GH Research (GHRS) Operating Income (2020 - 2025)

GH Research (GHRS) recorded quarterly Operating Income of -$16.7 million in Q4 2025, down 0.92% quarter-over-quarter from -$16.6 million in Q3 2025, and down 29.15% on a YoY basis from -$23.6 million in Q4 2024.

GH Research (GHRS) Operating Income (2020 - 2025) Analysis & Trends

GH Research's Operating Income history runs 6 years deep, the most recent figure standing at -$16.7 million for Q4 2025.

  • In Q4 2025, Operating Income fell 29.15% year-over-year to -$16.7 million; the TTM figure through Dec 2025 stood at -$60.7 million (down 20.68% YoY), while the FY2025 annual figure was -$60.7 million, down 20.68% from the prior year.
  • Operating Income was -$16.7 million for Q4 2025 at GH Research, down from -$16.6 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$1.1 million in Q1 2021 to a low of -$16.7 million in Q4 2025.
  • Historically, Operating Income has averaged -$9.9 million across 5 years, with a median of -$10.2 million in 2023.
  • The sharpest annual moves came in 2021 and 2025: Operating Income slumped 7676.67% in 2021, then fell 10.44% in 2025.
  • A 5-year view of Operating Income shows it stood at -$6.6 million in 2021, then tumbled by 38.53% to -$9.2 million in 2022, then slipped by 21.66% to -$11.2 million in 2023, then declined by 16.0% to -$12.9 million in 2024, then dropped by 29.15% to -$16.7 million in 2025.
  • The last three Operating Income figures came in at -$16.7 million (Q4 2025), -$16.6 million (Q3 2025), and -$14.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -32.68 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - -2.97 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -15.76 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -3.82 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 1.14 Bn
9 Abivax 94.26 Bn 94.26 Bn - -65.83 Mn
10 GH Research 9.73 Bn 9.63 Bn - -16.72 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -16.72 Mn
Sep 30, 2025 -16.57 Mn
Jun 30, 2025 -14.70 Mn
Mar 31, 2025 -12.73 Mn
Dec 31, 2024 -12.94 Mn
Sep 30, 2024 -12.62 Mn
Jun 30, 2024 -13.22 Mn
Mar 31, 2024 -11.53 Mn
Dec 31, 2023 -11.16 Mn
Sep 30, 2023 -9.72 Mn
Jun 30, 2023 -9.93 Mn
Mar 31, 2023 -10.42 Mn
Dec 31, 2022 -9.17 Mn
Sep 30, 2022 -6.63 Mn
Jun 30, 2022 -6.75 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 -6.62 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn
Mar 31, 2021 -1.14 Mn