Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly Cash from Investing Activities of $536.8 million in Q1 2026, up 227.97% quarter-over-quarter from -$419.5 million in Q4 2025, and up 214.93% on a YoY basis from $170.5 million in Q1 2025.
Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Cash from Investing Activities history runs 18 years deep, the most recent figure standing at $536.8 million for Q1 2026.
- In Q1 2026, Cash from Investing Activities rose 214.93% year-over-year to $536.8 million; the TTM figure through Mar 2026 stood at $88.6 million (up 323.29% YoY), while the FY2025 annual figure was -$277.8 million, down 107.25% from the prior year.
- Cash from Investing Activities was $536.8 million for Q1 2026 at Ionis Pharmaceuticals, up from -$419.5 million in the prior quarter.
- In the past five years, Cash from Investing Activities ranged from a high of $536.8 million in Q1 2026 to a low of -$419.5 million in Q4 2025.
- Historically, Cash from Investing Activities has averaged -$20.7 million across 5 years, with a median of $62.4 million in 2024.
- The sharpest annual moves came in 2023 and 2025: Cash from Investing Activities soared 2203.96% in 2023, then slumped 714.99% in 2025.
- A 5-year view of Cash from Investing Activities shows it stood at $212.1 million in 2022, then tumbled by 112.59% to -$26.7 million in 2023, then surged by 355.36% to $68.2 million in 2024, then plunged by 714.99% to -$419.5 million in 2025, then soared by 227.97% to $536.8 million in 2026.
- The last three Cash from Investing Activities figures came in at $536.8 million (Q1 2026), -$419.5 million (Q4 2025), and $91.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing Activities (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.89 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 638.50 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -431.90 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 579,519.10 |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | 536.82 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 536.82 Mn |
| Mar 31, 2026 | 536.82 Mn |
| Dec 31, 2025 | -419.51 Mn |
| Dec 31, 2025 | -419.51 Mn |
| Sep 30, 2025 | 91.34 Mn |
| Sep 30, 2025 | 91.34 Mn |
| Jun 30, 2025 | -120.07 Mn |
| Jun 30, 2025 | -120.07 Mn |
| Mar 31, 2025 | 170.46 Mn |
| Mar 31, 2025 | 170.46 Mn |
| Dec 31, 2024 | 68.21 Mn |
| Dec 31, 2024 | 68.21 Mn |
| Sep 30, 2024 | -340.80 Mn |
| Sep 30, 2024 | -340.80 Mn |
| Jun 30, 2024 | 62.45 Mn |
| Jun 30, 2024 | 62.45 Mn |
| Mar 31, 2024 | 76.11 Mn |
| Mar 31, 2024 | 76.11 Mn |
| Dec 31, 2023 | -26.71 Mn |
| Dec 31, 2023 | -26.71 Mn |