Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026)
Fulcrum Therapeutics' (FULC) quarterly EBITDA came in at -$22.2 million in Q1 2026, down 8.74% year-on-year from -$24.3 million in Q1 2025, and up 2.23% on a QoQ basis from -$22.7 million in Q4 2025.
Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026) Analysis & Trends
Fulcrum Therapeutics (FULC) has 9 years of EBITDA data on file, last reported at -$22.2 million in Q1 2026.
- On a quarterly basis, EBITDA fell 8.74% year-over-year to -$22.2 million in Q1 2026; TTM through Mar 2026 was -$86.6 million, a 594.3% decrease from a year earlier, with the FY2025 full-year figure at -$84.8 million, down 287.13% from the prior year.
- EBITDA for Q1 2026 stood at -$22.2 million, up from -$22.7 million in the prior quarter.
- Over the last five years, EBITDA for FULC reached as high as $52.5 million in Q2 2024 and fell as low as -$34.2 million in Q2 2022.
- Historically, EBITDA has averaged -$20.7 million across 5 years, with a median of -$25.1 million in 2024.
- Across the five-year window, EBITDA surged 292.33% in 2024 and sank 137.75% in 2025, its largest moves.
- Year by year, EBITDA stood at -$28.0 million in 2022, then declined by 0.07% to -$28.0 million in 2023, then soared by 30.59% to -$19.4 million in 2024, then slipped by 16.8% to -$22.7 million in 2025, then climbed by 2.23% to -$22.2 million in 2026.
- Per Business Quant data, the three most recent EBITDA figures were -$22.2 million in Q1 2026, -$22.7 million in Q4 2025, and -$21.9 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Fulcrum Therapeutics | 285.43 Mn | 285.43 Mn | - | -22.19 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -22.19 Mn |
| Dec 31, 2025 | -22.69 Mn |
| Sep 30, 2025 | -21.86 Mn |
| Jun 30, 2025 | -19.82 Mn |
| Mar 31, 2025 | -20.40 Mn |
| Dec 31, 2024 | -19.43 Mn |
| Sep 30, 2024 | -25.13 Mn |
| Jun 30, 2024 | 52.49 Mn |
| Mar 31, 2024 | -29.83 Mn |
| Dec 31, 2023 | -27.99 Mn |
| Sep 30, 2023 | -27.44 Mn |
| Jun 30, 2023 | -27.29 Mn |
| Mar 31, 2023 | -27.94 Mn |
| Dec 31, 2022 | -27.97 Mn |
| Sep 30, 2022 | -24.36 Mn |
| Jun 30, 2022 | -34.24 Mn |
| Mar 31, 2022 | -26.00 Mn |
| Dec 31, 2021 | -23.56 Mn |
| Sep 30, 2021 | -20.77 Mn |
| Jun 30, 2021 | -19.68 Mn |