Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026)

Fulcrum Therapeutics' (FULC) quarterly EBITDA came in at -$22.2 million in Q1 2026, down 8.74% year-on-year from -$24.3 million in Q1 2025, and up 2.23% on a QoQ basis from -$22.7 million in Q4 2025.

Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026) Analysis & Trends

Fulcrum Therapeutics (FULC) has 9 years of EBITDA data on file, last reported at -$22.2 million in Q1 2026.

  • On a quarterly basis, EBITDA fell 8.74% year-over-year to -$22.2 million in Q1 2026; TTM through Mar 2026 was -$86.6 million, a 594.3% decrease from a year earlier, with the FY2025 full-year figure at -$84.8 million, down 287.13% from the prior year.
  • EBITDA for Q1 2026 stood at -$22.2 million, up from -$22.7 million in the prior quarter.
  • Over the last five years, EBITDA for FULC reached as high as $52.5 million in Q2 2024 and fell as low as -$34.2 million in Q2 2022.
  • Historically, EBITDA has averaged -$20.7 million across 5 years, with a median of -$25.1 million in 2024.
  • Across the five-year window, EBITDA surged 292.33% in 2024 and sank 137.75% in 2025, its largest moves.
  • Year by year, EBITDA stood at -$28.0 million in 2022, then declined by 0.07% to -$28.0 million in 2023, then soared by 30.59% to -$19.4 million in 2024, then slipped by 16.8% to -$22.7 million in 2025, then climbed by 2.23% to -$22.2 million in 2026.
  • Per Business Quant data, the three most recent EBITDA figures were -$22.2 million in Q1 2026, -$22.7 million in Q4 2025, and -$21.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Fulcrum Therapeutics 285.43 Mn 285.43 Mn - -22.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -22.19 Mn
Dec 31, 2025 -22.69 Mn
Sep 30, 2025 -21.86 Mn
Jun 30, 2025 -19.82 Mn
Mar 31, 2025 -20.40 Mn
Dec 31, 2024 -19.43 Mn
Sep 30, 2024 -25.13 Mn
Jun 30, 2024 52.49 Mn
Mar 31, 2024 -29.83 Mn
Dec 31, 2023 -27.99 Mn
Sep 30, 2023 -27.44 Mn
Jun 30, 2023 -27.29 Mn
Mar 31, 2023 -27.94 Mn
Dec 31, 2022 -27.97 Mn
Sep 30, 2022 -24.36 Mn
Jun 30, 2022 -34.24 Mn
Mar 31, 2022 -26.00 Mn
Dec 31, 2021 -23.56 Mn
Sep 30, 2021 -20.77 Mn
Jun 30, 2021 -19.68 Mn