Growth Metrics

Amicus Therapeutics (FOLD) Operating Margin: 2009-2025

Historic Operating Margin for Amicus Therapeutics (FOLD) over the last 15 years, with Sep 2025 value amounting to 20.27%.

  • Amicus Therapeutics' Operating Margin rose 497.00% to 20.27% in Q3 2025 from the same period last year, while for Sep 2025 it was 5.48%, marking a year-over-year increase of 442.00%. This contributed to the annual value of 4.71% for FY2024, which is 2404.00% up from last year.
  • As of Q3 2025, Amicus Therapeutics' Operating Margin stood at 20.27%, which was up 430.96% from -6.12% recorded in Q2 2025.
  • Over the past 5 years, Amicus Therapeutics' Operating Margin peaked at 20.27% during Q3 2025, and registered a low of -95.71% during Q1 2022.
  • For the 3-year period, Amicus Therapeutics' Operating Margin averaged around -5.71%, with its median value being -6.12% (2025).
  • In the last 5 years, Amicus Therapeutics' Operating Margin plummeted by 2,492bps in 2022 and then skyrocketed by 5,512bps in 2023.
  • Amicus Therapeutics' Operating Margin (Quarterly) stood at -87.82% in 2021, then spiked by 3,977bps to -48.05% in 2022, then surged by 4,484bps to -3.21% in 2023, then surged by 1,388bps to 10.67% in 2024, then skyrocketed by 497bps to 20.27% in 2025.
  • Its Operating Margin was 20.27% in Q3 2025, compared to -6.12% in Q2 2025 and -6.35% in Q1 2025.