Ionis Pharmaceuticals (IONS) Cost of Revenue (2018 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Cost of Revenue of $3.0 million in Q1 2026, down 62.51% quarter-over-quarter from $8.0 million in Q4 2025, and up 103.9% on a YoY basis from $1.5 million in Q1 2025.

Ionis Pharmaceuticals (IONS) Cost of Revenue (2018 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Cost of Revenue history runs 9 years deep, the most recent figure standing at $3.0 million for Q1 2026.

  • In Q1 2026, Cost of Revenue rose 103.9% year-over-year to $3.0 million; the TTM figure through Mar 2026 stood at $17.4 million (up 65.55% YoY), while the FY2025 annual figure was $15.9 million, up 41.85% from the prior year.
  • Cost of Revenue was $3.0 million for Q1 2026 at Ionis Pharmaceuticals, down from $8.0 million in the prior quarter.
  • In the past five years, Cost of Revenue ranged from a high of $8.0 million in Q4 2025 to a low of $1.1 million in Q3 2024.
  • Historically, Cost of Revenue has averaged $3.1 million across 5 years, with a median of $3.0 million in 2026.
  • The sharpest annual moves came in 2023 and 2025: Cost of Revenue slumped 67.79% in 2023, then surged 118.3% in 2025.
  • A 5-year view of Cost of Revenue shows it stood at $3.7 million in 2022, then declined by 16.93% to $3.1 million in 2023, then advanced by 25.08% to $3.8 million in 2024, then surged by 107.75% to $8.0 million in 2025, then plunged by 62.51% to $3.0 million in 2026.
  • The last three Cost of Revenue figures came in at $3.0 million (Q1 2026), $8.0 million (Q4 2025), and $2.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cost of Rev (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 64.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 48,670.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 392.80 Mn
9 Abivax 91.96 Bn 91.96 Bn - 2.05 Mn
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn 2.98 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 2.98 Mn
Mar 31, 2026 2.98 Mn
Dec 31, 2025 7.96 Mn
Dec 31, 2025 7.96 Mn
Sep 30, 2025 2.34 Mn
Sep 30, 2025 2.34 Mn
Jun 30, 2025 4.15 Mn
Jun 30, 2025 4.15 Mn
Mar 31, 2025 1.46 Mn
Mar 31, 2025 1.46 Mn
Dec 31, 2024 3.83 Mn
Dec 31, 2024 3.83 Mn
Sep 30, 2024 1.07 Mn
Sep 30, 2024 1.07 Mn
Jun 30, 2024 4.16 Mn
Jun 30, 2024 4.16 Mn
Mar 31, 2024 2.15 Mn
Mar 31, 2024 2.15 Mn
Dec 31, 2023 3.06 Mn
Dec 31, 2023 3.06 Mn