Growth Metrics

Ionis Pharmaceuticals (IONS) Cash from Operations (2016 - 2025)

Historic Cash from Operations for Ionis Pharmaceuticals (IONS) over the last 17 years, with Q3 2025 value amounting to -$131.4 million.

  • Ionis Pharmaceuticals' Cash from Operations fell 1430.3% to -$131.4 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$247.0 million, marking a year-over-year increase of 2981.45%. This contributed to the annual value of -$500.9 million for FY2024, which is 6290.27% down from last year.
  • According to the latest figures from Q3 2025, Ionis Pharmaceuticals' Cash from Operations is -$131.4 million, which was down 1430.3% from $151.3 million recorded in Q2 2025.
  • In the past 5 years, Ionis Pharmaceuticals' Cash from Operations registered a high of $203.7 million during Q4 2021, and its lowest value of -$200.2 million during Q4 2022.
  • Moreover, its 5-year median value for Cash from Operations was -$97.4 million (2023), whereas its average is -$62.3 million.
  • Its Cash from Operations has fluctuated over the past 5 years, first crashed by 61999.47% in 2021, then surged by 22624.12% in 2025.
  • Quarter analysis of 5 years shows Ionis Pharmaceuticals' Cash from Operations stood at $203.7 million in 2021, then plummeted by 198.29% to -$200.2 million in 2022, then surged by 116.42% to $32.9 million in 2023, then crashed by 453.38% to -$116.1 million in 2024, then decreased by 13.17% to -$131.4 million in 2025.
  • Its Cash from Operations stands at -$131.4 million for Q3 2025, versus $151.3 million for Q2 2025 and -$150.8 million for Q1 2025.