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Ionis Pharmaceuticals (IONS) Research & Development (2016 - 2025)

Ionis Pharmaceuticals has reported Research & Development over the past 17 years, most recently at $279.6 million for Q4 2025.

  • Quarterly results put Research & Development at $279.6 million for Q4 2025, up 13.91% from a year ago — trailing twelve months through Dec 2025 was $915.6 million (up 1.56% YoY), and the annual figure for FY2025 was $915.6 million, up 1.56%.
  • Research & Development for Q4 2025 was $279.6 million at Ionis Pharmaceuticals, up from $217.8 million in the prior quarter.
  • Over the last five years, Research & Development for IONS hit a ceiling of $279.6 million in Q4 2025 and a floor of -$444.9 million in Q4 2022.
  • Median Research & Development over the past 5 years was $207.5 million (2024), compared with a mean of $141.6 million.
  • Biggest five-year swings in Research & Development: tumbled 351.25% in 2021 and later soared 157.67% in 2023.
  • Ionis Pharmaceuticals' Research & Development stood at -$429.1 million in 2021, then fell by 3.68% to -$444.9 million in 2022, then soared by 157.67% to $256.6 million in 2023, then decreased by 4.31% to $245.5 million in 2024, then grew by 13.91% to $279.6 million in 2025.
  • The last three reported values for Research & Development were $279.6 million (Q4 2025), $217.8 million (Q3 2025), and $217.5 million (Q2 2025) per Business Quant data.