Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly Cash from Operations of 792819000.0 in Q1 2026, down 475.72% quarter-over-quarter from 137709000.0 in Q4 2025, and down 425.83% on a YoY basis from 243323484.13 in Q1 2025.
Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Cash from Operations history runs 18 years deep, the most recent figure standing at 792819000.0 for Q1 2026.
- In Q1 2026, Cash from Operations fell 425.83% year-over-year to 792819000.0; the TTM figure through Mar 2026 stood at 910627000.0 (down 81.48% YoY), while the FY2025 annual figure was 268583000.0, up 46.38% from the prior year.
- Cash from Operations was 792819000.0 for Q1 2026 at Ionis Pharmaceuticals, down from 137709000.0 in the prior quarter.
- In the past five years, Cash from Operations ranged from a high of 151338000.0 in Q2 2025 to a low of 792819000.0 in Q1 2026.
- Historically, Cash from Operations has averaged 126131294.12 across 5 years, with a median of 116139000.0 in 2024.
- The sharpest annual moves came in 2024 and 2025: Cash from Operations slumped 453.38% in 2024, then surged 226.24% in 2025.
- A 5-year view of Cash from Operations shows it stood at 200195000.0 in 2022, then soared by 116.42% to 32865000.0 in 2023, then plunged by 453.38% to 116139000.0 in 2024, then retreated by 18.57% to 137709000.0 in 2025, then slumped by 475.72% to 792819000.0 in 2026.
- The last three Cash from Operations figures came in at 792819000.0 (Q1 2026), 137709000.0 (Q4 2025), and 131437000.0 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Ops. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -1.67 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -12.20 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.49 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.43 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -792.82 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -792.82 Mn |
| Mar 31, 2026 | -792.82 Mn |
| Dec 31, 2025 | -137.71 Mn |
| Dec 31, 2025 | -137.71 Mn |
| Sep 30, 2025 | -131.44 Mn |
| Sep 30, 2025 | -131.44 Mn |
| Jun 30, 2025 | 151.34 Mn |
| Jun 30, 2025 | 151.34 Mn |
| Mar 31, 2025 | -150.78 Mn |
| Mar 31, 2025 | -150.78 Mn |
| Dec 31, 2024 | -116.14 Mn |
| Dec 31, 2024 | -116.14 Mn |
| Sep 30, 2024 | -114.99 Mn |
| Sep 30, 2024 | -114.99 Mn |
| Jun 30, 2024 | -119.88 Mn |
| Jun 30, 2024 | -119.88 Mn |
| Mar 31, 2024 | -149.94 Mn |
| Mar 31, 2024 | -149.94 Mn |
| Dec 31, 2023 | 32.87 Mn |
| Dec 31, 2023 | 32.87 Mn |