HCW Biologics (HCWB) Return on Sales (2022 - 2025)
HCW Biologics' (HCWB) quarterly Return on Sales came in at 1.73% in Q4 2025, down 165.0% YoY from 2.66% in Q4 2024, and up 21.02% on a QoQ basis from 2.19% in Q3 2025.
HCW Biologics (HCWB) Return on Sales (2022 - 2025) Analysis & Trends
HCW Biologics (HCWB) has 4 years of Return on Sales data on file, last reported at 1.73% in Q4 2025.
- Quarterly Return on Sales fell 165.0% year-over-year to 1.73% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 2.58% (down 247.0% YoY) and the FY2025 annual result came in at 7.48%, down 727.0% from the prior year.
- Return on Sales improved to 1.73% in Q4 2025, from 2.19% in the prior quarter.
- In the past five years, Return on Sales ranged from a high of 0.01% in Q1 2022 to a low of 5.64% in Q2 2025.
- A 4-year average of 1.01% and a median of 0.09% in 2024 frame the typical range for Return on Sales.
- Annual changes were most pronounced in 2024 — Return on Sales soared 124 bps — and 2025, when it plunged 539 bps.
- Tracing HCWB's Return on Sales over 4 years: stood at 0.04% in 2022, then sank by 89 bps to 0.08% in 2023, then retreated by 4 bps to 0.08% in 2024, then tumbled by 1956 bps to 1.73% in 2025.
- The last three Return on Sales figures came in at 1.73% (Q4 2025), 2.19% (Q3 2025), and 5.64% (Q2 2025), per Business Quant data.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 0.00% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 0.00% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 0.00% |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -0.05% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 0.00% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 0.00% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | 0.00% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 0.00% |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | 0.00% |
| 10 | HCW Biologics | 2.93 Mn | 2.19 Mn | -93,887.00 | -0.38% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -1.73% |
| Sep 30, 2025 | -2.19% |
| Jun 30, 2025 | -5.64% |
| Mar 31, 2025 | -4.39% |
| Dec 31, 2024 | -0.08% |
| Sep 30, 2024 | -0.09% |
| Jun 30, 2024 | -0.25% |
| Mar 31, 2024 | -0.07% |
| Dec 31, 2023 | -0.08% |
| Sep 30, 2023 | -0.08% |
| Jun 30, 2023 | -0.10% |
| Mar 31, 2023 | -1.30% |
| Dec 31, 2022 | -0.04% |
| Sep 30, 2022 | -0.02% |
| Jun 30, 2022 | -0.08% |
| Mar 31, 2022 | -0.01% |