Ionis Pharmaceuticals (IONS) Research & Development (2009 - 2026)
Ionis Pharmaceuticals' (IONS) quarterly Research & Development came in at $210.2 million in Q1 2026, up 4.69% year-on-year from $200.8 million in Q1 2025, and down 24.84% quarter-over-quarter from $279.6 million in Q4 2025.
Ionis Pharmaceuticals (IONS) Research & Development (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Research & Development history runs 18 years deep, the most recent figure standing at $210.2 million for Q1 2026.
- On a quarterly basis, Research & Development rose 4.69% year-over-year to $210.2 million in Q1 2026; TTM through Mar 2026 was $925.0 million, a 4.16% increase from a year earlier, with the FY2025 full-year figure at $915.6 million, up 1.56% from the prior year.
- Research & Development fell to $210.2 million in Q1 2026 per IONS's latest filing, from $279.6 million in the prior quarter.
- Across five years, Research & Development topped out at $279.6 million in Q4 2025 and bottomed at -$444.9 million in Q4 2022.
- The 5-year median for Research & Development is $215.3 million (2023), against an average of $176.9 million.
- Across the five-year window, Research & Development soared 157.67% in 2023 and slipped 6.28% in 2025, its largest moves.
- Year by year, Research & Development stood at -$444.9 million in 2022, then surged by 157.67% to $256.6 million in 2023, then dropped by 4.31% to $245.5 million in 2024, then rose by 13.91% to $279.6 million in 2025, then fell by 24.84% to $210.2 million in 2026.
- Per Business Quant, the three latest IONS Research & Development figures stand at $210.2 million (Q1 2026), $279.6 million (Q4 2025), and $217.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -17.94 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 1.46 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 541.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 961.60 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 1.54 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 15.66 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -443.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 343.97 Mn |
| 10 | Ionis Pharmaceuticals | 9.35 Bn | 7.43 Bn | 243.11 Mn | 210.17 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 210.17 Mn |
| Dec 31, 2025 | 279.65 Mn |
| Sep 30, 2025 | 217.75 Mn |
| Jun 30, 2025 | 217.46 Mn |
| Mar 31, 2025 | 200.76 Mn |
| Dec 31, 2024 | 245.49 Mn |
| Sep 30, 2024 | 219.76 Mn |
| Jun 30, 2024 | 222.06 Mn |
| Mar 31, 2024 | 214.22 Mn |
| Dec 31, 2023 | 256.56 Mn |
| Sep 30, 2023 | 215.33 Mn |
| Jun 30, 2023 | 229.93 Mn |
| Mar 31, 2023 | 197.81 Mn |
| Dec 31, 2022 | -444.88 Mn |
| Sep 30, 2022 | 182.99 Mn |
| Jun 30, 2022 | 180.76 Mn |
| Mar 31, 2022 | 161.13 Mn |
| Dec 31, 2021 | -429.08 Mn |
| Sep 30, 2021 | 184.77 Mn |
| Jun 30, 2021 | 139.31 Mn |