Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Cash from Investing Activities came in at $536.8 million in Q1 2026, up 214.93% year-on-year from $170.5 million in Q1 2025, and up 227.97% quarter-over-quarter from -$419.5 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Cash from Investing Activities (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Cash from Investing Activities history runs 18 years deep, the most recent figure standing at $536.8 million for Q1 2026.

  • On a quarterly basis, Cash from Investing Activities rose 214.93% year-over-year to $536.8 million in Q1 2026; TTM through Mar 2026 was $88.6 million, a 323.29% increase from a year earlier, with the FY2025 full-year figure at -$277.8 million, down 107.25% from the prior year.
  • Cash from Investing Activities rose to $536.8 million in Q1 2026 per IONS's latest filing, from -$419.5 million in the prior quarter.
  • Across five years, Cash from Investing Activities topped out at $536.8 million in Q1 2026 and bottomed at -$419.5 million in Q4 2025.
  • The 5-year median for Cash from Investing Activities is $62.4 million (2024), against an average of -$20.7 million.
  • Across the five-year window, Cash from Investing Activities surged 2203.96% in 2023 and slumped 714.99% in 2025, its largest moves.
  • Year by year, Cash from Investing Activities stood at $212.1 million in 2022, then sank by 112.59% to -$26.7 million in 2023, then surged by 355.36% to $68.2 million in 2024, then slumped by 714.99% to -$419.5 million in 2025, then soared by 227.97% to $536.8 million in 2026.
  • Per Business Quant, the three latest IONS Cash from Investing Activities figures stand at $536.8 million (Q1 2026), -$419.5 million (Q4 2025), and $91.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn -45.51 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn -431.90 Mn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn -428.90 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -
9 Revolution Medicines 37.35 Bn 37.35 Bn - 172.62 Mn
10 Ionis Pharmaceuticals 9.27 Bn 7.36 Bn 243.11 Mn 536.82 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 536.82 Mn
Mar 31, 2026 536.82 Mn
Dec 31, 2025 -419.51 Mn
Dec 31, 2025 -419.51 Mn
Sep 30, 2025 91.34 Mn
Sep 30, 2025 91.34 Mn
Jun 30, 2025 -120.07 Mn
Jun 30, 2025 -120.07 Mn
Mar 31, 2025 170.46 Mn
Mar 31, 2025 170.46 Mn
Dec 31, 2024 68.21 Mn
Dec 31, 2024 68.21 Mn
Sep 30, 2024 -340.80 Mn
Sep 30, 2024 -340.80 Mn
Jun 30, 2024 62.45 Mn
Jun 30, 2024 62.45 Mn
Mar 31, 2024 76.11 Mn
Mar 31, 2024 76.11 Mn
Dec 31, 2023 -26.71 Mn
Dec 31, 2023 -26.71 Mn