HCW Biologics (HCWB) Net Margin (2022 - 2025)
HCW Biologics' (HCWB) quarterly Net Margin came in at 12832.14% in Q4 2025, down 1197773.0% YoY from N/an in Q4 2024, and up 56.03% on a QoQ basis from 29183.24% in Q3 2025.
HCW Biologics (HCWB) Net Margin (2022 - 2025) Analysis & Trends
HCW Biologics (HCWB) has 4 years of Net Margin data on file, last reported at 12832.14% in Q4 2025.
- Quarterly Net Margin fell 1197773.0% year-over-year to 12832.14% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 41163.64% (down 3999294.0% YoY) and the FY2025 annual result came in at 41117.24%, down 3994754.0% from the prior year.
- Net Margin grew to 12832.14% in Q4 2025, from 29183.24% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 65.99% in Q1 2022 to a low of 184450.82% in Q2 2025.
- A 4-year average of 18274.21% and a median of 884.77% in 2024 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2024 — Net Margin surged 1235692 bps — and 2025, when it tumbled 18198171 bps.
- Tracing HCWB's Net Margin over 4 years: stood at 429.49% in 2022, then sank by 89 bps to 813.2% in 2023, then fell by 5 bps to 854.42% in 2024, then sank by 1402 bps to 12832.14% in 2025.
- The last three Net Margin figures came in at 12832.14% (Q4 2025), 29183.24% (Q3 2025), and 184450.82% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.76 Bn | 130.91 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 86.15 Bn | 78.15 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 64.45 Bn | 59.27 Bn | 1.37 Bn | 31.16% |
| 4 | Moderna | 57.08 Bn | 51.94 Bn | 52.00 Mn | -539.31% |
| 5 | BeOne Medicines | 42.08 Bn | 36.99 Bn | 1.53 Bn | 13.90% |
| 6 | Alnylam Pharmaceuticals | 30.90 Bn | 27.59 Bn | 992.69 Mn | 12.74% |
| 7 | BioNTech SE | 27.76 Bn | 9.37 Bn | 668.28 Mn | -16.51% |
| 8 | Insmed | 27.45 Bn | 26.29 Bn | 358.27 Mn | -3.12% |
| 9 | Royalty Pharma | 27.00 Bn | 26.17 Bn | - | 12.09% |
| 10 | HCW Biologics | 2.72 Mn | 1.98 Mn | -93,887.00 | -11,340.34% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -12,832.14% |
| Sep 30, 2025 | -29,183.24% |
| Jun 30, 2025 | -184,450.82% |
| Mar 31, 2025 | -43,862.27% |
| Dec 31, 2024 | -854.42% |
| Sep 30, 2024 | -915.12% |
| Jun 30, 2024 | -2,469.11% |
| Mar 31, 2024 | -665.09% |
| Dec 31, 2023 | -813.20% |
| Sep 30, 2023 | -806.22% |
| Jun 30, 2023 | -1,013.24% |
| Mar 31, 2023 | -13,022.01% |
| Dec 31, 2022 | -429.49% |
| Sep 30, 2022 | -231.67% |
| Jun 30, 2022 | -773.25% |
| Mar 31, 2022 | -65.99% |