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Ionis Pharmaceuticals (IONS) Net Cash Flow (2016 - 2025)

Ionis Pharmaceuticals has reported Net Cash Flow over the past 17 years, most recently at $34.0 million for Q4 2025.

  • Quarterly results put Net Cash Flow at $34.0 million for Q4 2025, up 136.9% from a year ago — trailing twelve months through Dec 2025 was $129.5 million (up 182.52% YoY), and the annual figure for FY2025 was $129.5 million, up 182.52%.
  • Net Cash Flow for Q4 2025 was $34.0 million at Ionis Pharmaceuticals, down from $41.1 million in the prior quarter.
  • Over the last five years, Net Cash Flow for IONS hit a ceiling of $236.3 million in Q4 2021 and a floor of -$326.5 million in Q1 2022.
  • Median Net Cash Flow over the past 5 years was $27.2 million (2023), compared with a mean of -$1.3 million.
  • Biggest five-year swings in Net Cash Flow: crashed 2065.0% in 2022 and later skyrocketed 673.14% in 2023.
  • Ionis Pharmaceuticals' Net Cash Flow stood at $236.3 million in 2021, then tumbled by 116.53% to -$39.1 million in 2022, then surged by 219.99% to $46.9 million in 2023, then tumbled by 296.35% to -$92.0 million in 2024, then soared by 136.9% to $34.0 million in 2025.
  • The last three reported values for Net Cash Flow were $34.0 million (Q4 2025), $41.1 million (Q3 2025), and $32.5 million (Q2 2025) per Business Quant data.