Fractyl Health (GUTS) Return on Capital Employed (2024 - 2026)

Fractyl Health (GUTS) reported Return on Capital Employed of 97.78% for Q1 2026, up 2826.0% year-on-year from 3.34% in Q1 2025, and little changed quarter-over-quarter from 97.29% in Q4 2025.

Fractyl Health (GUTS) has 3 years of Return on Capital Employed data on file, last reported at 97.78% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed rose 2826.0% year-over-year to 97.78%; the trailing twelve-month figure through Mar 2026 stood at 97.78% (up 2826.0% YoY), and the FY2025 full-year result was 100.42%, up 2882.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 97.78%, roughly flat from 97.29% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 50.73% in Q2 2024 and bottomed at 196.96% in Q2 2025.
  • A 3-year average of 103.38% and a median of 97.29% in 2025 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed slumped 14623 bps in 2025 and surged 2826 bps in 2026, its largest moves.
  • Tracing GUTS's Return on Capital Employed over 3 years: stood at 95.71% in 2024, then retreated by 2 bps to 97.29% in 2025, then declined by 0 bps to 97.78% in 2026.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 97.78%, 97.29%, and 142.16% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - 450.31%
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - -107.40%
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 21.10%
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 10.19%
8 Evaxion A 65.44 Bn 65.42 Bn - -
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 20.34%
10 Fractyl Health 19.24 Mn 19.24 Mn - -97.78%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -97.78%
Dec 31, 2025 -97.29%
Sep 30, 2025 -142.16%
Jun 30, 2025 -196.96%
Mar 31, 2025 -126.04%
Dec 31, 2024 -95.71%
Sep 30, 2024 -67.21%
Jun 30, 2024 -50.73%
Mar 31, 2024 -56.54%