GH Research (GHRS) EBITDA (2020 - 2026)

GH Research (GHRS) posted quarterly EBITDA of -$16.7 million for Q4 2025, down 29.15% year-over-year from -$23.6 million in Q4 2024, and down 0.92% quarter-over-quarter from -$16.6 million in Q3 2025.

GH Research (GHRS) EBITDA (2020 - 2026) Analysis & Trends

GH Research's EBITDA history runs 6 years deep, the most recent figure standing at -$16.7 million for Q4 2025.

  • In Q4 2025, EBITDA fell 29.15% year-over-year to -$16.7 million; the TTM figure through Dec 2025 stood at -$60.7 million (down 20.68% YoY), while the FY2025 annual figure was -$60.4 million, down 20.79% from the prior year.
  • EBITDA for Q4 2025 stood at -$16.7 million, down from -$16.6 million in the prior quarter.
  • The five-year high for EBITDA was -$1.1 million in Q1 2021, with the low at -$16.7 million in Q4 2025.
  • The 5-year median for EBITDA is -$10.2 million (2023), against an average of -$9.9 million.
  • The sharpest annual moves came in 2021 and 2025: EBITDA sank 7676.67% in 2021, then declined 10.44% in 2025.
  • GH Research's EBITDA stood at -$6.6 million in 2021, then slumped by 38.53% to -$9.2 million in 2022, then decreased by 21.66% to -$11.2 million in 2023, then dropped by 16.0% to -$12.9 million in 2024, then slipped by 29.15% to -$16.7 million in 2025.
  • Business Quant data shows GHRS's EBITDA at -$16.7 million in Q4 2025, -$16.6 million in Q3 2025, and -$14.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 GH Research 2.02 Bn 1.68 Bn - -19.46 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -19.46 Mn
Dec 31, 2025 -16.72 Mn
Sep 30, 2025 -16.57 Mn
Jun 30, 2025 -14.70 Mn
Mar 31, 2025 -12.73 Mn
Dec 31, 2024 -12.94 Mn
Sep 30, 2024 -12.62 Mn
Jun 30, 2024 -13.22 Mn
Mar 31, 2024 -11.53 Mn
Dec 31, 2023 -11.16 Mn
Sep 30, 2023 -9.72 Mn
Jun 30, 2023 -9.93 Mn
Mar 31, 2023 -10.42 Mn
Dec 31, 2022 -9.17 Mn
Sep 30, 2022 -6.63 Mn
Jun 30, 2022 -6.75 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 -6.62 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn