Fulcrum Therapeutics (FULC) Enterprise Value (2018 - 2026)

Fulcrum Therapeutics (FULC) posted quarterly Enterprise Value of -$318.8 million for Q2 2026, down 648.66% year-over-year from $58.1 million in Q2 2025, and up 4.34% quarter-over-quarter from -$333.3 million in Q1 2026.

Fulcrum Therapeutics (FULC) Enterprise Value (2018 - 2026) Analysis & Trends

Fulcrum Therapeutics (FULC) has reported Enterprise Value for 9 consecutive years, with -$318.8 million the latest figure, recorded in Q2 2026.

  • In Q2 2026, Enterprise Value fell 648.66% year-over-year to -$318.8 million; the TTM figure through Jun 2026 stood at -$318.8 million (down 648.66% YoY), while the FY2025 annual figure was -$352.3 million, down 46.17% from the prior year.
  • Enterprise Value rose to -$318.8 million in Q2 2026 per FULC's latest filing, from -$333.3 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$30.1 million in Q3 2023 and bottomed at -$352.3 million in Q4 2025.
  • Historically, Enterprise Value has averaged -$125.8 million across 5 years, with a median of -$57.6 million in 2024.
  • Annual changes were most pronounced in 2022 — Enterprise Value surged 66.93% — and 2026, when it tumbled 690.26%.
  • Fulcrum Therapeutics' Enterprise Value stood at -$35.1 million in 2022, then sank by 573.03% to -$236.2 million in 2023, then slipped by 2.03% to -$241.0 million in 2024, then plunged by 46.17% to -$352.3 million in 2025, then climbed by 9.5% to -$318.8 million in 2026.
  • Business Quant data shows FULC's Enterprise Value at -$318.8 million in Q2 2026, -$333.3 million in Q1 2026, and -$352.3 million in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Fulcrum Therapeutics 285.31 Mn 285.31 Mn - -318.84 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -318.84 Mn
Mar 31, 2026 -50.26 Mn
Dec 31, 2025 -197.53 Mn
Sep 30, 2025 -47.08 Mn
Jun 30, 2025 -214.11 Mn
Mar 31, 2025 -42.18 Mn
Dec 31, 2024 -241.02 Mn
Sep 30, 2024 -72.63 Mn
Jun 30, 2024 -86.70 Mn
Mar 31, 2024 -39.95 Mn
Dec 31, 2023 -236.22 Mn
Sep 30, 2023 -30.08 Mn
Jun 30, 2023 -33.97 Mn
Mar 31, 2023 -34.73 Mn
Dec 31, 2022 -35.10 Mn
Sep 30, 2022 -90.94 Mn
Jun 30, 2022 -40.15 Mn
Mar 31, 2022 -33.31 Mn
Dec 31, 2021 -35.41 Mn
Sep 30, 2021 -65.47 Mn