HCW Biologics (HCWB) EBT Margin (2022 - 2025)
HCW Biologics' (HCWB) quarterly EBT Margin came in at 17304.52% in Q4 2025, down 1646274.0% YoY from N/an in Q4 2024, and up 21.02% on a QoQ basis from 21909.5% in Q3 2025.
HCW Biologics (HCWB) EBT Margin (2022 - 2025) Analysis & Trends
HCW Biologics (HCWB) has 4 years of EBT Margin data on file, last reported at 17304.52% in Q4 2025.
- Quarterly EBT Margin fell 1646274.0% year-over-year to 17304.52% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 25829.44% (down 2465964.0% YoY) and the FY2025 annual result came in at 74841.77%, down 7267233.0% from the prior year.
- EBT Margin climbed to 17304.52% in Q4 2025, from 21909.5% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 60.78% in Q1 2022 to a low of 56378.49% in Q2 2025.
- A 4-year average of 10096.17% and a median of 879.77% in 2024 frame the typical range for EBT Margin.
- Annual changes were most pronounced in 2024 — EBT Margin surged 1235692 bps — and 2025, when it tumbled 5390688 bps.
- Tracing HCWB's EBT Margin over 4 years: stood at 429.49% in 2022, then sank by 89 bps to 813.2% in 2023, then retreated by 4 bps to 841.77% in 2024, then tumbled by 1956 bps to 17304.52% in 2025.
- The last three EBT Margin figures came in at 17304.52% (Q4 2025), 21909.5% (Q3 2025), and 56378.49% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 41.75% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 35.61% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 35.71% |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -528.97% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 18.33% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 13.77% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -2.67% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 12.09% |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -25.06% |
| 10 | HCW Biologics | 2.93 Mn | 2.19 Mn | -93,887.00 | -3,849.90% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -17,304.52% |
| Sep 30, 2025 | -21,909.50% |
| Jun 30, 2025 | -56,378.49% |
| Mar 31, 2025 | -43,862.27% |
| Dec 31, 2024 | -841.77% |
| Sep 30, 2024 | -917.77% |
| Jun 30, 2024 | -2,471.61% |
| Mar 31, 2024 | -665.09% |
| Dec 31, 2023 | -813.20% |
| Sep 30, 2023 | -806.22% |
| Jun 30, 2023 | -1,013.24% |
| Mar 31, 2023 | -13,022.01% |
| Dec 31, 2022 | -429.49% |
| Sep 30, 2022 | -231.67% |
| Jun 30, 2022 | -811.10% |
| Mar 31, 2022 | -60.78% |