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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Amicus Therapeutics (FOLD) Operating Margin (2016 - 2025)

Amicus Therapeutics filings provide 14 years of Operating Margin readings, the most recent being 8.61% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 206.0% to 8.61% in Q4 2025 year-over-year; TTM through Dec 2025 was 5.17%, a 46.0% increase, with the full-year FY2025 number at 5.17%, up 46.0% from a year prior.
  • Operating Margin hit 8.61% in Q4 2025 for Amicus Therapeutics, down from 20.27% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 20.27% in Q3 2025 to a low of 95.71% in Q1 2022.
  • Median Operating Margin over the past 5 years was 22.53% (2023), compared with a mean of 29.28%.
  • Biggest five-year swings in Operating Margin: crashed -2492bps in 2022 and later soared 5512bps in 2023.
  • Amicus Therapeutics' Operating Margin stood at 87.82% in 2021, then skyrocketed by 45bps to 48.05% in 2022, then surged by 93bps to 3.21% in 2023, then surged by 433bps to 10.67% in 2024, then dropped by -19bps to 8.61% in 2025.
  • The last three reported values for Operating Margin were 8.61% (Q4 2025), 20.27% (Q3 2025), and 6.12% (Q2 2025) per Business Quant data.