Insmed (INSM) EBITDA Margin (2011 - 2026)
Insmed (INSM) recorded EBITDA Margin of 0.87% in Q2 2026, up 288.66 percentage points from -287.79% a year earlier and up 49.34 percentage points from the prior quarter.
Insmed (INSM) EBITDA Margin (2011 - 2026) Analysis & Trends
On a TTM basis, Insmed's EBITDA Margin came in at -72.15% as of Jun 30, 2026, up 177.15 percentage points year-over-year; for FY2025, it came in at -202.88%, up 35.55 percentage points from FY2024.
- Annual EBITDA Margin has a five-year change of -50.17 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -238.43% in FY2024 (-9.39 pp), -229.04% in FY2023 (-46.87 pp), -182.17% in FY2022 (+9.34 pp) and -191.50% in FY2021 (-38.79 pp).
- The Q2 2026 figure is the highest quarterly EBITDA Margin in data going back to Q1 2011.
- On a year-over-year basis, EBITDA Margin has increased for three consecutive quarters, with an average year-over-year change of +59.72 percentage points over the last eight quarters.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 288.66 percentage points in Q2 2026, against a drop of 169.64 percentage points in Q2 2023 at the low end.
- Per Business Quant, the preceding three quarters came in at -48.47% (Q1 2026), -119.08% (Q4 2025) and -254.32% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Insmed | 25.69 Bn | 20.19 Bn | 358.27 Mn | 0.87% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 0.87% |
| Mar 31, 2026 | -48.47% |
| Dec 31, 2025 | -119.08% |
| Sep 30, 2025 | -254.32% |
| Jun 30, 2025 | -287.79% |
| Mar 31, 2025 | -263.94% |
| Dec 31, 2024 | -217.95% |
| Sep 30, 2024 | -225.54% |
| Jun 30, 2024 | -316.81% |
| Mar 31, 2024 | -188.95% |
| Dec 31, 2023 | -209.74% |
| Sep 30, 2023 | -183.27% |
| Jun 30, 2023 | -301.64% |
| Mar 31, 2023 | -223.34% |
| Dec 31, 2022 | -249.59% |
| Sep 30, 2022 | -185.42% |
| Jun 30, 2022 | -132.01% |
| Mar 31, 2022 | -164.35% |
| Dec 31, 2021 | -170.51% |
| Sep 30, 2021 | -214.12% |
Insmed EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=INSM&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "INSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=INSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();