Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly Cash from Operations of 565531000.0 for Q2 2026, up 273.69% year-over-year from 151338000.0 in Q2 2025, and up 171.33% quarter-over-quarter from 792819000.0 in Q1 2026.
Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Cash from Operations history runs 18 years deep, the most recent figure standing at 565531000.0 for Q2 2026.
- In Q2 2026, Cash from Operations rose 273.69% year-over-year to 565531000.0; the TTM figure through Jun 2026 stood at 496434000.0 (down 115.31% YoY), while the FY2025 annual figure was 268583000.0, up 46.38% from the prior year.
- Cash from Operations for Q2 2026 stood at 565531000.0, up from 792819000.0 in the prior quarter.
- The five-year high for Cash from Operations was 565531000.0 in Q2 2026, with the low at 792819000.0 in Q1 2026.
- The 5-year median for Cash from Operations is 115564500.0 (2024), against an average of 87705611.11.
- The sharpest annual moves came in 2024 and 2026: Cash from Operations sank 453.38% in 2024, then surged 273.69% in 2026.
- Ionis Pharmaceuticals' Cash from Operations stood at 200195000.0 in 2022, then surged by 116.42% to 32865000.0 in 2023, then tumbled by 453.38% to 116139000.0 in 2024, then fell by 18.57% to 137709000.0 in 2025, then soared by 510.67% to 565531000.0 in 2026.
- Business Quant data shows IONS's Cash from Operations at 565531000.0 in Q2 2026, 792819000.0 in Q1 2026, and 137709000.0 in Q4 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.13 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 813.00 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -387.32 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 462.82 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -1.76 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 728.46 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 326.72 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -88.83 Mn |
| 10 | Ionis Pharmaceuticals | 9.48 Bn | 7.43 Bn | 265.21 Mn | 565.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 565.53 Mn |
| Jun 30, 2026 | 565.53 Mn |
| Mar 31, 2026 | -792.82 Mn |
| Mar 31, 2026 | -792.82 Mn |
| Dec 31, 2025 | -137.71 Mn |
| Dec 31, 2025 | -137.71 Mn |
| Sep 30, 2025 | -131.44 Mn |
| Sep 30, 2025 | -131.44 Mn |
| Jun 30, 2025 | 151.34 Mn |
| Jun 30, 2025 | 151.34 Mn |
| Mar 31, 2025 | -150.78 Mn |
| Mar 31, 2025 | -150.78 Mn |
| Dec 31, 2024 | -116.14 Mn |
| Dec 31, 2024 | -116.14 Mn |
| Sep 30, 2024 | -114.99 Mn |
| Sep 30, 2024 | -114.99 Mn |
| Jun 30, 2024 | -119.88 Mn |
| Jun 30, 2024 | -119.88 Mn |
| Mar 31, 2024 | -149.94 Mn |
| Mar 31, 2024 | -149.94 Mn |