Ionis Pharmaceuticals (IONS) Net Cash Flow (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly Net Cash Flow of -$198.7 million in Q1 2026, down 685.19% quarter-over-quarter from $34.0 million in Q4 2025, and down 1008.2% on a YoY basis from $21.9 million in Q1 2025.
Ionis Pharmaceuticals (IONS) Net Cash Flow (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Net Cash Flow history runs 18 years deep, the most recent figure standing at -$198.7 million for Q1 2026.
- In Q1 2026, Net Cash Flow fell 1008.2% year-over-year to -$198.7 million; the TTM figure through Mar 2026 stood at -$91.1 million (down 7.52% YoY), while the FY2025 annual figure was $129.5 million, up 182.52% from the prior year.
- Net Cash Flow was -$198.7 million for Q1 2026 at Ionis Pharmaceuticals, down from $34.0 million in the prior quarter.
- In the past five years, Net Cash Flow ranged from a high of $115.7 million in Q2 2023 to a low of -$326.5 million in Q1 2022.
- Historically, Net Cash Flow has averaged -$40.9 million across 5 years, with a median of -$20.2 million in 2022.
- The sharpest annual moves came in 2022 and 2023: Net Cash Flow sank 2065.0% in 2022, then surged 673.14% in 2023.
- A 5-year view of Net Cash Flow shows it stood at -$39.1 million in 2022, then jumped by 219.99% to $46.9 million in 2023, then sank by 296.35% to -$92.0 million in 2024, then surged by 136.9% to $34.0 million in 2025, then plunged by 685.19% to -$198.7 million in 2026.
- The last three Net Cash Flow figures came in at -$198.7 million (Q1 2026), $34.0 million (Q4 2025), and $41.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 625.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 457.40 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 664,983.53 |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -198.74 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -198.74 Mn |
| Mar 31, 2026 | -198.74 Mn |
| Dec 31, 2025 | 33.96 Mn |
| Dec 31, 2025 | 33.96 Mn |
| Sep 30, 2025 | 41.12 Mn |
| Sep 30, 2025 | 41.12 Mn |
| Jun 30, 2025 | 32.52 Mn |
| Jun 30, 2025 | 32.52 Mn |
| Mar 31, 2025 | 21.88 Mn |
| Mar 31, 2025 | 21.88 Mn |
| Dec 31, 2024 | -92.04 Mn |
| Dec 31, 2024 | -92.04 Mn |
| Sep 30, 2024 | 40.26 Mn |
| Sep 30, 2024 | 40.26 Mn |
| Jun 30, 2024 | -54.87 Mn |
| Jun 30, 2024 | -54.87 Mn |
| Mar 31, 2024 | -50.26 Mn |
| Mar 31, 2024 | -50.26 Mn |
| Dec 31, 2023 | 46.88 Mn |
| Dec 31, 2023 | 46.88 Mn |