Immunome Inc. (IMNM) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

75,506,102Shares Outstanding

5,035,974Shares held by institutions

$114,266,250Value of institutional holdings

135.39%Institutional ownership %

23.53%Shares Changed QoQ

174No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 174 institutions have reported a stake in Immunome Inc. (NASDAQ:IMNM) as of December 2025, according to recent 13F filings with the SEC.

These investors collectively held 135.4% of the company's total shares outstanding in December 2025, up from 122.5% in September 2025.
The company experienced a 23.53% quarterly change in institutional shares held, alongside an increase of 46.22% in total owners annually.
Of these 174 institutional investors, 121 increased their holdings in Immunome, while 34 of them reduced positions, and 19 investors maintained their exposure.
Collectively, institutional investors increased their stake in Immunome to 102.23Mn shares as of December 2025, a change that is up by 19.47Mn shares quarter on quarter and up 49.35Mn shares year over year.
FMR LLC's holding of 16.55Mn shares as of December 31, 2025 makes it the primary institutional investor in Immunome, owning 21.92% of the stock.
Among the most significant buyers of Immunome during December 2025 were FMR LLC (3.49Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (3.01Mn), JPMORGAN CHASE & CO (2.82Mn), Point72 Asset Management, L.P. (2.21Mn), BlackRock, Inc. (1.77Mn).
Leading sellers of Immunome stock in December 2025 included T. Rowe Price Investment Management, Inc. (7.20Mn), Caption Management, LLC (2.06Mn), EcoR1 Capital, LLC (1.22Mn), Candriam S.C.A. (319.64K), UBS Group AG (276.75K).
The top 10 institutional holders of Immunome for the quarter ending December 2025 included FMR LLC (16.55Mn), BlackRock, Inc. (7.59Mn), Point72 Asset Management, L.P. (7.03Mn), VANGUARD GROUP INC (6.04Mn), Redmile Group, LLC (5.72Mn), Enavate Sciences GP, LLC (4.77Mn), PRIMECAP MANAGEMENT CO/CA/ (4.69Mn), STATE STREET CORP (3.87Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (3.71Mn), JPMORGAN CHASE & CO (2.86Mn).

174 Institutional Holders

5,035,974 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	16,549,716	3,493,007	26.75%	$355,487,900.00
BlackRock, Inc.	31 Dec, 2025	7,594,996	1,772,260	30.44%	$163,140,515.00
Point72 Asset Management, L.P.	31 Dec, 2025	7,034,952	2,210,448	45.82%	$151,110,769.00
VANGUARD GROUP INC	31 Dec, 2025	6,038,414	1,144,788	23.39%	$129,705,133.00
Redmile Group, LLC	31 Dec, 2025	5,718,385	695,000	13.84%	$122,830,910.00
Enavate Sciences GP, LLC	31 Dec, 2025	4,768,583	0	0.00%	$102,429,163.00
PRIMECAP MANAGEMENT CO/CA/	31 Dec, 2025	4,685,441	1,667,432	55.25%	$100,643,273.00
STATE STREET CORP	31 Dec, 2025	3,868,000	1,064,027	37.95%	$83,084,640.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	3,705,974	3,009,423	432.05%	$79,604,322.00
JPMORGAN CHASE & CO	31 Dec, 2025	2,855,747	2,823,144	8,659.15%	$61,341,446.00
EcoR1 Capital, LLC	31 Dec, 2025	2,855,590	-1,223,825	-30.00%	$61,338,073.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,361,381	466,806	24.64%	$50,731,482.00
Jefferies Financial Group Inc.	31 Dec, 2025	2,000,000	-100,000	-4.76%	$42,960,000.00
READYSTATE ASSET MANAGEMENT LP	31 Dec, 2025	1,843,210	524,920	39.82%	$39,592,151.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,740,705	899,567	106.95%	$37,390,343.00
MORGAN STANLEY	31 Dec, 2025	1,709,089	-124,729	-6.80%	$36,711,252.00
Sofinnova Investments, Inc.	31 Dec, 2025	1,618,477	1,182,426	271.17%	$34,764,886.00
Woodline Partners LP	31 Dec, 2025	1,575,398	300,669	23.59%	$33,839,549.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	1,429,680	1,429,680	0.00%	$30,709,526.00
PRINCIPAL FINANCIAL GROUP INC	31 Dec, 2025	1,404,450	299,512	27.11%	$30,167,586.00

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