Iovance Biotherapeutics (IOVA) Net Margin (2023 - 2026)

Iovance Biotherapeutics (IOVA) posted quarterly Net Margin of 110.61% for Q1 2026, up 12490.0% year-over-year from N/an in Q1 2025, and down 1226.38% quarter-over-quarter from 9.82% in Q4 2025.

Iovance Biotherapeutics (IOVA) Net Margin (2023 - 2026) Analysis & Trends

Iovance Biotherapeutics (IOVA) has reported Net Margin for 4 consecutive years, with 110.61% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Margin rose 12490.0% year-over-year to 110.61%; the TTM figure through Mar 2026 stood at 95.73% (up 8077.0% YoY), while the FY2025 annual figure was 117.84%, up 10902.0% from the prior year.
  • Net Margin eased to 110.61% in Q1 2026 per IOVA's latest filing, from 9.82% in the prior quarter.
  • Across five years, Net Margin topped out at 9.82% in Q4 2025 and bottomed at 44759.66% in Q2 2023.
  • Historically, Net Margin has averaged 9181.01% across 4 years, with a median of 210.89% in 2025.
  • Annual changes were most pronounced in 2024 — Net Margin jumped 4444764 bps — and 2025, when it surged 743 bps.
  • Iovance Biotherapeutics' Net Margin stood at 24136.51% in 2023, then jumped by 100 bps to 106.66% in 2024, then jumped by 109 bps to 9.82% in 2025, then slumped by 1226 bps to 110.61% in 2026.
  • Business Quant data shows IOVA's Net Margin at 110.61% in Q1 2026, 9.82% in Q4 2025, and 135.28% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Iovance Biotherapeutics 3.16 Bn 2.86 Bn 55.72 Mn -47.62%

Historic Data

Download Data
DateValue
Jun 30, 2026 -47.62%
Mar 31, 2026 -110.61%
Dec 31, 2025 9.82%
Sep 30, 2025 -135.28%
Jun 30, 2025 -186.27%
Mar 31, 2025 -235.51%
Dec 31, 2024 -106.66%
Sep 30, 2024 -142.71%
Jun 30, 2024 -312.03%
Mar 31, 2024 -15,800.84%
Dec 31, 2023 -24,136.51%
Sep 30, 2023 -24,255.86%
Jun 30, 2023 -44,759.66%