Structure Therapeutics (GPCR) EBIT (2022 - 2026)

Structure Therapeutics (GPCR) recorded quarterly EBIT of -$89.4 million in Q1 2026, down 152.27% quarter-over-quarter from $171.0 million in Q4 2025, and down 58.72% on a YoY basis from -$216.5 million in Q1 2025.

Structure Therapeutics (GPCR) EBIT (2022 - 2026) Analysis & Trends

Structure Therapeutics' EBIT history runs 5 years deep, the most recent figure standing at -$89.4 million for Q1 2026.

  • In Q1 2026, EBIT fell 58.72% year-over-year to -$89.4 million; the TTM figure through Mar 2026 stood at -$62.6 million (down 25.32% YoY), while the FY2025 annual figure was -$29.5 million, down 15.11% from the prior year.
  • EBIT was -$89.4 million for Q1 2026 at Structure Therapeutics, down from $171.0 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of $171.0 million in Q4 2025 to a low of -$89.4 million in Q1 2026.
  • Historically, EBIT has averaged -$17.6 million across 5 years, with a median of -$26.1 million in 2023.
  • The sharpest annual moves came in 2023 and 2024: EBIT tumbled 139.23% in 2023, then jumped 375.87% in 2024.
  • A 5-year view of EBIT shows it stood at -$13.0 million in 2022, then sank by 139.23% to -$31.0 million in 2023, then jumped by 375.87% to $85.5 million in 2024, then surged by 100.0% to $171.0 million in 2025, then plunged by 152.27% to -$89.4 million in 2026.
  • The last three EBIT figures came in at -$89.4 million (Q1 2026), $171.0 million (Q4 2025), and -$73.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -15.76 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -1.51 Mn
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Structure Therapeutics 9.35 Bn 9.35 Bn - -89.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -89.38 Mn
Dec 31, 2025 171.01 Mn
Sep 30, 2025 -73.79 Mn
Jun 30, 2025 -70.45 Mn
Mar 31, 2025 -56.31 Mn
Dec 31, 2024 85.50 Mn
Sep 30, 2024 -45.84 Mn
Jun 30, 2024 -33.32 Mn
Mar 31, 2024 -32.02 Mn
Dec 31, 2023 -30.99 Mn
Sep 30, 2023 -26.15 Mn
Jun 30, 2023 -25.99 Mn
Mar 31, 2023 -19.65 Mn
Dec 31, 2022 -12.96 Mn
Sep 30, 2022 -12.69 Mn
Jun 30, 2022 -13.96 Mn
Mar 31, 2022 -12.95 Mn