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Ionis Pharmaceuticals (IONS) Cash from Operations (2016 - 2025)

Ionis Pharmaceuticals has reported Cash from Operations over the past 17 years, most recently at 137709000.0 for Q4 2025.

  • Quarterly results put Cash from Operations at 137709000.0 for Q4 2025, down 18.57% from a year ago — trailing twelve months through Dec 2025 was 268583000.0 (up 46.38% YoY), and the annual figure for FY2025 was 268583000.0, up 46.38%.
  • Cash from Operations for Q4 2025 was 137709000.0 at Ionis Pharmaceuticals, down from 131437000.0 in the prior quarter.
  • Over the last five years, Cash from Operations for IONS hit a ceiling of 203687000.0 in Q4 2021 and a floor of 200195000.0 in Q4 2022.
  • Median Cash from Operations over the past 5 years was 103193000.0 (2023), compared with a mean of 66030700.0.
  • Biggest five-year swings in Cash from Operations: plummeted 619.99% in 2021 and later skyrocketed 226.24% in 2025.
  • Ionis Pharmaceuticals' Cash from Operations stood at 203687000.0 in 2021, then crashed by 198.29% to 200195000.0 in 2022, then skyrocketed by 116.42% to 32865000.0 in 2023, then crashed by 453.38% to 116139000.0 in 2024, then decreased by 18.57% to 137709000.0 in 2025.
  • The last three reported values for Cash from Operations were 137709000.0 (Q4 2025), 131437000.0 (Q3 2025), and 151338000.0 (Q2 2025) per Business Quant data.