Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Cash from Investing Activities of $536.8 million in Q1 2026, up 227.97% quarter-over-quarter from -$419.5 million in Q4 2025, and up 214.93% on a YoY basis from $170.5 million in Q1 2025.

Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Cash from Investing Activities history runs 18 years deep, the most recent figure standing at $536.8 million for Q1 2026.

  • In Q1 2026, Cash from Investing Activities rose 214.93% year-over-year to $536.8 million; the TTM figure through Mar 2026 stood at $88.6 million (up 323.29% YoY), while the FY2025 annual figure was -$277.8 million, down 107.25% from the prior year.
  • Cash from Investing Activities was $536.8 million for Q1 2026 at Ionis Pharmaceuticals, up from -$419.5 million in the prior quarter.
  • In the past five years, Cash from Investing Activities ranged from a high of $536.8 million in Q1 2026 to a low of -$419.5 million in Q4 2025.
  • Historically, Cash from Investing Activities has averaged -$20.7 million across 5 years, with a median of $62.4 million in 2024.
  • The sharpest annual moves came in 2023 and 2025: Cash from Investing Activities soared 2203.96% in 2023, then slumped 714.99% in 2025.
  • A 5-year view of Cash from Investing Activities shows it stood at $212.1 million in 2022, then tumbled by 112.59% to -$26.7 million in 2023, then surged by 355.36% to $68.2 million in 2024, then plunged by 714.99% to -$419.5 million in 2025, then soared by 227.97% to $536.8 million in 2026.
  • The last three Cash from Investing Activities figures came in at $536.8 million (Q1 2026), -$419.5 million (Q4 2025), and $91.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.89 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 638.50 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -431.90 Mn
9 Abivax 91.96 Bn 91.96 Bn - 579,519.10
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn 536.82 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 536.82 Mn
Mar 31, 2026 536.82 Mn
Dec 31, 2025 -419.51 Mn
Dec 31, 2025 -419.51 Mn
Sep 30, 2025 91.34 Mn
Sep 30, 2025 91.34 Mn
Jun 30, 2025 -120.07 Mn
Jun 30, 2025 -120.07 Mn
Mar 31, 2025 170.46 Mn
Mar 31, 2025 170.46 Mn
Dec 31, 2024 68.21 Mn
Dec 31, 2024 68.21 Mn
Sep 30, 2024 -340.80 Mn
Sep 30, 2024 -340.80 Mn
Jun 30, 2024 62.45 Mn
Jun 30, 2024 62.45 Mn
Mar 31, 2024 76.11 Mn
Mar 31, 2024 76.11 Mn
Dec 31, 2023 -26.71 Mn
Dec 31, 2023 -26.71 Mn