Vertex Pharmaceuticals (VRTX) Cost of Revenue (2016 - 2026)
Quarterly Cost of Revenue rose 8.21% to $392.8 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was $1.7 billion through Mar 2026, up 8.4% year-over-year, with the annual reading at $1.7 billion for FY2025, 7.89% up from the prior year.
Vertex Pharmaceuticals' Cost of Revenue history spans 16 years, with the latest figure at $392.8 million for Q1 2026.
- Cost of Revenue came in at $392.8 million for Q1 2026, down from $466.0 million in the prior quarter.
- In the past five years, Cost of Revenue ranged from a high of $466.0 million in Q4 2025 to a low of $245.8 million in Q1 2022.
- The 5-year median for Cost of Revenue is $363.0 million (2025), against an average of $348.1 million.
- Year-over-year, Cost of Revenue grew 29.9% in 2023 and then grew 5.65% in 2025.
- Vertex Pharmaceuticals' Cost of Revenue stood at $283.3 million in 2022, then increased by 29.9% to $368.0 million in 2023, then rose by 15.05% to $423.4 million in 2024, then rose by 10.06% to $466.0 million in 2025, then dropped by 15.71% to $392.8 million in 2026.
- Per Business Quant, the three most recent readings for VRTX's Cost of Revenue are $392.8 million (Q1 2026), $466.0 million (Q4 2025), and $414.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cost of Rev (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | - |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | 64.20 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 392.80 Mn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 296.00 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 207.52 Mn |
| 10 | Revolution Medicines | 30.42 Bn | 30.42 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 392.80 Mn |
| Mar 31, 2026 | 392.80 Mn |
| Dec 31, 2025 | 466.00 Mn |
| Dec 31, 2025 | 466.00 Mn |
| Sep 30, 2025 | 414.80 Mn |
| Sep 30, 2025 | 414.80 Mn |
| Jun 30, 2025 | 407.50 Mn |
| Jun 30, 2025 | 407.50 Mn |
| Mar 31, 2025 | 363.00 Mn |
| Mar 31, 2025 | 363.00 Mn |
| Dec 31, 2024 | 423.40 Mn |
| Dec 31, 2024 | 423.40 Mn |
| Sep 30, 2024 | 392.60 Mn |
| Sep 30, 2024 | 392.60 Mn |
| Jun 30, 2024 | 371.90 Mn |
| Jun 30, 2024 | 371.90 Mn |
| Mar 31, 2024 | 342.60 Mn |
| Mar 31, 2024 | 342.60 Mn |
| Dec 31, 2023 | 368.00 Mn |
| Dec 31, 2023 | 368.00 Mn |
| Sep 30, 2023 | 318.70 Mn |
| Sep 30, 2023 | 318.70 Mn |
| Jun 30, 2023 | 308.60 Mn |
| Jun 30, 2023 | 308.60 Mn |
| Mar 31, 2023 | 266.90 Mn |
| Mar 31, 2023 | 266.90 Mn |
| Dec 31, 2022 | 283.30 Mn |
| Dec 31, 2022 | 283.30 Mn |
| Sep 30, 2022 | 289.40 Mn |
| Sep 30, 2022 | 289.40 Mn |
| Jun 30, 2022 | 261.80 Mn |
| Jun 30, 2022 | 261.80 Mn |
| Mar 31, 2022 | 245.80 Mn |
| Mar 31, 2022 | 245.80 Mn |
| Dec 31, 2021 | 247.40 Mn |
| Dec 31, 2021 | 247.40 Mn |
| Sep 30, 2021 | 236.50 Mn |
| Sep 30, 2021 | 236.50 Mn |
| Jun 30, 2021 | 228.00 Mn |
| Jun 30, 2021 | 228.00 Mn |
| Mar 31, 2021 | 192.30 Mn |
| Mar 31, 2021 | 192.30 Mn |
| Dec 31, 2020 | 203.10 Mn |
| Dec 31, 2020 | 203.10 Mn |
| Sep 30, 2020 | 186.18 Mn |
| Sep 30, 2020 | 186.18 Mn |
| Jun 30, 2020 | 184.52 Mn |
| Jun 30, 2020 | 184.52 Mn |
| Mar 31, 2020 | 162.50 Mn |
| Mar 31, 2020 | 162.50 Mn |
| Dec 31, 2019 | 185.01 Mn |
| Dec 31, 2019 | 185.01 Mn |
| Sep 30, 2019 | 131.91 Mn |
| Sep 30, 2019 | 131.91 Mn |
| Jun 30, 2019 | 135.74 Mn |
| Jun 30, 2019 | 135.74 Mn |
| Mar 31, 2019 | 95.09 Mn |
| Mar 31, 2019 | 95.09 Mn |
| Dec 31, 2018 | 122.29 Mn |
| Dec 31, 2018 | 122.29 Mn |
| Sep 30, 2018 | 111.26 Mn |
| Sep 30, 2018 | 111.26 Mn |
| Jun 30, 2018 | 104.38 Mn |
| Jun 30, 2018 | 104.38 Mn |
| Mar 31, 2018 | 71.61 Mn |
| Mar 31, 2018 | 71.61 Mn |
| Dec 31, 2017 | 84.05 Mn |
| Dec 31, 2017 | 84.05 Mn |
| Sep 30, 2017 | 72.87 Mn |
| Sep 30, 2017 | 72.87 Mn |
| Jun 30, 2017 | 71.21 Mn |
| Jun 30, 2017 | 71.21 Mn |
| Mar 31, 2017 | 46.99 Mn |
| Mar 31, 2017 | 46.99 Mn |
| Dec 31, 2016 | 59.65 Mn |
| Dec 31, 2016 | 59.65 Mn |
| Sep 30, 2016 | 53.22 Mn |
| Sep 30, 2016 | 53.22 Mn |
| Jun 30, 2016 | 44.15 Mn |
| Jun 30, 2016 | 44.15 Mn |