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Ionis Pharmaceuticals (IONS) Change in Cash (2016 - 2025)

Ionis Pharmaceuticals has reported Change in Cash over the past 17 years, most recently at $33.9 million for Q4 2025.

  • Quarterly results put Change in Cash at $33.9 million for Q4 2025, up 136.66% from a year ago — trailing twelve months through Dec 2025 was $130.2 million (up 182.82% YoY), and the annual figure for FY2025 was $130.2 million, up 182.82%.
  • Change in Cash for Q4 2025 was $33.9 million at Ionis Pharmaceuticals, down from $41.0 million in the prior quarter.
  • Over the last five years, Change in Cash for IONS hit a ceiling of $236.2 million in Q4 2021 and a floor of -$326.7 million in Q1 2022.
  • Median Change in Cash over the past 5 years was $27.3 million (2023), compared with a mean of -$1.3 million.
  • Biggest five-year swings in Change in Cash: plummeted 2080.95% in 2022 and later soared 662.05% in 2023.
  • Ionis Pharmaceuticals' Change in Cash stood at $236.2 million in 2021, then tumbled by 116.31% to -$38.5 million in 2022, then surged by 222.55% to $47.2 million in 2023, then crashed by 296.01% to -$92.5 million in 2024, then soared by 136.66% to $33.9 million in 2025.
  • The last three reported values for Change in Cash were $33.9 million (Q4 2025), $41.0 million (Q3 2025), and $33.1 million (Q2 2025) per Business Quant data.