Greenwich LifeSciences (GLSI) Operating Income (2019 - 2026)

Greenwich LifeSciences' (GLSI) quarterly Operating Income came in at -$7.9 million in Q4 2025, up 18.17% YoY from -$6.7 million in Q4 2024, and down 90.32% on a QoQ basis from -$4.2 million in Q3 2025.

Greenwich LifeSciences (GLSI) Operating Income (2019 - 2026) Analysis & Trends

Greenwich LifeSciences (GLSI) has 7 years of Operating Income data on file, last reported at -$7.9 million in Q4 2025.

  • Quarterly Operating Income rose 18.17% year-over-year to -$7.9 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$19.4 million (down 10.27% YoY) and the FY2025 annual result came in at -$19.4 million, down 10.27% from the prior year.
  • Operating Income slipped to -$7.9 million in Q4 2025, from -$4.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$600606.0 in Q1 2021 to a low of -$9.7 million in Q4 2024.
  • A 5-year average of -$3.0 million and a median of -$2.5 million in 2023 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2021 — Operating Income plunged 258.05% — and 2025, when it advanced 18.17%.
  • Tracing GLSI's Operating Income over 5 years: stood at -$2.4 million in 2021, then decreased by 21.77% to -$2.9 million in 2022, then increased by 2.03% to -$2.8 million in 2023, then slumped by 242.36% to -$9.7 million in 2024, then increased by 18.17% to -$7.9 million in 2025.
  • The last three Operating Income figures came in at -$7.9 million (Q4 2025), -$4.2 million (Q3 2025), and -$4.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Greenwich LifeSciences 246.39 Mn 246.39 Mn - -5.73 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -5.73 Mn
Dec 31, 2025 -7.94 Mn
Sep 30, 2025 -4.17 Mn
Jun 30, 2025 -4.05 Mn
Mar 31, 2025 -3.28 Mn
Dec 31, 2024 -9.71 Mn
Sep 30, 2024 -2.73 Mn
Jun 30, 2024 -2.66 Mn
Mar 31, 2024 -2.54 Mn
Dec 31, 2023 -2.84 Mn
Sep 30, 2023 -2.50 Mn
Jun 30, 2023 -1.75 Mn
Mar 31, 2023 -2.24 Mn
Dec 31, 2022 -2.89 Mn
Sep 30, 2022 -2.38 Mn
Jun 30, 2022 -773,307.00
Mar 31, 2022 -1.99 Mn
Dec 31, 2021 -2.38 Mn
Sep 30, 2021 -866,686.00
Jun 30, 2021 -753,445.00