Immunome (IMNM) Return on Sales (2023 - 2026)

Immunome (IMNM) posted Return on Sales of 1.22% for Q1 2026, down 191.63% on a QoQ basis from 0.42% in Q4 2025, and down 107.0% year-over-year from 17.42% in Q1 2025.

Immunome (IMNM) Return on Sales (2023 - 2026) Analysis & Trends

Immunome's Return on Sales history runs 4 years deep, the most recent figure standing at 1.22% for Q1 2026.

  • Quarterly Return on Sales fell 107.0% year-over-year to 1.22% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 1.22% (down 92.0% YoY) and the FY2025 annual result came in at 0.58%, down 13.0% from the prior year.
  • Return on Sales was 1.22% for Q1 2026 at Immunome, down from 0.42% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.02% in Q1 2023 and bottomed at 1.29% in Q1 2024.
  • A 4-year average of 0.38% and a median of 0.3% in 2024 frame the typical range for Return on Sales.
  • Annual changes were most pronounced in 2024 — Return on Sales tumbled 127 bps — and 2025, when it surged 113 bps.
  • Immunome's Return on Sales stood at 0.25% in 2023, then slipped by 23 bps to 0.3% in 2024, then plunged by 37 bps to 0.42% in 2025, then tumbled by 192 bps to 1.22% in 2026.
  • Business Quant data shows IMNM's Return on Sales at 1.22% in Q1 2026, 0.42% in Q4 2025, and 0.31% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Immunome 2.49 Bn 1.91 Bn - -1.22%

Historic Data

Download Data
DateValue
Mar 31, 2026 -1.22%
Dec 31, 2025 -0.42%
Sep 30, 2025 -0.31%
Jun 30, 2025 -0.18%
Mar 31, 2025 -0.15%
Dec 31, 2024 -0.30%
Sep 30, 2024 -0.40%
Jun 30, 2024 -0.36%
Mar 31, 2024 -1.29%
Dec 31, 2023 -0.25%
Sep 30, 2023 -0.04%
Jun 30, 2023 -0.04%
Mar 31, 2023 -0.02%