Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026)

Fulcrum Therapeutics (FULC) reported EBITDA of -$19.6 million for Q1 2026, down 10.52% year-over-year from -$21.9 million in Q1 2025, and up 4.03% quarter-over-quarter from -$20.4 million in Q4 2025.

Fulcrum Therapeutics (FULC) EBITDA (2018 - 2026) Analysis & Trends

Fulcrum Therapeutics (FULC) has 9 years of EBITDA data on file, last reported at -$19.6 million in Q1 2026.

  • EBITDA for Q1 2026 came in at -$19.6 million, down 10.52% year-over-year; the trailing twelve-month figure through Mar 2026 was -$79.2 million (down 2548.95% YoY), and the FY2025 annual result was -$74.8 million, down 691.16% from the prior year.
  • EBITDA climbed to -$19.6 million in Q1 2026 per FULC's latest filing, from -$20.4 million in the prior quarter.
  • Over five years, EBITDA peaked at $52.5 million in Q2 2024 and troughed at -$34.0 million in Q2 2022.
  • A 5-year average of -$19.6 million and a median of -$24.4 million in 2022 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2024 and 2025: EBITDA jumped 292.33% in 2024, then tumbled 137.75% in 2025.
  • A 5-year view of EBITDA shows it stood at -$28.0 million in 2022, then decreased by 0.07% to -$28.0 million in 2023, then jumped by 39.92% to -$16.8 million in 2024, then fell by 21.31% to -$20.4 million in 2025, then increased by 4.03% to -$19.6 million in 2026.
  • Business Quant data shows FULC's EBITDA at -$19.6 million in Q1 2026, -$20.4 million in Q4 2025, and -$19.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -13.63 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -14.44 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -752,618.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.71 Bn 91.71 Bn - -65.83 Mn
10 Fulcrum Therapeutics 267.90 Mn 267.90 Mn - -19.58 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -19.58 Mn
Dec 31, 2025 -20.40 Mn
Sep 30, 2025 -19.44 Mn
Jun 30, 2025 -19.82 Mn
Mar 31, 2025 -17.72 Mn
Dec 31, 2024 -16.82 Mn
Sep 30, 2024 -20.95 Mn
Jun 30, 2024 52.49 Mn
Mar 31, 2024 -27.17 Mn
Dec 31, 2023 -27.99 Mn
Sep 30, 2023 -27.44 Mn
Jun 30, 2023 -27.29 Mn
Mar 31, 2023 -27.94 Mn
Dec 31, 2022 -27.97 Mn
Sep 30, 2022 -24.36 Mn
Jun 30, 2022 -34.05 Mn
Mar 31, 2022 -26.62 Mn
Dec 31, 2021 -23.79 Mn
Sep 30, 2021 -20.79 Mn
Jun 30, 2021 -19.65 Mn