Ironwood Pharmaceuticals Inc (IRWD) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

177,764,000Shares Outstanding

155,594,959Shares held by institutions

$633,271,483Value of institutional holdings

87.53%Institutional ownership %

1.26%Shares Changed QoQ

194No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Ironwood Pharmaceuticals Inc (NASDAQ:IRWD) is held by 194 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 86.8% of outstanding shares in December 2025, down from 90.5% in September 2025.
They increased total shares held in Ironwood Pharmaceuticals by 0.88% from last quarter, and the number of investors in IRWD decreased 12.61% annually.
Of these 194 holders, 113 added to their stakes in Ironwood Pharmaceuticals, 51 trimmed positions, and 30 made no changes.
Institutional investors collectively held 154.3Mn shares in Ironwood Pharmaceuticals as of December 2025, up by 1.34Mn shares quarter on quarter, and down 16.21Mn shares year over year.
ARMISTICE CAPITAL, LLC holds the largest position in IRWD at 16.02Mn shares as of December 31, 2025, or 9.01% of shares outstanding.
The most significant purchases of IRWD for the quarter ending December 2025 came from Goldman Sachs Group Inc (1.47Mn), MARSHALL WACE, LLP (1.28Mn), State Street Corp (1.25Mn), Federated Hermes, Inc. (1.16Mn), Hillsdale Investment Management Inc. (1.16Mn).
Leading sellers of Ironwood Pharmaceuticals shares for the quarter ending December 2025 were Bank Of America Corp /De/ (11.87Mn), Qube Research & Technologies Ltd (1.13Mn), AQR CAPITAL MANAGEMENT LLC (655.0K), Barclays Plc (618.05K), LOS ANGELES CAPITAL MANAGEMENT LLC (495.72K).
According to Business Quant data, leading holders of IRWD for December 2025 are ARMISTICE CAPITAL, LLC (16.02Mn), VANGUARD GROUP INC (15.96Mn), Sarissa Capital Management LP (15.92Mn), BlackRock, Inc. (12.78Mn), Bank Of America Corp /De/ (11.52Mn), RENAISSANCE TECHNOLOGIES LLC (8.2Mn), ACADIAN ASSET MANAGEMENT LLC (6.46Mn), CHARLES SCHWAB INVESTMENT MANAGEMENT INC (4.98Mn), AQR CAPITAL MANAGEMENT LLC (4.72Mn), MARSHALL WACE, LLP (4.42Mn).

194 Institutional Holders

155,594,959 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ARMISTICE CAPITAL, LLC	31 Dec, 2025	16,025,000	-125,000	-0.77%	$54,004,250.00
VANGUARD GROUP INC	31 Dec, 2025	15,958,196	-113,810	-0.71%	$53,779,120.00
Sarissa Capital Management LP	31 Dec, 2025	15,919,435	0	0.00%	$53,648,496.00
BlackRock, Inc.	31 Dec, 2025	12,784,806	722,248	5.99%	$43,084,796.00
Bank Of America Corp /De/	31 Dec, 2025	11,521,660	-11,869,428	-50.74%	$38,827,995.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	8,204,973	-147,200	-1.76%	$27,650,759.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	6,457,817	-44,676	-0.69%	$21,746.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	4,975,939	58,603	1.19%	$16,768,914.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	4,723,531	-655,004	-12.18%	$15,918,299.00
MARSHALL WACE, LLP	31 Dec, 2025	4,424,002	1,279,863	40.71%	$14,908,888.00
State Street Corp	31 Dec, 2025	4,411,222	1,254,915	39.76%	$14,865,818.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,623,534	8,547	0.24%	$12,213,817.00
Federated Hermes, Inc.	31 Dec, 2025	3,318,137	1,161,033	53.82%	$11,182,122.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	3,140,100	-176,400	-5.32%	$10,582,137.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	2,853,205	318,694	12.57%	$9,615,301.00
JANE STREET GROUP, LLC	31 Dec, 2025	2,819,562	498,467	21.48%	$9,501,924.00
JACOBS LEVY EQUITY MANAGEMENT, INC	31 Dec, 2025	2,759,667	839,137	43.69%	$9,300,078.00
Goldman Sachs Group Inc	31 Dec, 2025	2,550,630	1,466,263	135.22%	$8,595,624.00
Connor, Clark & Lunn Investment Management Ltd.	31 Dec, 2025	1,990,927	-170,891	-7.90%	$6,709,424.00
Qube Research & Technologies Ltd	31 Dec, 2025	1,681,229	-1,125,681	-40.10%	$5,665,742.00

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