Structure Therapeutics (GPCR) Operating Income (2022 - 2026)
Quarterly Operating Income fell 58.72% to -$89.4 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was -$62.6 million through Mar 2026, down 25.32% year-over-year, with the annual reading at -$29.5 million for FY2025, 15.11% down from the prior year.
Structure Therapeutics' Operating Income history spans 5 years, with the latest figure at -$89.4 million for Q1 2026.
- Operating Income came in at -$89.4 million for Q1 2026, down from $171.0 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $171.0 million in Q4 2025 to a low of -$89.4 million in Q1 2026.
- The 5-year median for Operating Income is -$26.1 million (2023), against an average of -$17.6 million.
- Year-over-year, Operating Income crashed 139.23% in 2023 and then soared 375.87% in 2024.
- Structure Therapeutics' Operating Income stood at -$13.0 million in 2022, then plummeted by 139.23% to -$31.0 million in 2023, then soared by 375.87% to $85.5 million in 2024, then skyrocketed by 100.0% to $171.0 million in 2025, then plummeted by 152.27% to -$89.4 million in 2026.
- Per Business Quant, the three most recent readings for GPCR's Operating Income are -$89.4 million (Q1 2026), $171.0 million (Q4 2025), and -$73.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -2.97 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -15.76 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 642.90 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 268.64 Mn |
| 10 | Structure Therapeutics | 8.43 Bn | 8.43 Bn | - | -89.38 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -89.38 Mn |
| Dec 31, 2025 | 171.01 Mn |
| Sep 30, 2025 | -73.79 Mn |
| Jun 30, 2025 | -70.45 Mn |
| Mar 31, 2025 | -56.31 Mn |
| Dec 31, 2024 | 85.50 Mn |
| Sep 30, 2024 | -45.84 Mn |
| Jun 30, 2024 | -33.32 Mn |
| Mar 31, 2024 | -32.02 Mn |
| Dec 31, 2023 | -30.99 Mn |
| Sep 30, 2023 | -26.15 Mn |
| Jun 30, 2023 | -25.99 Mn |
| Mar 31, 2023 | -19.65 Mn |
| Dec 31, 2022 | -12.96 Mn |
| Sep 30, 2022 | -12.69 Mn |
| Jun 30, 2022 | -13.96 Mn |
| Mar 31, 2022 | -12.95 Mn |