Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026)
Ionis Pharmaceuticals' Cash from Operations came in at $565.53 million for Q2 2026, up 273.7% from $151.34 million a year earlier.
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Analysis
Ionis Pharmaceuticals (IONS) Cash from Operations (2009 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Ionis Pharmaceuticals reported Cash from Operations of -$496.43 million; for FY2025, it came in at -$268.58 million.
- Going back by year, Cash from Operations was -$500.95 million in FY2024, -$307.51 million in FY2023, -$274.37 million in FY2022 and $30.8 million in FY2021 (-14.2%).
- The Q2 2026 figure represents the highest quarterly Cash from Operations in data going back to Q3 2009.
- Business Quant data shows IONS's Cash from Operations at -$792.82 million (Q1 2026), -$137.71 million (Q4 2025) and -$131.44 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Ops. (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 8.62 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 3.44 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 5.37 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 5.88 Bn |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 4.58 Bn |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 4.00 Bn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | 3.57 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 835.00 Mn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 1.13 Bn |
| 10 | Ionis Pharmaceuticals | 7.40 Bn | -1.50 Bn | 265.21 Mn | 565.53 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 565.53 Mn |
| Mar 31, 2026 | -792.82 Mn |
| Dec 31, 2025 | -137.71 Mn |
| Sep 30, 2025 | -131.44 Mn |
| Jun 30, 2025 | 151.34 Mn |
| Mar 31, 2025 | -150.78 Mn |
| Dec 31, 2024 | -116.14 Mn |
| Sep 30, 2024 | -114.99 Mn |
| Jun 30, 2024 | -119.88 Mn |
| Mar 31, 2024 | -149.94 Mn |
| Dec 31, 2023 | 32.87 Mn |
| Sep 30, 2023 | -109.02 Mn |
| Jun 30, 2023 | -97.36 Mn |
| Mar 31, 2023 | -133.99 Mn |
| Dec 31, 2022 | -200.20 Mn |
| Sep 30, 2022 | -24.43 Mn |
| Jun 30, 2022 | -18.10 Mn |
| Mar 31, 2022 | -31.65 Mn |
| Dec 31, 2021 | 203.69 Mn |
| Sep 30, 2021 | -55.57 Mn |
API Access
Ionis Pharmaceuticals Cash from Operations API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-from-operations&ticker=IONS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-from-operations", "ticker": "IONS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=cash-from-operations&ticker=IONS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();