Ionis Pharmaceuticals (IONS) Free Cash Flow (2009 - 2026)

Ionis Pharmaceuticals' Free Cash Flow history runs 18 years deep, the most recent figure standing at -$814.6 million for Q1 2026.

• In Q1 2026, Free Cash Flow fell 398.67% year-over-year to -$814.6 million; the TTM figure through Mar 2026 stood at -$971.3 million (down 74.95% YoY), while the FY2025 annual figure was -$320.0 million, up 41.41% from the prior year.
• Free Cash Flow was -$814.6 million for Q1 2026 at Ionis Pharmaceuticals, down from -$159.0 million in the prior quarter.
• In the past five years, Free Cash Flow ranged from a high of $139.0 million in Q2 2025 to a low of -$814.6 million in Q1 2026.
• Historically, Free Cash Flow has averaged -$134.0 million across 5 years, with a median of -$126.1 million in 2024.
• The sharpest annual moves came in 2023 and 2025: Free Cash Flow plunged 410.36% in 2023, then soared 210.24% in 2025.
• A 5-year view of Free Cash Flow shows it stood at -$204.3 million in 2022, then soared by 128.05% to $57.3 million in 2023, then sank by 347.11% to -$141.6 million in 2024, then declined by 12.26% to -$159.0 million in 2025, then tumbled by 412.31% to -$814.6 million in 2026.
• The last three Free Cash Flow figures came in at -$814.6 million (Q1 2026), -$159.0 million (Q4 2025), and -$136.7 million (Q3 2025), per Business Quant data.