Structure Therapeutics (GPCR) EBIT (2022 - 2026)
Structure Therapeutics' (GPCR) quarterly EBIT came in at -$89.4 million in Q1 2026, down 58.72% year-on-year from -$216.5 million in Q1 2025, and down 472.58% quarter-over-quarter from $24.0 million in Q4 2025.
Structure Therapeutics (GPCR) EBIT (2022 - 2026) Analysis & Trends
Structure Therapeutics' EBIT history runs 5 years deep, the most recent figure standing at -$89.4 million for Q1 2026.
- On a quarterly basis, EBIT fell 58.72% year-over-year to -$89.4 million in Q1 2026; TTM through Mar 2026 was -$209.6 million, a 14.85% decrease from a year earlier, with the FY2025 full-year figure at -$176.6 million, down 11.59% from the prior year.
- EBIT retreated to -$89.4 million in Q1 2026 per GPCR's latest filing, from $24.0 million in the prior quarter.
- Across five years, EBIT topped out at $24.0 million in Q4 2025 and bottomed at -$89.4 million in Q1 2026.
- The 5-year median for EBIT is -$31.0 million (2023), against an average of -$34.1 million.
- Across the five-year window, EBIT tumbled 139.23% in 2023 and soared 150.97% in 2025, its largest moves.
- Year by year, EBIT stood at -$13.0 million in 2022, then tumbled by 139.23% to -$31.0 million in 2023, then slumped by 51.84% to -$47.1 million in 2024, then surged by 150.97% to $24.0 million in 2025, then sank by 472.58% to -$89.4 million in 2026.
- Per Business Quant, the three latest GPCR EBIT figures stand at -$89.4 million (Q1 2026), $24.0 million (Q4 2025), and -$73.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Structure Therapeutics | 10.71 Bn | 10.71 Bn | - | -89.38 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -89.38 Mn |
| Dec 31, 2025 | 23.99 Mn |
| Sep 30, 2025 | -73.79 Mn |
| Jun 30, 2025 | -70.45 Mn |
| Mar 31, 2025 | -56.31 Mn |
| Dec 31, 2024 | -47.06 Mn |
| Sep 30, 2024 | -45.84 Mn |
| Jun 30, 2024 | -33.32 Mn |
| Mar 31, 2024 | -32.02 Mn |
| Dec 31, 2023 | -30.99 Mn |
| Sep 30, 2023 | -26.15 Mn |
| Jun 30, 2023 | -25.99 Mn |
| Mar 31, 2023 | -19.65 Mn |
| Dec 31, 2022 | -12.96 Mn |
| Sep 30, 2022 | -12.69 Mn |
| Jun 30, 2022 | -13.96 Mn |
| Mar 31, 2022 | -12.95 Mn |