Structure Therapeutics (GPCR) EBIT (2022 - 2026)

Structure Therapeutics' (GPCR) quarterly EBIT came in at -$89.4 million in Q1 2026, down 58.72% year-on-year from -$216.5 million in Q1 2025, and down 472.58% quarter-over-quarter from $24.0 million in Q4 2025.

Structure Therapeutics (GPCR) EBIT (2022 - 2026) Analysis & Trends

Structure Therapeutics' EBIT history runs 5 years deep, the most recent figure standing at -$89.4 million for Q1 2026.

  • On a quarterly basis, EBIT fell 58.72% year-over-year to -$89.4 million in Q1 2026; TTM through Mar 2026 was -$209.6 million, a 14.85% decrease from a year earlier, with the FY2025 full-year figure at -$176.6 million, down 11.59% from the prior year.
  • EBIT retreated to -$89.4 million in Q1 2026 per GPCR's latest filing, from $24.0 million in the prior quarter.
  • Across five years, EBIT topped out at $24.0 million in Q4 2025 and bottomed at -$89.4 million in Q1 2026.
  • The 5-year median for EBIT is -$31.0 million (2023), against an average of -$34.1 million.
  • Across the five-year window, EBIT tumbled 139.23% in 2023 and soared 150.97% in 2025, its largest moves.
  • Year by year, EBIT stood at -$13.0 million in 2022, then tumbled by 139.23% to -$31.0 million in 2023, then slumped by 51.84% to -$47.1 million in 2024, then surged by 150.97% to $24.0 million in 2025, then sank by 472.58% to -$89.4 million in 2026.
  • Per Business Quant, the three latest GPCR EBIT figures stand at -$89.4 million (Q1 2026), $24.0 million (Q4 2025), and -$73.8 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Structure Therapeutics 10.71 Bn 10.71 Bn - -89.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -89.38 Mn
Dec 31, 2025 23.99 Mn
Sep 30, 2025 -73.79 Mn
Jun 30, 2025 -70.45 Mn
Mar 31, 2025 -56.31 Mn
Dec 31, 2024 -47.06 Mn
Sep 30, 2024 -45.84 Mn
Jun 30, 2024 -33.32 Mn
Mar 31, 2024 -32.02 Mn
Dec 31, 2023 -30.99 Mn
Sep 30, 2023 -26.15 Mn
Jun 30, 2023 -25.99 Mn
Mar 31, 2023 -19.65 Mn
Dec 31, 2022 -12.96 Mn
Sep 30, 2022 -12.69 Mn
Jun 30, 2022 -13.96 Mn
Mar 31, 2022 -12.95 Mn