Growth Metrics

Harmony Biosciences Holdings (HRMY) EBITDA Margin (2020 - 2026)

Harmony Biosciences Holdings recorded quarterly EBITDA Margin of 14.73% in Q1 2026, up 59.78% quarter-over-quarter from 9.22% in Q4 2025, and down 1003.0% year-over-year from 1.63% in Q1 2025.

Harmony Biosciences Holdings' EBITDA Margin history runs 7 years deep, the most recent figure standing at 14.73% for Q1 2026.

  • In Q1 2026, EBITDA Margin fell 1003.0% year-over-year to 14.73%; the TTM figure through Mar 2026 stood at 16.12% (down 444.0% YoY), while the FY2025 annual figure was 18.3%, down 206.0% from the prior year.
  • EBITDA Margin came in at 14.73% for Q1 2026 at Harmony Biosciences Holdings, up from 9.22% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 74.91% in Q3 2022 to a low of 6.67% in Q2 2024.
  • A 5-year average of 24.75% and a median of 24.37% in 2024 frame the typical range for EBITDA Margin.
  • Across the five-year window, EBITDA Margin surged 8682 bps in 2022 and tumbled 5090 bps in 2023, its largest moves.
  • Harmony Biosciences Holdings' EBITDA Margin stood at 37.83% in 2022, then plunged by 57 bps to 16.11% in 2023, then surged by 51 bps to 24.37% in 2024, then slumped by 62 bps to 9.22% in 2025, then surged by 60 bps to 14.73% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 14.73%, 9.22%, and 21.29% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 Harmony Biosciences Holdings 1.83 Bn 1.19 Bn 170.88 Mn 14.73%

Historic Data

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DateValue
Mar 31, 2026 14.73%
Dec 31, 2025 9.22%
Sep 30, 2025 21.29%
Jun 30, 2025 19.84%
Mar 31, 2025 24.76%
Dec 31, 2024 24.37%
Sep 30, 2024 25.17%
Jun 30, 2024 6.67%
Mar 31, 2024 24.68%
Dec 31, 2023 16.11%
Sep 30, 2023 24.00%
Jun 30, 2023 25.19%
Mar 31, 2023 24.85%
Dec 31, 2022 37.83%
Sep 30, 2022 74.91%
Jun 30, 2022 21.96%
Mar 31, 2022 25.18%
Dec 31, 2021 24.90%
Sep 30, 2021 -11.92%
Jun 30, 2021 19.12%
Mar 31, 2021 24.35%
Dec 31, 2020 13.78%
Sep 30, 2020 22.76%
Jun 30, 2020 19.23%
Mar 31, 2020 -48.43%