Structure Therapeutics (GPCR) EBT (2022 - 2026)
Structure Therapeutics' (GPCR) quarterly EBT came in at -$75.8 million in Q1 2026, down 62.14% year-on-year from -$200.2 million in Q1 2025, and down 142.75% quarter-over-quarter from $177.3 million in Q4 2025.
Structure Therapeutics (GPCR) EBT (2022 - 2026) Analysis & Trends
Structure Therapeutics' EBT history runs 5 years deep, the most recent figure standing at -$75.8 million for Q1 2026.
- On a quarterly basis, EBT fell 62.14% year-over-year to -$75.8 million in Q1 2026; TTM through Mar 2026 was -$25.7 million, a 14.02% increase from a year earlier, with the FY2025 full-year figure at $3.4 million, up 137.22% from the prior year.
- EBT eased to -$75.8 million in Q1 2026 per GPCR's latest filing, from $177.3 million in the prior quarter.
- Across five years, EBT topped out at $177.3 million in Q4 2025 and bottomed at -$75.8 million in Q1 2026.
- The 5-year median for EBT is -$23.2 million (2023), against an average of -$5.8 million.
- Biggest YoY gain for EBT was 130.9% in 2025; the steepest drop was 136.8% in 2025.
- Year by year, EBT stood at $32.2 million in 2022, then surged by 71.04% to $55.1 million in 2023, then surged by 39.37% to $76.8 million in 2024, then soared by 130.9% to $177.3 million in 2025, then tumbled by 142.75% to -$75.8 million in 2026.
- Per Business Quant, the three latest GPCR EBT figures stand at -$75.8 million (Q1 2026), $177.3 million (Q4 2025), and -$65.6 million (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -36.97 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.31 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 259.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.25 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 831.20 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 438.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -453.82 Mn |
| 10 | Structure Therapeutics | 10.71 Bn | 10.71 Bn | - | -75.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -75.78 Mn |
| Dec 31, 2025 | 177.25 Mn |
| Sep 30, 2025 | -65.60 Mn |
| Jun 30, 2025 | -61.52 Mn |
| Mar 31, 2025 | -46.74 Mn |
| Dec 31, 2024 | 76.76 Mn |
| Sep 30, 2024 | -33.89 Mn |
| Jun 30, 2024 | -25.98 Mn |
| Mar 31, 2024 | -26.01 Mn |
| Dec 31, 2023 | 55.08 Mn |
| Sep 30, 2023 | -23.46 Mn |
| Jun 30, 2023 | -23.16 Mn |
| Mar 31, 2023 | -17.95 Mn |
| Dec 31, 2022 | 32.20 Mn |
| Sep 30, 2022 | -12.34 Mn |
| Jun 30, 2022 | -13.88 Mn |
| Mar 31, 2022 | -13.02 Mn |