GH Research (GHRS) EBITDA (2020 - 2025)

GH Research (GHRS) recorded quarterly EBITDA of -$80.8 million in Q4 2025, down 672.75% quarter-over-quarter from $14.1 million in Q3 2025, and down 623.55% on a YoY basis from $15.4 million in Q4 2024.

GH Research (GHRS) EBITDA (2020 - 2025) Analysis & Trends

GH Research's EBITDA history runs 6 years deep, the most recent figure standing at -$80.8 million for Q4 2025.

  • In Q4 2025, EBITDA fell 623.55% year-over-year to -$80.8 million; the TTM figure through Dec 2025 stood at -$68.0 million (down 65.19% YoY), while the FY2025 annual figure was -$47.6 million, down 15.57% from the prior year.
  • EBITDA was -$80.8 million for Q4 2025 at GH Research, down from $14.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $14.1 million in Q3 2025 to a low of -$80.8 million in Q4 2025.
  • Historically, EBITDA has averaged -$5.4 million across 5 years, with a median of -$5.1 million in 2021.
  • The sharpest annual moves came in 2021 and 2022: EBITDA plunged 19066.67% in 2021, then jumped 1482.72% in 2022.
  • A 5-year view of EBITDA shows it stood at -$11.8 million in 2021, then surged by 37.3% to -$7.4 million in 2022, then decreased by 1.1% to -$7.5 million in 2023, then sank by 49.75% to -$11.2 million in 2024, then sank by 623.55% to -$80.8 million in 2025.
  • The last three EBITDA figures came in at -$80.8 million (Q4 2025), $14.1 million (Q3 2025), and $8.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -26.92 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - -13.63 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -14.44 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -3.82 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 1.14 Bn
9 Abivax 94.26 Bn 94.26 Bn - -65.83 Mn
10 GH Research 9.73 Bn 9.63 Bn - -80.85 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -80.85 Mn
Sep 30, 2025 14.12 Mn
Jun 30, 2025 8.91 Mn
Mar 31, 2025 -10.22 Mn
Dec 31, 2024 -11.17 Mn
Sep 30, 2024 -9.58 Mn
Jun 30, 2024 -10.93 Mn
Mar 31, 2024 -9.50 Mn
Dec 31, 2023 -7.46 Mn
Sep 30, 2023 7.86 Mn
Jun 30, 2023 9.30 Mn
Mar 31, 2023 8.54 Mn
Dec 31, 2022 -7.38 Mn
Sep 30, 2022 6.91 Mn
Jun 30, 2022 6.72 Mn
Mar 31, 2022 -8.02 Mn
Dec 31, 2021 -11.77 Mn
Sep 30, 2021 -2.85 Mn
Jun 30, 2021 -486,000.00
Mar 31, 2021 -202,000.00