0% to 161.38% in Q4 2025 year-over-year; TTM through Dec 2025 was 4.97%, a 2153.0% decrease, with the full-year FY2025 number at 4.97%, down 2153.0% from a year prior.
  • Operating Margin hit 161.38% in Q4 2025 for Ironwood Pharmaceuticals, down from 61.84% in the prior quarter.
  • Over the last five years, Operating Margin for IRWD hit a ceiling of 666.87% in Q4 2023 and a floor of 1008.68% in Q2 2023.
  • Historically, Operating Margin has averaged 2.19% across 5 years, with a median of 52.13% in 2021.
  • Biggest five-year swings in Operating Margin: crashed -106592bps in 2023 and later soared 103514bps in 2024.
  • Tracing IRWD's Operating Margin over 5 years: stood at 114.0% in 2021, then surged by 156bps to 63.77% in 2022, then surged by 946bps to 666.87% in 2023, then plummeted by -95bps to 34.78% in 2024, then tumbled by -564bps to 161.38% in 2025.
  • Business Quant data shows Operating Margin for IRWD at 161.38% in Q4 2025, 61.84% in Q3 2025, and 53.17% in Q2 2025.