Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026)
Ionis Pharmaceuticals' (IONS) quarterly Cash from Investing Activities came in at $536.8 million in Q1 2026, up 214.93% year-on-year from $170.5 million in Q1 2025, and up 227.97% quarter-over-quarter from -$419.5 million in Q4 2025.
Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Cash from Investing Activities history runs 18 years deep, the most recent figure standing at $536.8 million for Q1 2026.
- On a quarterly basis, Cash from Investing Activities rose 214.93% year-over-year to $536.8 million in Q1 2026; TTM through Mar 2026 was $88.6 million, a 323.29% increase from a year earlier, with the FY2025 full-year figure at -$277.8 million, down 107.25% from the prior year.
- Cash from Investing Activities rose to $536.8 million in Q1 2026 per IONS's latest filing, from -$419.5 million in the prior quarter.
- Across five years, Cash from Investing Activities topped out at $536.8 million in Q1 2026 and bottomed at -$419.5 million in Q4 2025.
- The 5-year median for Cash from Investing Activities is $62.4 million (2024), against an average of -$20.7 million.
- Across the five-year window, Cash from Investing Activities surged 2203.96% in 2023 and slumped 714.99% in 2025, its largest moves.
- Year by year, Cash from Investing Activities stood at $212.1 million in 2022, then sank by 112.59% to -$26.7 million in 2023, then surged by 355.36% to $68.2 million in 2024, then slumped by 714.99% to -$419.5 million in 2025, then soared by 227.97% to $536.8 million in 2026.
- Per Business Quant, the three latest IONS Cash from Investing Activities figures stand at $536.8 million (Q1 2026), -$419.5 million (Q4 2025), and $91.3 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing Activities (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | - |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | -45.51 Mn |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | -431.90 Mn |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | -428.90 Mn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | - |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | 172.62 Mn |
| 10 | Ionis Pharmaceuticals | 9.27 Bn | 7.36 Bn | 243.11 Mn | 536.82 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 536.82 Mn |
| Mar 31, 2026 | 536.82 Mn |
| Dec 31, 2025 | -419.51 Mn |
| Dec 31, 2025 | -419.51 Mn |
| Sep 30, 2025 | 91.34 Mn |
| Sep 30, 2025 | 91.34 Mn |
| Jun 30, 2025 | -120.07 Mn |
| Jun 30, 2025 | -120.07 Mn |
| Mar 31, 2025 | 170.46 Mn |
| Mar 31, 2025 | 170.46 Mn |
| Dec 31, 2024 | 68.21 Mn |
| Dec 31, 2024 | 68.21 Mn |
| Sep 30, 2024 | -340.80 Mn |
| Sep 30, 2024 | -340.80 Mn |
| Jun 30, 2024 | 62.45 Mn |
| Jun 30, 2024 | 62.45 Mn |
| Mar 31, 2024 | 76.11 Mn |
| Mar 31, 2024 | 76.11 Mn |
| Dec 31, 2023 | -26.71 Mn |
| Dec 31, 2023 | -26.71 Mn |