GH Research (GHRS) Operating Income (2020 - 2025)

GH Research's (GHRS) quarterly Operating Income came in at -$16.7 million in Q4 2025, down 29.15% year-on-year from -$23.6 million in Q4 2024, and down 0.92% quarter-over-quarter from -$16.6 million in Q3 2025.

GH Research (GHRS) Operating Income (2020 - 2025) Analysis & Trends

GH Research's Operating Income history runs 6 years deep, the most recent figure standing at -$16.7 million for Q4 2025.

  • On a quarterly basis, Operating Income fell 29.15% year-over-year to -$16.7 million in Q4 2025; TTM through Dec 2025 was -$60.7 million, a 20.68% decrease from a year earlier, with the FY2025 full-year figure at -$60.7 million, down 20.68% from the prior year.
  • Operating Income slipped to -$16.7 million in Q4 2025 per GHRS's latest filing, from -$16.6 million in the prior quarter.
  • Across five years, Operating Income topped out at -$1.1 million in Q1 2021 and bottomed at -$16.7 million in Q4 2025.
  • The 5-year median for Operating Income is -$10.2 million (2023), against an average of -$9.9 million.
  • Across the five-year window, Operating Income slumped 7676.67% in 2021 and decreased 10.44% in 2025, its largest moves.
  • Year by year, Operating Income stood at -$6.6 million in 2021, then sank by 38.53% to -$9.2 million in 2022, then slipped by 21.66% to -$11.2 million in 2023, then declined by 16.0% to -$12.9 million in 2024, then dropped by 29.15% to -$16.7 million in 2025.
  • Per Business Quant, the three latest GHRS Operating Income figures stand at -$16.7 million (Q4 2025), -$16.6 million (Q3 2025), and -$14.7 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 GH Research 1.69 Bn 1.69 Bn - -16.72 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -16.72 Mn
Sep 30, 2025 -16.57 Mn
Jun 30, 2025 -14.70 Mn
Mar 31, 2025 -12.73 Mn
Dec 31, 2024 -12.94 Mn
Sep 30, 2024 -12.62 Mn
Jun 30, 2024 -13.22 Mn
Mar 31, 2024 -11.53 Mn
Dec 31, 2023 -11.16 Mn
Sep 30, 2023 -9.72 Mn
Jun 30, 2023 -9.93 Mn
Mar 31, 2023 -10.42 Mn
Dec 31, 2022 -9.17 Mn
Sep 30, 2022 -6.63 Mn
Jun 30, 2022 -6.75 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 -6.62 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn
Mar 31, 2021 -1.14 Mn