Ionis Pharmaceuticals (IONS) Research & Development (2009 - 2026)

Ionis Pharmaceuticals' Research & Development history runs 18 years deep, the most recent figure standing at $210.2 million for Q1 2026.

• In Q1 2026, Research & Development rose 4.69% year-over-year to $210.2 million; the TTM figure through Mar 2026 stood at $925.0 million (up 4.16% YoY), while the FY2025 annual figure was $915.6 million, up 1.56% from the prior year.
• Research & Development was $210.2 million for Q1 2026 at Ionis Pharmaceuticals, down from $279.6 million in the prior quarter.
• In the past five years, Research & Development ranged from a high of $279.6 million in Q4 2025 to a low of -$444.9 million in Q4 2022.
• Historically, Research & Development has averaged $176.9 million across 5 years, with a median of $215.3 million in 2023.
• The sharpest annual moves came in 2023 and 2025: Research & Development jumped 157.67% in 2023, then retreated 6.28% in 2025.
• A 5-year view of Research & Development shows it stood at -$444.9 million in 2022, then surged by 157.67% to $256.6 million in 2023, then dropped by 4.31% to $245.5 million in 2024, then rose by 13.91% to $279.6 million in 2025, then fell by 24.84% to $210.2 million in 2026.
• The last three Research & Development figures came in at $210.2 million (Q1 2026), $279.6 million (Q4 2025), and $217.8 million (Q3 2025), per Business Quant data.