GH Research (GHRS) EBITDA (2020 - 2025)
GH Research (GHRS) recorded quarterly EBITDA of -$80.8 million in Q4 2025, down 672.75% quarter-over-quarter from $14.1 million in Q3 2025, and down 623.55% on a YoY basis from $15.4 million in Q4 2024.
GH Research (GHRS) EBITDA (2020 - 2025) Analysis & Trends
GH Research's EBITDA history runs 6 years deep, the most recent figure standing at -$80.8 million for Q4 2025.
- In Q4 2025, EBITDA fell 623.55% year-over-year to -$80.8 million; the TTM figure through Dec 2025 stood at -$68.0 million (down 65.19% YoY), while the FY2025 annual figure was -$47.6 million, down 15.57% from the prior year.
- EBITDA was -$80.8 million for Q4 2025 at GH Research, down from $14.1 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of $14.1 million in Q3 2025 to a low of -$80.8 million in Q4 2025.
- Historically, EBITDA has averaged -$5.4 million across 5 years, with a median of -$5.1 million in 2021.
- The sharpest annual moves came in 2021 and 2022: EBITDA plunged 19066.67% in 2021, then jumped 1482.72% in 2022.
- A 5-year view of EBITDA shows it stood at -$11.8 million in 2021, then surged by 37.3% to -$7.4 million in 2022, then decreased by 1.1% to -$7.5 million in 2023, then sank by 49.75% to -$11.2 million in 2024, then sank by 623.55% to -$80.8 million in 2025.
- The last three EBITDA figures came in at -$80.8 million (Q4 2025), $14.1 million (Q3 2025), and $8.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | - |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -65.83 Mn |
| 10 | GH Research | 9.73 Bn | 9.63 Bn | - | -80.85 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -80.85 Mn |
| Sep 30, 2025 | 14.12 Mn |
| Jun 30, 2025 | 8.91 Mn |
| Mar 31, 2025 | -10.22 Mn |
| Dec 31, 2024 | -11.17 Mn |
| Sep 30, 2024 | -9.58 Mn |
| Jun 30, 2024 | -10.93 Mn |
| Mar 31, 2024 | -9.50 Mn |
| Dec 31, 2023 | -7.46 Mn |
| Sep 30, 2023 | 7.86 Mn |
| Jun 30, 2023 | 9.30 Mn |
| Mar 31, 2023 | 8.54 Mn |
| Dec 31, 2022 | -7.38 Mn |
| Sep 30, 2022 | 6.91 Mn |
| Jun 30, 2022 | 6.72 Mn |
| Mar 31, 2022 | -8.02 Mn |
| Dec 31, 2021 | -11.77 Mn |
| Sep 30, 2021 | -2.85 Mn |
| Jun 30, 2021 | -486,000.00 |
| Mar 31, 2021 | -202,000.00 |