Ionis Pharmaceuticals (IONS) Change in Cash (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly Change in Cash of $176.7 million for Q2 2026, up 433.6% year-over-year from $33.1 million in Q2 2025, and up 188.84% quarter-over-quarter from -$198.9 million in Q1 2026.
Ionis Pharmaceuticals (IONS) Change in Cash (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Change in Cash history runs 18 years deep, the most recent figure standing at $176.7 million for Q2 2026.
- In Q2 2026, Change in Cash rose 433.6% year-over-year to $176.7 million; the TTM figure through Jun 2026 stood at $52.8 million (up 1493.51% YoY), while the FY2025 annual figure was $130.2 million, up 182.82% from the prior year.
- Change in Cash for Q2 2026 stood at $176.7 million, up from -$198.9 million in the prior quarter.
- The five-year high for Change in Cash was $176.7 million in Q2 2026, with the low at -$326.7 million in Q1 2022.
- The 5-year median for Change in Cash is $759500.0 (2022), against an average of -$28.8 million.
- The sharpest annual moves came in 2022 and 2023: Change in Cash plunged 2080.95% in 2022, then soared 662.05% in 2023.
- Ionis Pharmaceuticals' Change in Cash stood at -$38.5 million in 2022, then soared by 222.55% to $47.2 million in 2023, then sank by 296.01% to -$92.5 million in 2024, then jumped by 136.66% to $33.9 million in 2025, then soared by 420.9% to $176.7 million in 2026.
- Business Quant data shows IONS's Change in Cash at $176.7 million in Q2 2026, -$198.9 million in Q1 2026, and $33.9 million in Q4 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 374.50 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 427.25 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -1.97 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 225.59 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -2.94 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Ionis Pharmaceuticals | 9.48 Bn | 7.43 Bn | 265.21 Mn | 176.68 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 176.68 Mn |
| Mar 31, 2026 | -198.88 Mn |
| Dec 31, 2025 | 33.92 Mn |
| Sep 30, 2025 | 41.04 Mn |
| Jun 30, 2025 | 33.11 Mn |
| Mar 31, 2025 | 22.12 Mn |
| Dec 31, 2024 | -92.53 Mn |
| Sep 30, 2024 | 40.61 Mn |
| Jun 30, 2024 | -54.90 Mn |
| Mar 31, 2024 | -50.38 Mn |
| Dec 31, 2023 | 47.21 Mn |
| Sep 30, 2023 | -72.73 Mn |
| Jun 30, 2023 | 115.76 Mn |
| Mar 31, 2023 | 32.56 Mn |
| Dec 31, 2022 | -38.52 Mn |
| Sep 30, 2022 | -206.92 Mn |
| Jun 30, 2022 | -20.60 Mn |
| Mar 31, 2022 | -326.68 Mn |
| Dec 31, 2021 | 236.24 Mn |
| Sep 30, 2021 | 67.83 Mn |